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Stefanos Tsitsipas vs Lorenzo Musetti Prediction & Betting Tips - ATP Vienna

ATP - ATP Vienna

ATP 25 Greece
Stefanos Tsitsipas
21/10/2025 11:30
ATP 8 Italy
Lorenzo Musetti

Prediction :

 

Over 22.5

 
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 by Steve Ashfield | in Tennis Predictions

Round one of the Erste Open in Vienna sees fourth seed Lorenzo Musetti take on unseeded Stefanos Tsitsipas. It's a tough draw for Musetti against a player who is still a threat despite dropping down the rankings. Here's our match prediction.

Lorenzo Musetti is eighth in both the live rankings and ATP Race. The Italian will want a good run in this indoor hard court tournament as he tries to qualify for the ATP Tour Finals. Last week saw him get to the quarter-finals in Brussels losing to Giovanni Mpetshi Perricard.

That was the fourth time in his last five tournaments that he's made it to at least the quarter-finals. His best recent run was a run to the final in Chengdu. This is his eighth match against Tsitipas and he trails 5-2. He lost their only hard court match played in 2021.

Stefanos Tsitsipas is 25th in the live rankings and four places lower in the ATP Race. He'd be a lot lower but for winning the Dubai tournament.The Greek is playing Musetti for the third time this year and lost both of their clay court matches but both saw over 22.5 games played.

Tsitsipas has lost four of his last six matches. We tip over 22.5 games to be played.

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The Best Betting Odds for Stefanos Tsitsipas v Lorenzo Musetti Match

Bookmaker 1 2 Bonus up to
Bet365
3.2 1.36
William Hill
2.9 1.4
Betway
3.2 1.35
Ladbrokes
3 1.35
Unibet
3.05 1.38
Check all Stefanos Tsitsipas vs Lorenzo Musetti odds

Who will win the Stefanos Tsitsipas vs Lorenzo Musetti Tennis game?

Our prediction for the Stefanos Tsitsipas vs Lorenzo Musetti match is: over 22.5 games to be played.

The best winner predictions and betting odds for the Stefanos Tsitsipas vs Lorenzo Musetti game on 21/10/2025 of the current ATP Vienna season:

  • Stefanos Tsitsipas has a 35.06% chance to win against Lorenzo Musetti according to 22bet ⭐ with the odds of 3.22.
  • Lorenzo Musetti has a 64.94% probability of winning facing Stefanos Tsitsipas ⭐ with odds of 1.52 at BC Game.

Stefanos Tsitsipas vs Lorenzo Musetti Best Prediction and Odds

Based on the bookmaker's betting lines in this match, Stefanos Tsitsipas has a 35.06 % chance to win.

PredictionChance to win
Stefanos Tsitsipas35.06 %
Lorenzo Musetti64.94 %

Stefanos Tsitsipas vs Lorenzo Musetti Form

Stefanos Tsitsipas and Lorenzo Musetti Last Matches

Stefanos Tsitsipas Last matches
W L L W L L
Wins

2/6 (33%)

Losses

4/6 (67%)

15 Oct 2025 - Six King Slam

Stefanos Tsitsipas
0 :  2
Jannik Sinner

28 Aug 2025 - ATP US Open

Stefanos Tsitsipas
2 :  3
Daniel Altmaier

26 Aug 2025 - ATP US Open

Stefanos Tsitsipas
3 :  1
Alexandre Muller

19 Aug 2025 - ATP Winston-Salem Open

Stefanos Tsitsipas
0 :  2
Yunchaokete Bu

11 Aug 2025 - ATP Cincinnati Open

Stefanos Tsitsipas
1 :  2
Benjamin Bonzi

9 Aug 2025 - ATP Cincinnati Open

Stefanos Tsitsipas
2 :  0
Fabian Marozsan
Lorenzo Musetti Last matches
L W W L W L
Wins

4/6 (67%)

Losses

2/6 (33%)

17 Oct 2025 - Brussels Open

Lorenzo Musetti
0 :  2
Giovanni Mpetshi Perricard

16 Oct 2025 - Brussels Open

Lorenzo Musetti
2 :  0
Yannick Hanfmann

8 Oct 2025 - ATP Shanghai Masters

Felix Auger Aliassime
2 :  0
Lorenzo Musetti

6 Oct 2025 - ATP Shanghai Masters

Luciano Darderi
0 :  2
Lorenzo Musetti

4 Oct 2025 - ATP Shanghai Masters

Francisco Comesana
0 :  2
Lorenzo Musetti

29 Sept 2025 - ATP Beijing Open

Learner Tien
abort
Lorenzo Musetti

Stefanos Tsitsipas vs Lorenzo Musetti Stats: Head to Head (H2H)

Stefanos Tsitsipas

67 %

Lorenzo Musetti

33 %

29 Apr 2025 - ATP Mutua Madrid Open

Stefanos Tsitsipas
0 :  2
Lorenzo Musetti

11 Apr 2025 - ATP Monte Carlo Masters

Lorenzo Musetti
2 :  1
Stefanos Tsitsipas

16 May 2023 - ATP Italian Open

Stefanos Tsitsipas
2 :  0
Lorenzo Musetti

22 Apr 2023 - ATP Barcelona

Lorenzo Musetti
1 :  2
Stefanos Tsitsipas

24 May 2022 - ATP French Open

Lorenzo Musetti
2 :  3
Stefanos Tsitsipas

22 May 2021 - ATP Lyon Open

Lorenzo Musetti
1 :  2
Stefanos Tsitsipas
Compare Stefanos Tsitsipas and Lorenzo Musetti with our comparison tool.

Stefanos Tsitsipas - Lorenzo Musetti Key Points

  1. Five of the last eight best-of-three matches played by Tsitsipas have seen over 22.5 games played.
  2. A 7-5 or 7-6 set would help our prediction. Tsitsipas has played at least one in five of his last seven matches.
  3. Over 22.5 games have been played in each of the last five best-of-three set matches played between Musetti and Tsitsipas.
  4. Three of Musetti's last five matches have had over 22.5 games played in them with five 7-5 or 7-6 sets.
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Our Stefanos Tsitsipas vs Lorenzo Musetti Prediction

Lorenzo Musetti has twice beaten Stefanos Tsitsipas this year. He bids for a hat-trick here but a first success on a hard court. This is an important couple of weeks for the Italian as he tries to qualify for the Tour Finals. He's in consistent form, continually going deep in tournaments.

Stefanos Tsitsipas won the Dubai tournament earlier this year but has struggled for consistency. He has had several wins over Musetti and some close matches. Our Stefanos Tsitsipas v Lorenzo Musetti prediction is over 22.5 games to be played.

Prediction :

 

Over 22.5

 
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Stefanos Tsitsipas vs Lorenzo Musetti Prediction

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