Lyon Ou vs Newcastle Red Bulls Prediction & Betting Tips - Challenge Cup

Europe - Challenge Cup

Lyon Ou
06/12/2025 12:30
Newcastle Red Bulls

Prediction :

 

Lyon -16.5 handicap points

 
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 by Ita Emmanuel | in Challenge Cup Predictions

Last season's finalists, Lyon, open their 2025-26 Challenge Cup campaign welcoming Newcastle Red Bulls (formerly Newcastle Falcons) to Stade de Gerland on Saturday. Can the one-time champions edge the English side to kickstart their campaign on a winning note? Here is our prediction.

Lyon had a remarkable Challenge Cup campaign last season, dispatching Europe's best to reach the final. However, they fell short of what would have been their second Challenge Cup crown by losing 37-12 to Bath. 

They haven't impressed domestically this season, losing six of their 11 Top 14 matches. This includes a 22-20 loss to Aviron Bayonne last week, marking their fourth defeat in five league games. Nevertheless, Karim Ghezal's side remains clear favorites to ace this match. They have won four of their five home matches this season, and their most recent four Challenge Cup home fixtures. Newcastle Red Bulls couldn't scale past the Challenge Cup group-stage last season. They finished bottom of Group 2 with an ugly-looking 0-0-4 record. The Newcastle-based outfit are also struggling with a poor run of form in their domestic league campaign this season. They have lost all six of their league games and are rock bottom of the standings. 

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Lyon Ou v Newcastle Red Bulls Best Betting Odds

Bookmaker 1 X 2 Bonus up to
Melbet
1.05 46 10
Betwinner
1.05 46 10
Bet365
1.05 41 9
Roobet
1.09 50 6.6
BC Game
1.09 50 6.6
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Lyon Ou vs Newcastle Red Bulls Form

Lyon Ou and Newcastle Red Bulls Last Matches

Lyon Ou
Lyon Ou Last matches
W L L L W L
Wins

2/6 (33%)

Draw

0/6 (0%)

Losses

4/6 (67%)

29 Nov 2025 - Top 14

Aviron Bayonne
22 :  20
Lyon Ou

22 Nov 2025 - Top 14

Lyon Ou
43 :  24
Clermont

1 Nov 2025 - Top 14

RC Toulonnais
54 :  21
Lyon Ou

25 Oct 2025 - Top 14

Lyon Ou
19 :  36
Stade Rochelais

18 Oct 2025 - Top 14

Montpellier Herault Rugby
35 :  13
Lyon Ou

11 Oct 2025 - Top 14

Lyon Ou
44 :  19
USA Perpignan
L W W W L W
Wins

4/6 (67%)

Draw

0/6 (0%)

Losses

2/6 (33%)

22 Nov 2025 - Top 14

Lyon Ou
43 :  24
Clermont

25 Oct 2025 - Top 14

Lyon Ou
19 :  36
Stade Rochelais

11 Oct 2025 - Top 14

Lyon Ou
44 :  19
USA Perpignan

20 Sept 2025 - Top 14

Lyon Ou
42 :  37
Stade Francais Paris

6 Sept 2025 - Top 14

Lyon Ou
32 :  7
Racing 92

7 Jun 2025 - Top 14

Lyon Ou
34 :  47
Racing 92
W L L L L L
Wins

1/6 (17%)

Draw

0/6 (0%)

Losses

5/6 (83%)

29 Nov 2025 - Top 14

Aviron Bayonne
22 :  20
Lyon Ou

1 Nov 2025 - Top 14

RC Toulonnais
54 :  21
Lyon Ou

18 Oct 2025 - Top 14

Montpellier Herault Rugby
35 :  13
Lyon Ou

4 Oct 2025 - Top 14

Union Bordeaux Begles
32 :  20
Lyon Ou

27 Sept 2025 - Top 14

Section Paloise
40 :  15
Lyon Ou

13 Sept 2025 - Top 14

US Montalbanaise
18 :  25
Lyon Ou
Newcastle Red Bulls
Newcastle Red Bulls Last matches
L L L W L L
Wins

1/6 (17%)

Draw

0/6 (0%)

Losses

5/6 (83%)

28 Nov 2025 - PREM Rugby

Newcastle Red Bulls
17 :  39
Leicester Tigers

22 Nov 2025 - Premiership Rugby Cup

Saracens FC
43 :  0
Newcastle Red Bulls

15 Nov 2025 - Premiership Rugby Cup

Northampton Saints
14 :  31
Newcastle Red Bulls

31 Oct 2025 - Premiership Rugby Cup

Newcastle Red Bulls
8 :  10
Leicester Tigers

25 Oct 2025 - PREM Rugby

Harlequins FC
52 :  14
Newcastle Red Bulls

17 Oct 2025 - PREM Rugby

Newcastle Red Bulls
19 :  36
Northampton Saints
L W L L L L
Wins

1/6 (17%)

Draw

0/6 (0%)

Losses

5/6 (83%)

28 Nov 2025 - PREM Rugby

Newcastle Red Bulls
17 :  39
Leicester Tigers

31 Oct 2025 - Premiership Rugby Cup

Newcastle Red Bulls
8 :  10
Leicester Tigers

17 Oct 2025 - PREM Rugby

Newcastle Red Bulls
19 :  36
Northampton Saints

26 Sept 2025 - PREM Rugby

Newcastle Red Bulls
17 :  39
Saracens FC

12 Sept 2025 - Premiership Rugby Cup

Newcastle Red Bulls
26 :  14
Harlequins FC

16 May 2025 - PREM Rugby

Newcastle Red Bulls
12 :  26
Gloucester Rugby
L L L L W L
Wins

1/6 (17%)

Draw

0/6 (0%)

Losses

5/6 (83%)

22 Nov 2025 - Premiership Rugby Cup

Saracens FC
43 :  0
Newcastle Red Bulls

15 Nov 2025 - Premiership Rugby Cup

Northampton Saints
14 :  31
Newcastle Red Bulls

25 Oct 2025 - PREM Rugby

Harlequins FC
52 :  14
Newcastle Red Bulls

10 Oct 2025 - PREM Rugby

Sale Sharks
57 :  5
Newcastle Red Bulls

4 Oct 2025 - PREM Rugby

Exeter RC Chiefs
38 :  15
Newcastle Red Bulls

31 May 2025 - PREM Rugby

Leicester Tigers
42 :  20
Newcastle Red Bulls
Lyon Ou vs Newcastle Red Bulls Prediction

Players list

Lyon Ou
Lyon Ou
E. Dumortier D. Cretin T. Millet C. Cassang C. Chat S. Simmonds A. Botha J. Wainiqolo M. Meliande L. Allen I. Aptsiauri T. William J. Maraku A. Tchaptchet J. Rey
Newcastle Red Bulls
Newcastle Red Bulls
J. Hodgson A. Hearle M. McCallum B. Connon S. Arnold G. McGuigan E. Obatoyinbo E. Grayson H. Obatoyinbo S. Benitez Cruz C. Hancock A. Scott F. Lockwood O. Leatherbarrow T. Christie

Substitutes

Lyon Ou
Lyon Ou
F. Lambey C. Gomes Sa G. Marchand T. Moukoro B. Shvangiradze P. Jackson A. Deliance E. Gonzalez
Newcastle Red Bulls
Newcastle Red Bulls
J. Clark T. Cardall R. Palframan C. Wade B. Healy J. Elliott O. Fletcher R. Parsons

Lyon Ou - Newcastle Red Bulls Key Points

  1. Lyon have won four of their five home matches this season.
  2. Lyon have won their last four Challenge Cup home matches by double digits.
  3. Newcastle Red Bulls lost all their Challenge Cup group games last season.
  4. Newcastle Red Bulls have lost all their domestic league matches this season.
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Our Lyon Ou vs Newcastle Red Bulls Prediction

Lyon will look to stage another formidable showing in the Challenge Cup this term after narrowly falling short of the ultimate prize last season. Despite their poor start on the domestic scene, they remain among top favorites to win the competition and a winning start is non-negotiable. 

They have been formidable in their domestic and European home fixtures and are likely to comfortably ease past struggling Newcastle Red Bulls. Our Lyon vs Newcastle Red Bulls prediction is Lyon -16.5 handicap points.

Prediction :

 

Lyon -16.5 handicap points

 
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.