Europe - Champions League
New customers only | Commercial content | 18+ age limit | T&Cs apply
by Thobelani Moyo | in Champions League Predictions
Ajax, one of two Dutch teams participating in the UEFA Champions League regular phase, are hoping for a bright start in matchday one. The hosts are set to welcome Inter Milan to the Johan Cruijff ArenA. Who will come out on top? Read on for our match prediction.
Ajax have been handed a formidable opponent in the opening match of the UEFA Champions League regular phase. Their opponents are Inter Milan. The Amsterdammers have nothing but revenge on their minds. They come into this match holding a long-past conflict. In the 2005-06 season, they suffered a 3-2 aggregate loss against this team in Round 16 of the UEFA Champions League.
Inter Milan secured their spot in the UEFA Champions League regular phase thanks to their second place in the previous Serie A season. They are a team that needs no introduction in this competition after reaching the final of this competition last season. However, it was a poor showing from them as they suffered a humiliating 5-0 defeat against Paris Saint-Germain.
Limited Offer. Currently at Stake
The Best Betting Odds for Ajax v Inter Milan Match
| Bookmaker | 1 | X | 2 | Bonus up to |
|---|---|---|---|---|
|
4.2 | 3.9 | 1.8 |
|
|
4.2 | 3.8 | 1.83 |
|
|
4 | 3.8 | 1.83 |
|
|
4 | 3.75 | 1.83 |
|
|
4.25 | 3.85 | 1.79 |
|
Limited Offer. Currently at Stake
What is the prediction for the football match between Ajax and Inter Milan?
Our prediction for the Ajax vs Inter Milan match is: both teams to score.
Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 17/09/2025 between Ajax and Inter Milan in Champions League :
- The Sportytrader ⭐ algorithm estimates a probability of 45.89% for a win of Ajax against Inter Milan with odds of 4.25 at Unibet.
- The probability according to Sportytrader ⭐ for a draw between Ajax vs Inter Milan is 25.81% with odds of 4.07 at 22bet.
- Our prediction model gives a 28.31% chance ⭐ for a win of Inter Milan vs Ajax with odds of 1.87 at 22bet.
Ajax vs Inter Milan Form
Ajax and Inter Milan's standings in the Champions League
| Teams | Pts | P | W | D | L | GD |
|---|---|---|---|---|---|---|
|
3
|
0 | 0 | 0 | 0 | 0 | 0 |
|
3
|
0 | 0 | 0 | 0 | 0 | 0 |
Ajax and Inter Milan Last Matches
3/6 (50%)
3/6 (50%)
0/6 (0%)
Average stats (Last 6 matchs)
13 Sep 2025 - Eredivisie
30 Aug 2025 - Eredivisie
24 Aug 2025 - Eredivisie
17 Aug 2025 - Eredivisie
10 Aug 2025 - Eredivisie
3 Aug 2025 - Clubs Friendlies
5/6 (83%)
1/6 (17%)
0/6 (0%)
Average stats (Last 6 matchs)
13 Sep 2025 - Eredivisie
24 Aug 2025 - Eredivisie
10 Aug 2025 - Eredivisie
3 Aug 2025 - Clubs Friendlies
24 Jul 2025 - Clubs Friendlies
19 Jul 2025 - Clubs Friendlies
1/6 (17%)
3/6 (50%)
2/6 (33%)
Average stats (Last 6 matchs)
30 Aug 2025 - Eredivisie
17 Aug 2025 - Eredivisie
27 Jul 2025 - Clubs Friendlies
14 May 2025 - Eredivisie
20 Apr 2025 - Eredivisie
13 Apr 2025 - Eredivisie
3/6 (50%)
1/6 (17%)
2/6 (33%)
Average stats (Last 6 matchs)
13 Sep 2025 - Serie A
31 Aug 2025 - Serie A
25 Aug 2025 - Serie A
16 Aug 2025 - Clubs Friendlies
12 Aug 2025 - Clubs Friendlies
8 Aug 2025 - Clubs Friendlies
4/6 (67%)
0/6 (0%)
2/6 (33%)
Average stats (Last 6 matchs)
31 Aug 2025 - Serie A
25 Aug 2025 - Serie A
16 Aug 2025 - Clubs Friendlies
30 Jun 2025 - Club World Cup
25 Jun 2025 - Club World Cup
21 Jun 2025 - Club World Cup
2/6 (33%)
2/6 (33%)
2/6 (33%)
Average stats (Last 6 matchs)
13 Sep 2025 - Serie A
12 Aug 2025 - Clubs Friendlies
8 Aug 2025 - Clubs Friendlies
17 Jun 2025 - Club World Cup
31 May 2025 - Champions League
23 May 2025 - Serie A
Ajax - Inter Milan: Form Analysis
Ajax are competing in the UEFA Champions League for the first time since the 2022-23 season. In the previous Eredivisie season, they managed to finish in second place, which was enough to see them secure a spot in this competition.
It has also been a convincing start to the current Eredivisie campaign. They have avoided defeat in their first five games, recording three wins and two draws. John Heitinga's charges had no mercy last time out in their league game against PEC Zwolle. In that match, they secured a 3-1 home victory.
Ajax are currenlty on a seven-match winless run against Italian opposition in UEFA club competitons.
Inter Milan have established itself as a force to be reckoned with in the UEFA Champions League. It was a bit unfortunate that they lost the final against Paris Saint-Germain, losing 5-0.
That result halted an eight-match unbeaten run that consisted of six wins and two draws. In light of that result, they have suffered just two defeats in their last 15 UEFA Champions League games.
Regarding their performance in the Serie A, it has not been the bright start they had hoped for. After winning the league opener by beating Torino 5-0 at home, nothing has gone according to plan. They have lost two consecutive matches, including a 4-3 defeat against Inter Milan on the road.
Limited Offer. Currently at Stake
Ajax vs Inter Milan last Lineups
Formation : 4 - 3 - 3
Formation : 3 - 4 - 3
Missing players
B. Van den Boomen
Ajax & Inter Milan Squad Analysis
Ajax have three players who are currently in the injury room heading into this clash. This includes Steven Berghuis, who is battling with health problems, Aaron Bouwman, who sustained an injury that is undisclosed at the moment, and long-term absentee Branco van den Boomen, who last sustained an injury in April due to a back injury.
Head coach John Heitinga is likely to select a 4-3-3 formation for this upcoming encounter against Inter Milan. Wout Weghorst is the current top goalscorer for the club in the Eredivisie with three goals. The 33-year-old is expected to lead the attack on Wednesday and get on the score sheet.
Marcus Thuram has been direclty involved in four goal contributions for Inter Milan this season.
Inter Milan are without their talisman, Lautaro Martinez, who was recently added to the injury room after the derby match against Juventus.
This means we could see Francesco Pio Esosito get the nod. The youngster will lead the attack with the influential Marcus Thuram, who is currently the top goal scorer in the Serie A. A 3-5-2 formation will be used in this upcoming encounter.
The back three will consist of Alessandro Bastoni, Francesco Acerbi, and Manuel Akanji, who are expected to keep the back door shut.
Most goals and assists
Ajax
Inter Milan
W. Weghorst
(3 Goals)
M. Thuram
(3 Goals)
S. Berghuis
(2 Assists)
L. Martinez
(1 Assists)
, 
A. Bastoni
(1 Assists)
, 
P. Sucic
(1 Assists)
,
M. Thuram
(1 Assists)
, 
P. Zielinski
(1 Assists)
,
F. Dimarco
(1 Assists)
, 
C. Augusto
(1 Assists)
,
N. Barella
(1 Assists)
Ajax - Inter Milan Key Points
- Ajax have seen both teams score in three of their last four matches.
- Inter Milan have conceded six goals in their last two competitive matches.
- Ajax and Inter Milan have seen both teams score in two of their last four meetings.
- Inter Milan have seen both teams score in each of their last two matches.
Limited Offer. Currently at Stake
Our Ajax vs Inter Milan Prediction
Ajax have been performing much better than Inter Milan, and it goes without a doubt that they come into this match boasting confidence. The home team has managed to score in each of their last five matches, and getting on the scoresheet here should be easy.
Inter Milan have shown some defensive vulnerabilities in their recent matches. Conceding six goals in two matches isn't a good display. However, they have shown signs of life in the final third, scoring nine goals in three outings. A high-scoring affair is expected in this one. Our Ajax vs Inter Milan prediction: both teams to score.
Ajax vs Inter Milan - Other Interesting Predictions
Marcus Thuram to score anytime
Use £/€50 free bets for the Ajax vs. Inter Milan game!
Are you planning to bet on the upcoming match between Ajax and Inter Milan? Why not take advantage of the free bets from Bet365? Use our promo code STYVIP1 and open your account. Bet365 offers a welcome package of €/£50 free bet credits if you bet €/£10 as a new player.
Try your luck on this year's Champions League! You need to make your qualifying bet of €/£10 within 30 days of opening an account and this can be on any sport with at least one selection priced at 1.2 (1/5) or bigger.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
Limited Offer. Currently at Stake
