Italy - Serie A
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by Sridhar Bhamidi | in Serie A Predictions
Inter Milan face their old nemesis Sassuolo on Sunday in a matchday four fixture of the 2025-26 Serie A campaign at San Siro. This match between the 11th-placed Nerazzurri (three points) and the 14th-placed Neroverdi (three points) comes with our prediction of both teams scoring goals.
It has been an indifferent start for both teams, who have just one win and two defeats, with Inter having a better goal difference. With both teams starting this round only two points above the relegation zone, the loser here will be under pressure after this weekend.
The hosts defeated Ajax 2-0 away from home in the midweek Champions League match. That result helped them make a comeback after losing their last two league games.
Those defeats came at home against Udinese (2-1) and away at Juventus (4-3) last weekend. These results have taken the sheen off their campaign, which started with a 5-0 win at San Siro against Torino on matchday one.
Sassuolo had a different trajectory in their season, defeating Lazio 1-0 at home last weekend. This result helped them overcome a poor start that saw them lose on the first two matchdays.
Matchday one loss at home against Napoli (2-0) was followed by a narrow 3-2 defeat at Cremonese, and this could be another close game.
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The Best Betting Odds for Inter Milan v Sassuolo Match
| Bookmaker | 1 | X | 2 | Bonus up to |
|---|---|---|---|---|
|
1.27 | 5.75 | 12 |
|
|
1.29 | 5.5 | 11 |
|
|
1.29 | 5.5 | 9.5 |
|
|
1.3 | 5.5 | 9 |
|
|
1.25 | 5.8 | 10.5 |
|
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What is the prediction for the football match between Inter Milan and Sassuolo?
Our prediction for the Inter Milan vs Sassuolo match is: both teams to score.
Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 21/09/2025 between Inter Milan and Sassuolo in Serie A :
- The Sportytrader ⭐ algorithm estimates a probability of 47.46% for a win of Inter Milan against Sassuolo with odds of 1.31 at 22bet.
- The probability according to Sportytrader ⭐ for a draw between Inter Milan vs Sassuolo is 19.89% with odds of 6.15 at 22bet.
- Our prediction model gives a 32.65% chance ⭐ for a win of Sassuolo vs Inter Milan with odds of 12 at Bet365.
Inter Milan vs Sassuolo Form
Inter Milan and Sassuolo's standings in the Serie A
| Teams | Pts | P | W | D | L | GD |
|---|---|---|---|---|---|---|
|
11
|
3 | 3 | 1 | 0 | 2 | 3 |
|
14
|
3 | 3 | 1 | 0 | 2 | -2 |
Inter Milan and Sassuolo Last Matches
3/6 (50%)
1/6 (17%)
2/6 (33%)
Average stats (Last 6 matchs)
17 Sep 2025 - Champions League
13 Sep 2025 - Serie A
31 Aug 2025 - Serie A
25 Aug 2025 - Serie A
16 Aug 2025 - Clubs Friendlies
12 Aug 2025 - Clubs Friendlies
4/6 (67%)
0/6 (0%)
2/6 (33%)
Average stats (Last 6 matchs)
31 Aug 2025 - Serie A
25 Aug 2025 - Serie A
16 Aug 2025 - Clubs Friendlies
30 Jun 2025 - Club World Cup
25 Jun 2025 - Club World Cup
21 Jun 2025 - Club World Cup
2/6 (33%)
2/6 (33%)
2/6 (33%)
Average stats (Last 6 matchs)
17 Sep 2025 - Champions League
13 Sep 2025 - Serie A
12 Aug 2025 - Clubs Friendlies
8 Aug 2025 - Clubs Friendlies
17 Jun 2025 - Club World Cup
31 May 2025 - Champions League
2/6 (33%)
2/6 (33%)
2/6 (33%)
Average stats (Last 6 matchs)
14 Sep 2025 - Serie A
29 Aug 2025 - Serie A
23 Aug 2025 - Serie A
15 Aug 2025 - Coppa Italia
9 Aug 2025 - Clubs Friendlies
5 Aug 2025 - Clubs Friendlies
4/6 (67%)
0/6 (0%)
2/6 (33%)
Average stats (Last 6 matchs)
14 Sep 2025 - Serie A
23 Aug 2025 - Serie A
15 Aug 2025 - Coppa Italia
23 Jul 2025 - Clubs Friendlies
15 Jul 2025 - Clubs Friendlies
13 May 2025 - Serie B
2/6 (33%)
3/6 (50%)
1/6 (17%)
Average stats (Last 6 matchs)
29 Aug 2025 - Serie A
9 Aug 2025 - Clubs Friendlies
5 Aug 2025 - Clubs Friendlies
4 May 2025 - Serie B
25 Apr 2025 - Serie B
12 Apr 2025 - Serie B
Inter Milan vs Sassuolo Stats: Head to Head (H2H)
50 %
0 %
50 %
Average stats (last H2H results)
4 May 2024 - Serie A
27 Sep 2023 - Serie A
13 May 2023 - Serie A
8 Oct 2022 - Serie A
20 Feb 2022 - Serie A
2 Oct 2021 - Serie A
Inter Milan vs Sassuolo last Lineups
Formation : 3 - 5 - 2
Formation : 4 - 3 - 3
Most goals and assists
Inter Milan
Sassuolo
M. Thuram
(5 Goals)
D. Berardi
(1 Goals)
,
A. Pinamonti
(1 Goals)
, 
A. Fadera
(1 Goals)
H. Calhanoglu
(2 Assists)
C. Volpato
(1 Assists)
, 
T. Muharemovic
(1 Assists)
Inter Milan and Sassuolo Stats in Serie A
Inter Milan - Sassuolo Key Points
- Inter’s last two Serie A games saw both teams score goals.
- In five of Inter’s last eight home league games, both teams scored goals.
- Six of Sassuolo’s last eight league fixtures returned goals from both teams.
- In five of Sassuolo’s last seven away league games saw both teams score goals.
- Three of the last four Serie A matches between Inter and Sassuolo saw goals from both teams.
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Our Inter Milan vs Sassuolo Prediction
It’s an open secret that Sassuolo is a banana peel fixture for Inter Milan. The Neroverdi won both seasonal games against the Nerazzurri last season, including a 2-1 win at San Siro. Inter’s form has been patchy this campaign, losing their recent two league fixtures. The win over Ajax got them back on track, but Sassuolo will look back at history and try to make this a tricky one for the hosts.
Sassuolo are likely to keep it competitive, and our Inter Milan vs Sassuolo prediction is both teams to score.
Use £/€50 free bets for the Inter Milan vs. Sassuolo game!
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
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