South America - Copa Libertadores
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by Nella Wagah | in Copa Libertadores Predictions
It is an even battle going into the Copa Libertadores last 16 return leg match pitting Brazilian giants Sao Paulo against Atletico Nacional. The two played to a 0-0 draw in the first leg in Colombia. Read on for our prediction of this one.
Hosts Sao Paulo will head into the game with the favorites’ feeling even though they are coming from two straight draws. The Brazilian side has six wins in the last 10 matches ahead of this encounter and lost only once in 10.
Recent outings have produced even better returns at home, with Sao Paulo coming up victorious in each of the last four. In Copa Libertadores at home they are unbeaten in seven.
Atletico Nacional also carry into this game a strong run of form. The Colombians are unbeaten in the last seven matches, though they have won just three.
After their 0-0 draw with Sao Paulo they played to a 2-2 draw with Fortaleza in their domestic league. That was the third time in four matches they scored more than a goal.
It was their seventh unbeaten outing, and they’ve also done well on the road, losing just once in the previous seven. Just like it was in the first leg, we expect this to be a well-balanced battle.
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The Best Betting Odds for SAO Paulo v Atlético Nacional Match
Bookmaker | 1 | X | 2 | Bonus up to |
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1.83 | 3.3 | 5 |
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1.83 | 3.1 | 4.6 |
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1.83 | 3.1 | 4.6 |
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1.83 | 3.3 | 4.5 |
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1.77 | 3.5 | 5 |
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What is the prediction for the football match between SAO Paulo and Atlético Nacional?
Our prediction for the SAO Paulo vs Atlético Nacional match is: draw.
Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 19/08/2025 between SAO Paulo and Atlético Nacional in Copa Libertadores :
- The Sportytrader ⭐ algorithm estimates a probability of 40.72% for a win of SAO Paulo against Atlético Nacional with odds of 1.85 at Tonybet.
- The probability according to Sportytrader ⭐ for a draw between SAO Paulo vs Atlético Nacional is 27.17% with odds of 3.5 at Unibet.
- Our prediction model gives a 32.11% chance ⭐ for a win of Atlético Nacional vs SAO Paulo with odds of 5.25 at Betobet.
SAO Paulo vs Atlético Nacional Form
SAO Paulo and Atlético Nacional Last Matches

3/6 (50%)
2/6 (33%)
1/6 (17%)
Average stats (Last 6 matchs)
16 Aug 2025 - Brasileirão Serie A
12 Aug 2025 - Copa Libertadores
9 Aug 2025 - Brasileirão Serie A
6 Aug 2025 - Copa do Brasil
3 Aug 2025 - Brasileirão Serie A
31 Jul 2025 - Copa do Brasil
5/6 (83%)
0/6 (0%)
1/6 (17%)
Average stats (Last 6 matchs)
9 Aug 2025 - Brasileirão Serie A
31 Jul 2025 - Copa do Brasil
27 Jul 2025 - Brasileirão Serie A
19 Jul 2025 - Brasileirão Serie A
12 Jun 2025 - Brasileirão Serie A
27 May 2025 - Copa Libertadores
2/6 (33%)
3/6 (50%)
1/6 (17%)
Average stats (Last 6 matchs)
16 Aug 2025 - Brasileirão Serie A
12 Aug 2025 - Copa Libertadores
6 Aug 2025 - Copa do Brasil
3 Aug 2025 - Brasileirão Serie A
24 Jul 2025 - Brasileirão Serie A
16 Jul 2025 - Brasileirão Serie A

3/6 (50%)
3/6 (50%)
0/6 (0%)
Average stats (Last 6 matchs)
16 Aug 2025 - Liga Postobon, Finalizacion
12 Aug 2025 - Copa Libertadores
8 Aug 2025 - Liga Postobon, Finalizacion
5 Aug 2025 - Copa Postobon, Knockout stage
2 Aug 2025 - Liga Postobon, Finalizacion
29 Jul 2025 - Copa Postobon, Knockout stage
3/6 (50%)
3/6 (50%)
0/6 (0%)
Average stats (Last 6 matchs)
16 Aug 2025 - Liga Postobon, Finalizacion
12 Aug 2025 - Copa Libertadores
8 Aug 2025 - Liga Postobon, Finalizacion
29 Jul 2025 - Copa Postobon, Knockout stage
25 Jul 2025 - Liga Postobon, Finalizacion
19 Jul 2025 - Liga Postobon, Finalizacion
4/6 (67%)
1/6 (17%)
1/6 (17%)
Average stats (Last 6 matchs)
5 Aug 2025 - Copa Postobon, Knockout stage
2 Aug 2025 - Liga Postobon, Finalizacion
22 Jul 2025 - Liga Postobon, Finalizacion
11 Jul 2025 - Liga Postobon, Finalizacion
19 Jun 2025 - Liga Postobon I, Group A
12 Jun 2025 - Liga Postobon I, Group A
SAO Paulo vs Atlético Nacional Stats: Head to Head (H2H)
12 Aug 2025 - Copa Libertadores
Most goals and assists









SAO Paulo and Atlético Nacional Stats in Copa Libertadores


SAO Paulo - Atlético Nacional Key Points
- Sao Paulo drew their last two matches.
- Atletico Nacional drew their last two games.
- Atletico won just four of 16 away matches.
- In their last four matches, Sao Paulo posted one win.
- Sao Paulo drew two of their last three Libertadores home matches.
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Our SAO Paulo vs Atlético Nacional Prediction
Atletico Nacional will look to restore their dominance in this fixture as they meet for the second time in nine years. Before the first leg, Nacional had beaten Sao Paulo three times in four meetings. Sao Paulo, however, won three of the four matches they hosted Nacional and will look to extend that.
Coming into this particular encounter, though, there is a high likelihood of the game proceeding into extra time. Our prediction for Sao Paulo v Atletico Nacional is for the match to end in a draw.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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