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Manchester United vs Chelsea Prediction & Betting Tips - Premier League

England - Premier League

Manchester United
20/09/2025 11:30
Chelsea

Prediction :

 

Over 2.5 & BTTS

 
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 by Devesh Jaganath in Premier League Predictions

The Theatre of Dreams will convert to a canvas of contrasting colours and clashing ambitions when Chelsea arrive to take on Manchester United in the Premier League on Saturday afternoon. The Red Devils are in 14th place in the league standings, while the Blues are fifth after four games. Check out our match prediction below!

When Ruben Amorim walked in through the hallowed halls of Old Trafford in November, with him came fresh hope for the red half of Manchester. However, the Portuguese tactician’s tenure has been fraught with challenges so far, with his side finishing 15th last term - their worst-ever placement in the Prem - and languishing one point above the drop this season.   

In contrast, Enzo Maresca’s first season in West London was a remarkable one. Not only did the Italian steer his side to a top-four finish in the league, but he also oversaw their Conference League title run before winning the FIFA Club World Cup during the summer break. Can the hosts overcome the red mist, or will the visitors paint Old Trafford blue? Let’s get into the key stats!

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The Best Betting Odds for Manchester United v Chelsea Match

Bookmaker 1 X 2 Bonus up to
Bet365
2.7 3.8 2.38
Betfred
2.8 3.6 2.5
William Hill
2.7 3.5 2.4
Betway
2.7 3.6 2.4
Unibet
2.75 3.7 2.38
Check all Manchester United vs Chelsea odds
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What is the prediction for the football match between Manchester United and Chelsea?

Our prediction for the Manchester United vs Chelsea match is: over 2.5 & BTTS.

Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 20/09/2025 between Manchester United and Chelsea in Premier League :

  • The Sportytrader ⭐ algorithm estimates a probability of 35.92% for a win of Manchester United against Chelsea with odds of 2.81 at 22bet.
  • The probability according to Sportytrader ⭐ for a draw between Manchester United vs Chelsea is 27.19% with odds of 3.8 at Bet365.
  • Our prediction model gives a 36.89% chance ⭐ for a win of Chelsea vs Manchester United with odds of 2.5 at Betfred.

Manchester United vs Chelsea Form

Manchester United and Chelsea's standings in the Premier League

Teams Pts P W D L GD
5
Chelsea
Chelsea
8 4 2 2 0 6
14
Manchester United
Manchester United
4 4 1 1 2 -3

Manchester United and Chelsea Last Matches

Manchester United
Manchester United Last matches
D L D D W L
Wins

1/6 (17%)

Draw

3/6 (50%)

Losses

2/6 (33%)

Average stats (Last 6 matchs)

2.83 Total goals
67% BTTS
1.17 Goals scored
1.67 Goals conceded
50% Over 2.5
50% Under 2.5

14 Sep 2025 - Premier League

Manchester City
3 :  0
Manchester United

30 Aug 2025 - Premier League

Manchester United
3 :  2
Burnley

27 Aug 2025 - Carabao Cup

Grimsby Town
2 :  2
Manchester United

24 Aug 2025 - Premier League

Fulham
1 :  1
Manchester United

17 Aug 2025 - Premier League

Manchester United
0 :  1
Arsenal

9 Aug 2025 - Clubs Friendlies

Manchester United
1 :  1
Fiorentina
W W D D L W
Wins

3/6 (50%)

Draw

2/6 (33%)

Losses

1/6 (17%)

Average stats (Last 6 matchs)

3.33 Total goals
83% BTTS
2 Goals scored
1.33 Goals conceded
67% Over 2.5
33% Under 2.5

30 Aug 2025 - Premier League

Manchester United
3 :  2
Burnley

17 Aug 2025 - Premier League

Manchester United
0 :  1
Arsenal

9 Aug 2025 - Clubs Friendlies

Manchester United
1 :  1
Fiorentina

3 Aug 2025 - Clubs Friendlies

Manchester United
2 :  2
Everton

30 Jul 2025 - Clubs Friendlies

Manchester United
4 :  1
Bournemouth

26 Jul 2025 - Clubs Friendlies

Manchester United
2 :  1
West Ham
L L W D D L
Wins

1/6 (17%)

Draw

2/6 (33%)

Losses

3/6 (50%)

Average stats (Last 6 matchs)

2.5 Total goals
50% BTTS
1 Goals scored
1.5 Goals conceded
50% Over 2.5
50% Under 2.5

14 Sep 2025 - Premier League

Manchester City
3 :  0
Manchester United

27 Aug 2025 - Carabao Cup

Grimsby Town
2 :  2
Manchester United

24 Aug 2025 - Premier League

Fulham
1 :  1
Manchester United

30 May 2025 - Clubs Friendlies

Hong Kong
1 :  3
Manchester United

28 May 2025 - Clubs Friendlies

Asean All-Stars
1 :  0
Manchester United

21 May 2025 - Europa League

Tottenham
1 :  0
Manchester United
Chelsea
Chelsea Last matches
W D W W D L
Wins

3/6 (50%)

Draw

2/6 (33%)

Losses

1/6 (17%)

Average stats (Last 6 matchs)

3.5 Total goals
67% BTTS
2.33 Goals scored
1.17 Goals conceded
67% Over 2.5
33% Under 2.5

17 Sep 2025 - Champions League

Bayern Munich
3 :  1
Chelsea

13 Sep 2025 - Premier League

Brentford
2 :  2
Chelsea

30 Aug 2025 - Premier League

Chelsea
2 :  0
Fulham

22 Aug 2025 - Premier League

West Ham
1 :  5
Chelsea

17 Aug 2025 - Premier League

Chelsea
0 :  0
Crystal Palace

10 Aug 2025 - Clubs Friendlies

Chelsea
4 :  1
AC Milan
W W W W D W
Wins

5/6 (83%)

Draw

1/6 (17%)

Losses

0/6 (0%)

Average stats (Last 6 matchs)

2.33 Total goals
17% BTTS
2.17 Goals scored
0.17 Goals conceded
33% Over 2.5
67% Under 2.5

30 Aug 2025 - Premier League

Chelsea
2 :  0
Fulham

17 Aug 2025 - Premier League

Chelsea
0 :  0
Crystal Palace

10 Aug 2025 - Clubs Friendlies

Chelsea
4 :  1
AC Milan

8 Aug 2025 - Clubs Friendlies

Chelsea
2 :  0
Bayer Leverkusen

13 Jul 2025 - Club World Cup

Chelsea
3 :  0
PSG

16 Jun 2025 - Club World Cup

Chelsea
2 :  0
Los Angeles FC
W W L W D L
Wins

3/6 (50%)

Draw

1/6 (17%)

Losses

2/6 (33%)

Average stats (Last 6 matchs)

3.5 Total goals
67% BTTS
2 Goals scored
1.5 Goals conceded
67% Over 2.5
33% Under 2.5

17 Sep 2025 - Champions League

Bayern Munich
3 :  1
Chelsea

13 Sep 2025 - Premier League

Brentford
2 :  2
Chelsea

22 Aug 2025 - Premier League

West Ham
1 :  5
Chelsea

26 Jul 2025 - Clubs Friendlies

Sholing
2 :  0
Chelsea

8 Jul 2025 - Club World Cup

Fluminense
0 :  2
Chelsea

4 Jul 2025 - Club World Cup

Palmeiras
1 :  2
Chelsea

Manchester United vs Chelsea Stats: Head to Head (H2H)

Manchester United

33 %

Draw

33 %

Chelsea

33 %

Average stats (last H2H results)

3.33
Total goals
83%
BTTS
1.83
Goals scored (home team)
1.5
Goals scored (away team)
50%
Over 2.5
50%
Under 2.5

16 May 2025 - Premier League

Chelsea
1 :  0
Manchester United

3 Nov 2024 - Premier League

Manchester United
1 :  1
Chelsea

4 Apr 2024 - Premier League

Chelsea
4 :  3
Manchester United

6 Dec 2023 - Premier League

Manchester United
2 :  1
Chelsea

25 May 2023 - Premier League

Manchester United
4 :  1
Chelsea

22 Oct 2022 - Premier League

Chelsea
1 :  1
Manchester United
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Manchester United - Chelsea: Form Analysis

The gulf in class between the two Manchester clubs was made evident once again last weekend, when United suffered a 3-0 defeat at the hands of their noisy neighbours at the Etihad Stadium. 

The Red Devils' only victory this term so far came against newly promoted Burnley before the international break, while they were also dumped out of the EFL Cup by fourth-tier Grimsby Town. 

Perhaps the only real positive for the hosts at present is that they have the second-highest xG in the Prem this term (8.3). However, they also possess the fourth-highest xG against in the top flight. 

Man United won their last home game, but they have not won back-to-back in the Prem since December!

Meanwhile, Chelsea will be entering this match off the back of a tough trip to Bavaria in midweek, when they were beaten 3-1 by Bayern Munich in their Champions League opener. 

The Blues conceded in the third minute of stoppage time against Brentford last weekend, which forced them to settle for a 2-2 draw. However, they are one of only three teams still unbeaten in the division this term (W2 D2).

The visitors have only lost one of their last six away league games (W3 D2 L1), but they have not tasted victory at Old Trafford in the Prem in their last 12 visits, dating back to May 2013.

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Manchester United vs Chelsea last Lineups

Manchester United

Formation : 3 - 4 - 2 - 1

1
A. Bayindir
15
L. Yoro
4
M. De Ligt
3
N. Mazraoui
13
P. Dorgu
8
B. Fernandes
25
M. Ugarte
23
L. Shaw
16
A. Diallo
19
B. Mbeumo
30
B. Sesko
20
Joao Pedro
10
C. Palmer
8
E. Fernandez
7
P. Neto
25
M. Caicedo
24
R. James
3
M. Cucurella
23
T. Chalobah
4
T. Adarabioyo
27
M. Gusto
1
R. Sanchez

Formation : 4 - 2 - 3 - 1

Chelsea

Missing players

Manchester United
Manchester United
Defender

L. Martinez

D. Dalot

Midfielder

M. Mount

Forward

M. Cunha

Chelsea
Chelsea
Defender

L. Colwill

B. Badiashile

Midfielder

R. Lavia

D. Essugo

Forward

L. Delap

D. Fofana

Manchester United & Chelsea Squad Analysis

One of the biggest points of debate around Amorim’s tactics in recent times has been his use of a 3-4-3 formation, which the United boss reaffirmed is what he will stick to after the defeat to the Citizens. 

Amad Diallo was deployed as one of the number 10s, and Benjamin Sesko started as the spearhead of the attack in the Manchester Derby. However, that lineup could be shuffled again this week, with Matheus Cunha potentially set to return from injury. 

Mason Mount and Diogo Dalot were also sidelined for the trip to the Etihad, but reports in the lead-up suggest that both players could make the matchday squad this week. Lisandro Martinez is back on the grass, but he is still several weeks away from a full return. 

Can Cole Palmer score for Chelsea in a third match in succession?

The England international needed just five minutes to find the back of the net after coming on against the Bees last weekend, and he also netted the Blues' only goal against Bayern in midweek. 

Joao Pedro will be looking to add to the two goals and three assists he has already notched up this season. He also enjoys playing against this opponent, having scored three goals in his five matches against them in the Premier League. 

Pedro will almost certainly lead the line here with Liam Delap sidelined for the foreseeable future. Romeo Lavia and Dario Essugo are ruled out of this clash through injury, while Estevao is flagged as a major doubt. 

Most goals and assists

CD Huachipato Manchester United
CD Huachipato Chelsea
Top Goalscorer
Cameroon B. Mbeumo (2 Goals)
Top Goalscorer
Argentina E. Fernandez (2 Goals) Brazil Joao Pedro (2 Goals) Ecuador M. Caicedo (2 Goals) England C. Palmer (2 Goals)
Best assists
Portugal D. Dalot (1 Assists)
Best assists
Brazil Joao Pedro (3 Assists)

Manchester United and Chelsea Stats in Premier League

Manchester United
Manchester United
Chelsea
Chelsea
25%
Wins
50%
25%
Draw
50%
50%
Losses
0%
2.75
Total goals per match
3
1
Goals scored per match
2.25
1.75
Goals conceded per match
0.75
50%
Over 2.5
50%
50%
Under 2.5
50%
50%
BTTS
50%
0%
Clean Sheet
50%

Manchester United - Chelsea Key Points

  1. Each of Manchester United’s last three games have ended with over 2.5 goals.
  2. Manchester United have only kept one clean sheet in their last 11 league matches.
  3. Chelsea have scored two or more goals in each of their last three league games.
  4. Chelsea have only kept two clean sheets in their last 12 away league matches.
  5. Both teams scored in seven of the last eight matches between these sides.
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Our Manchester United vs Chelsea Prediction

While results have not gone Manchester United’s way so far this season, they have carried good attacking threat, ranked second for xG in the league, only behind Man City. That is a significant stat given they’ve already played two of last season’s top three teams. 

However, Chelsea have already scored a league-high nine goals this term, and have a fit and firing Cole Palmer back in the squad for this clash. The Blues will be looking to right the wrongs from their midweek defeat in Germany here, and we feel we will see a few goals in this one. Our Manchester United vs Chelsea prediction is over 2.5 & BTTS.  

Prediction :

 

Over 2.5 & BTTS

 
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Manchester United vs Chelsea - Other Interesting Predictions

Manchester United wins or draw

Odds 1.61

While Manchester United endured a difficult 2024-25 season and have started this campaign in mixed form, they have not lost to Chelsea at home in their last 12 Premier League encounters since 2013.

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Manchester United vs Chelsea match : Frequently asked questions

The Premier League match between Man United and Chelsea will take place on September 20 at 16:30 GMT. 

The Premier League match between Man United and Chelsea will be played at Old Trafford in Manchester.

The Premier League match between Man United and Chelsea will be broadcast live on Sky Sports in the UK.

Alternatively, you can keep up with all the action using our Premier League livescore tool.

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Manchester United vs Chelsea Prediction
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