Daniil Medvedev vs Frances Tiafoe Prediction & Betting Tips - ATP US Open
ATP - ATP US Open
New customers only | Commercial content | 18+ age limit | T&Cs apply
by Steve Ashfield | in ATP US Open Predictions
The last 16 of the US Open sees seventh seed Daniil Medvedev face 11th-seeded Frances Tiafoe. Seven previous matches between these two players have been dominated by Medvedev. He leads Tiafoe 6-1 and our prediction is that the Russian can get another victory.
In the quarter-finals, the winner will be up against either 27th seed Tomas Martin Etcheverry or unseeded Alex Michelsen.
Daniil Medvedev won this outdoor hard court Grand Slam five years ago and has reached two other finals. Last year saw him lose in round one, but it's gone much better in 2026. Medvedev has had wins over Hugo Gaston, Sebastian Gorzny and 26th seed Arthur Rinderknech without losing a set.
A win will take him into his first Grand Slam quarter-final since this tournament two years ago.
Frances Tiafoe's sole win over Medvedev came on an indoor hard court. All the other six matches were played on this surface and won by Medvedev, including a win here in 2020. Their last meeting was in January 206 with Medvedev winning for the loss of only five games.
Tiafoe has twice reached the semi-finals of this tournament.
He struggled in the first round and needed to win the fourth and fifth sets to defeat Martin Damm. He's since had straight sets victories over Rei Sakamoto and 22nd seed Valentin Vacherot.
Limited Offer. Currently at Stake
Daniil Medvedev v Frances Tiafoe Best Betting Odds
| Bookmaker | 1 | 2 | Bonus up to |
|---|---|---|---|
|
|
1.6 | 2.21 |
|
|
|
1.64 | 2.31 |
|
|
|
1.63 | 2.29 |
|
|
|
1.63 | 2.29 |
|
|
|
1.62 | 2.3 |
|
Pre-register for our Member Area: win €500!
Who will win the Daniil Medvedev vs Frances Tiafoe Tennis game?
Our prediction for the Daniil Medvedev vs Frances Tiafoe match is: Daniil Medvedev wins.
The best winner predictions and betting odds for the Daniil Medvedev vs Frances Tiafoe game on 06/09/2026 of the current ATP US Open season:
- Daniil Medvedev has a 56.82% chance to win against Frances Tiafoe according to Shangrila ⭐ with the odds of 1.67.
- Frances Tiafoe has a 43.18% probability of winning facing Daniil Medvedev ⭐ with odds of 2.31 at 1xbet.
Daniil Medvedev vs Frances Tiafoe Best Prediction and Odds
Based on the bookmaker's betting lines in this match, Daniil Medvedev has a 56.82 % chance to win.
| Prediction | Chance to win |
|---|---|
| Daniil Medvedev | 56.82 % |
| Frances Tiafoe | 43.18 % |
Daniil Medvedev vs Frances Tiafoe Form
Daniil Medvedev and Frances Tiafoe Last Matches
4/6 (67%)
2/6 (33%)
4 Sept 2026 - ATP US Open
2 Sept 2026 - ATP US Open
30 Aug 2026 - ATP US Open
25 Aug 2026 - ATP Winston-Salem Open
18 Aug 2026 - ATP Cincinnati Open
16 Aug 2026 - ATP Cincinnati Open
5/6 (83%)
1/6 (17%)
4 Sept 2026 - ATP US Open
2 Sept 2026 - ATP US Open
31 Aug 2026 - ATP US Open
23 Aug 2026 - ATP Cincinnati Open
22 Aug 2026 - ATP Cincinnati Open
21 Aug 2026 - ATP Cincinnati Open
Daniil Medvedev vs Frances Tiafoe Stats: Head to Head (H2H)
100 %
0 %
6 Jan 2026 - Brisbane International
18 Mar 2023 - ATP Indian Wells
7 Sept 2020 - ATP US Open
Daniil Medvedev - Frances Tiafoe Key Points
- Medvedev is yet to lose a set in this tournament.
- Medvedev is a former champion here with two other finals reached.
- Medvedev has won all six of the previous outdoor hard court matches played between these two players.
- Tiafoe only won five games in his last loss to Medvedev seven months ago.
- Medvedev has won the last 11 sets played against Tiafoe on an outdoor hard court.
Limited Offer. Currently at Stake
Our Daniil Medvedev vs Frances Tiafoe Prediction
Frances Tiafoe needs to dramatically improve his form against Daniil Medvedev. The American has lost all six of their previous matches played on this surface with 11 sets in a row being lost. He only won five games when they played each other in Brisbane in January.
Daniil Medvedev has a great record in this tournament with one title won and two other appearances in finals. He has made it to the last 16 without dropping a single set. Our Daniil Medvedev v Frances Tiafoe prediction is Daniil Medvedev wins.
Use £/€50 free bets for the Daniil Medvedev vs. Frances Tiafoe game!

Are you planning to bet on the upcoming match between Daniil Medvedev and Frances Tiafoe? Why not take advantage of the free bets from Bet365? Use our promo code STYVIP1 and open your account. Bet365 offers a welcome package of €/£50 free bet credits if you bet €/£10 as a new player.
Try your luck on this year's ATP US Open! You need to make your qualifying bet of €/£10 within 30 days of opening an account and this can be on any sport with at least one selection priced at 1.2 (1/5) or bigger.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.