Flavio Cobolli vs Lorenzo Musetti Prediction & Betting Tips - ATP Lyon Open

ATP - ATP Lyon Open

Flavio Cobolli Italy
Flavio Cobolli ATP 6
24/10/2026 10:00
Lorenzo Musetti Italy
Lorenzo Musetti ATP 26

Prediction :

 

Flavio Cobolli wins

 
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 by Steve Ashfield | in Tennis Predictions

Top seed Flavio Cobolli is attempting to reach his fourth ATP Tour final of the year. He takes on fellow Italian sixth seeded Lorenzo Musetti in the semi-final of the indoor hard court Grand Prix Auvergne-Rhône Alpes in Lyon. Cobolli is the higher ranked player and should be fresher than Musetti, so our prediction is he wins.

Whoever wins will be up against either Taylor Fritz or Tommy Paul in the final.

Cobolli was in poor form before this tournament with four successive defeats. The Italian has rediscovered his form with two wins this week. After beating Stan Wawrinka in straight sets, he had a tougher quarter-final. Cobolli lost the opening set to fifth-seeded Brandon Nakashima, but recovered to win in three sets.

Lorenzo Musetti had a late night on Friday as he took three sets to get past Luca Van Assche in his quarter-final. The Italian played two tie-breaks in that match.

He had previously beaten Matteo Arnaldi and Moise Kouame in straight sets. He’s reached one final this year, that was in the outdoor hard court tournament played in Hong Kong. Before this tournament, Musetti had been beaten in three of his last four matches. 2025 saw him get to the final of the Athens indoor hard court tournament, losing to Novak Djokovic in three sets.

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Flavio Cobolli v Lorenzo Musetti Best Betting Odds

Bookmaker 1 2 Bonus
Stake
1.73 2.03
1xbet
1.79 2.01
Melbet
1.81 1.99
Betwinner
1.81 1.99
22bet
1.79 2.01
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Flavio Cobolli vs Lorenzo Musetti Form

Flavio Cobolli and Lorenzo Musetti Last Matches

Flavio Cobolli Last matches
W L L L W W
Wins

3/6 (50%)

Losses

3/6 (50%)

23 Oct 2026 - ATP Lyon Open

Flavio Cobolli
2 :  1
Brandon Nakashima

22 Oct 2026 - ATP Lyon Open

Flavio Cobolli
2 :  0
Stan Wawrinka

9 Oct 2026 - ATP Shanghai Masters

Adrian Mannarino
2 :  1
Flavio Cobolli

1 Oct 2026 - ATP Beijing Open

Roman Safiullin
2 :  0
Flavio Cobolli

5 Sept 2026 - ATP US Open

Alexander Blockx
3 :  1
Flavio Cobolli

3 Sept 2026 - ATP US Open

Tristan Schoolkate
1 :  3
Flavio Cobolli
Lorenzo Musetti Last matches
W L L W W W
Wins

4/6 (67%)

Losses

2/6 (33%)

23 Oct 2026 - ATP Lyon Open

Luca Van Assche
1 :  2
Lorenzo Musetti

21 Oct 2026 - ATP Lyon Open

Moise Kouame
0 :  2
Lorenzo Musetti

19 Oct 2026 - ATP Lyon Open

Matteo Arnaldi
0 :  2
Lorenzo Musetti

9 Oct 2026 - ATP Shanghai Masters

Yi Zhou
2 :  1
Lorenzo Musetti

3 Sept 2026 - ATP US Open

Dane Sweeny
3 :  1
Lorenzo Musetti

1 Sept 2026 - ATP US Open

Arthur Fery
0 :  3
Lorenzo Musetti
Flavio Cobolli vs Lorenzo Musetti Prediction

Flavio Cobolli - Lorenzo Musetti Key Points

  1. Cobolli is 21 places above his opponent in the live rankings.
  2. Only four players have earned more ranking points than Cobolli this year.
  3. Musetti had to go to three sets to win his quarter-final and had a late finish on Friday evening.
  4. Cobolli had a good win over fifth seed Brandon Nakashima in the last eight.
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Our Flavio Cobolli vs Lorenzo Musetti Prediction

We know that this year's Lyon final will be played between an Italian and an American. There are two semi-finals being played on Saturday between players from the same nation. This all-Italian clash can help Cobolli edge closer to confirming his place in the end-of-season Tour Finals.

He had a good three set win in the quarter-final over the always dangerous Brandon Nakashima. Lorenzo Musetti also had to go to a deciding set and had a late finish on Friday. Our Flavio Cobolli v Lorenzo Musetti prediction is Flavio Cobolli wins.

Prediction :

 

Flavio Cobolli wins

 
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.