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Sassuolo vs Lazio Prediction & Betting Tips - Serie A

Italy - Serie A

Sassuolo
14/09/2025 11:00
Lazio

Prediction :

 

Lazio wins the match

 
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 by Kennedy Kechula | in Serie A Predictions

Going the opening two rounds of Serie A without registering a point has left Sassuolo at the bottom of the standings. They will look to address that when they host Lazio for a Sunday league match. Read on to find our prediction.

Sassuolo have found it tough upon their return to the league. They opened their campaign with a 2-0 loss at home against the champions, Napoli.

I Neroverdi should have done better against Cremonese on matchday two but conceded a late penalty after battling from 2-0 down. They ended up 3-2 losers and are the only ones yet to pick up a point after the opening two rounds. 

Lazio opened their season with a 2-0 loss to Como and needed a response sooner. They gave just that, in a resounding 4-0 win at home to Verona.

Last season, Lazio were among the strongest away teams, winning 11 of their 19 games in the league. Having started the current campaign with an away loss, they will hope to fix that as soon as possible.

It shouldn’t be a problem for Lazio, who are unbeaten in their last five matches against Sassuolo, winning four. The latest of their meetings ended in a draw, but Lazio won on their last two visits to Sassuolo.

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The Best Betting Odds for Sassuolo v Lazio Match

Bookmaker 1 X 2 Bonus up to
Bet365
3.6 3.6 2
Betfred
3.6 3.5 2.05
William Hill
3.5 3.4 1.95
Betway
3.6 3.5 2
Unibet
3.55 3.45 2.04
Check all Sassuolo vs Lazio odds
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What is the prediction for the football match between Sassuolo and Lazio?

Our prediction for the Sassuolo vs Lazio match is: Lazio wins the match.

Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 14/09/2025 between Sassuolo and Lazio in Serie A :

  • The Sportytrader ⭐ algorithm estimates a probability of 30.28% for a win of Sassuolo against Lazio with odds of 3.64 at 22bet.
  • The probability according to Sportytrader ⭐ for a draw between Sassuolo vs Lazio is 20.75% with odds of 3.64 at 22bet.
  • Our prediction model gives a 48.97% chance ⭐ for a win of Lazio vs Sassuolo with odds of 2.15 at 22bet.

Sassuolo vs Lazio Form

Sassuolo and Lazio's standings in the Serie A

Teams Pts P W D L GD
7
Lazio
Lazio
3 2 1 0 1 2
20
Sassuolo
Sassuolo
0 2 0 0 2 -3

Sassuolo and Lazio Last Matches

Sassuolo
Sassuolo Last matches
W D D W L L
Wins

2/6 (33%)

Draw

2/6 (33%)

Losses

2/6 (33%)

Average stats (Last 6 matchs)

2.17 Total goals
33% BTTS
1.17 Goals scored
1 Goals conceded
33% Over 2.5
67% Under 2.5

29 Aug 2025 - Serie A

Cremonese
3 :  2
Sassuolo

23 Aug 2025 - Serie A

Sassuolo
0 :  2
Napoli

15 Aug 2025 - Coppa Italia

Sassuolo
1 :  0
US Catanzaro

9 Aug 2025 - Clubs Friendlies

Brest
1 :  1
Sassuolo

5 Aug 2025 - Clubs Friendlies

Empoli
0 :  0
Sassuolo

23 Jul 2025 - Clubs Friendlies

Sassuolo
3 :  0
AC Trento
L L W W W L
Wins

3/6 (50%)

Draw

0/6 (0%)

Losses

3/6 (50%)

Average stats (Last 6 matchs)

2.33 Total goals
0% BTTS
1.5 Goals scored
0.83 Goals conceded
33% Over 2.5
67% Under 2.5

23 Aug 2025 - Serie A

Sassuolo
0 :  2
Napoli

15 Aug 2025 - Coppa Italia

Sassuolo
1 :  0
US Catanzaro

23 Jul 2025 - Clubs Friendlies

Sassuolo
3 :  0
AC Trento

15 Jul 2025 - Clubs Friendlies

Sassuolo
5 :  0
Real Vicenza

13 May 2025 - Serie B

Sassuolo
0 :  1
Frosinone

9 May 2025 - Serie B

Sassuolo
0 :  2
US Catanzaro
W W D D D L
Wins

2/6 (33%)

Draw

3/6 (50%)

Losses

1/6 (17%)

Average stats (Last 6 matchs)

2.5 Total goals
67% BTTS
1.5 Goals scored
1 Goals conceded
33% Over 2.5
67% Under 2.5

29 Aug 2025 - Serie A

Cremonese
3 :  2
Sassuolo

9 Aug 2025 - Clubs Friendlies

Brest
1 :  1
Sassuolo

5 Aug 2025 - Clubs Friendlies

Empoli
0 :  0
Sassuolo

4 May 2025 - Serie B

Cremonese
1 :  1
Sassuolo

25 Apr 2025 - Serie B

Cesena
0 :  2
Sassuolo

12 Apr 2025 - Serie B

Modena
1 :  3
Sassuolo
Lazio
Lazio Last matches
L D W W L W
Wins

3/6 (50%)

Draw

1/6 (17%)

Losses

2/6 (33%)

Average stats (Last 6 matchs)

2.33 Total goals
17% BTTS
1.5 Goals scored
0.83 Goals conceded
33% Over 2.5
67% Under 2.5

31 Aug 2025 - Serie A

Lazio
4 :  0
Hellas Verona

24 Aug 2025 - Serie A

Como 1907
2 :  0
Lazio

16 Aug 2025 - Clubs Friendlies

Lazio
2 :  0
Atromitos Athinon

9 Aug 2025 - Clubs Friendlies

Burnley
0 :  1
Lazio

2 Aug 2025 - Clubs Friendlies

Galatasaray
2 :  2
Lazio

30 Jul 2025 - Clubs Friendlies

Fenerbahce Istanbul
1 :  0
Lazio
D D L W W W
Wins

3/6 (50%)

Draw

2/6 (33%)

Losses

1/6 (17%)

Average stats (Last 6 matchs)

2.33 Total goals
33% BTTS
1.67 Goals scored
0.67 Goals conceded
33% Over 2.5
67% Under 2.5

31 Aug 2025 - Serie A

Lazio
4 :  0
Hellas Verona

16 Aug 2025 - Clubs Friendlies

Lazio
2 :  0
Atromitos Athinon

26 Jul 2025 - Clubs Friendlies

Lazio
1 :  0
Avellino

25 May 2025 - Serie A

Lazio
0 :  1
Lecce

10 May 2025 - Serie A

Lazio
1 :  1
Juventus

28 Apr 2025 - Serie A

Lazio
2 :  2
Parma
W D L D W L
Wins

2/6 (33%)

Draw

2/6 (33%)

Losses

2/6 (33%)

Average stats (Last 6 matchs)

2.17 Total goals
33% BTTS
1 Goals scored
1.17 Goals conceded
33% Over 2.5
67% Under 2.5

24 Aug 2025 - Serie A

Como 1907
2 :  0
Lazio

9 Aug 2025 - Clubs Friendlies

Burnley
0 :  1
Lazio

2 Aug 2025 - Clubs Friendlies

Galatasaray
2 :  2
Lazio

30 Jul 2025 - Clubs Friendlies

Fenerbahce Istanbul
1 :  0
Lazio

18 May 2025 - Serie A

Inter Milan
2 :  2
Lazio

4 May 2025 - Serie A

Empoli
0 :  1
Lazio

Sassuolo vs Lazio Stats: Head to Head (H2H)

Sassuolo

17 %

Draw

17 %

Lazio

67 %

Average stats (last H2H results)

2.33
Total goals
50%
BTTS
0.67
Goals scored (home team)
1.67
Goals scored (away team)
33%
Over 2.5
67%
Under 2.5

26 May 2024 - Serie A

Lazio
1 :  1
Sassuolo

21 Oct 2023 - Serie A

Sassuolo
0 :  2
Lazio

3 May 2023 - Serie A

Lazio
2 :  0
Sassuolo

15 Jan 2023 - Serie A

Sassuolo
0 :  2
Lazio

2 Apr 2022 - Serie A

Lazio
2 :  1
Sassuolo

12 Dec 2021 - Serie A

Sassuolo
2 :  1
Lazio
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Sassuolo vs Lazio last Lineups

Sassuolo

Formation : 4 - 3 - 3

49
A. Muric
6
S. Walukiewicz
21
J. Idzes
80
T. Muharemovic
3
J. Doig
40
A. Vranckx
18
N. Matic
11
D. Boloca
10
D. Berardi
99
A. Pinamonti
45
A. Lauriente
10
M. Zaccagni
11
T. Castellanos
22
M. Cancellieri
7
F. Dele-Bashiru
6
N. Rovella
8
M. Guendouzi
17
N. Tavares
25
O. Provstgaard
34
M. Gila
77
A. Marusic
94
I. Provedel

Formation : 4 - 3 - 3

Lazio

Missing players

Sassuolo
Sassuolo
Defender

C. Odenthal

Midfielder

K. Thorstvedt

Lazio
Lazio
Defender

Patric

S. Gigot

Midfielder

M. Lazzari

N. Rovella

M. Vecino

Forward

G. Isaksen

Most goals and assists

CD Huachipato Sassuolo
CD Huachipato Lazio
Top Goalscorer
Italy D. Berardi (1 Goals)
Italy A. Pinamonti (1 Goals)
Top Goalscorer
Italy M. Zaccagni (1 Goals) France M. Guendouzi (1 Goals) Argentina T. Castellanos (1 Goals) Senegal B. Dia (1 Goals)
Best assists
Italy C. Volpato (1 Assists)
Best assists
Argentina T. Castellanos (2 Assists)

Sassuolo - Lazio Key Points

  1. Lazio are unbeaten in five matches against Sassuolo.
  2. Lazio won on their last two visits to Sassuolo.
  3. Sassuolo are winless so far in the league.
  4. Sassuolo failed to score the last two times they hosted Lazio.
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Our Sassuolo vs Lazio Prediction

Lazio are the clear favorites going into this game, which they have not lost in their last five visits. They are coming off a comfortable win, recovering from their opening day defeat, and will be well motivated for this.

Meanwhile, they meet a host that’s under pressure and failed to win any of the last five meetings with Lazio. Sassuolo didn’t even score in their last two matches at home to Lazio. All these point to a comfortable outing for Lazio, and our prediction for Sassuolo v Lazio is that Lazio wins the match.

Prediction :

 

Lazio wins the match

 
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Sassuolo vs Lazio Prediction
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