Inter Milan vs Shakhtar Donetsk Prediction & Betting Tips - Champions League
Europe - Champions League
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by Sridhar Bhamidi | in Champions League Predictions
Inter Milan are searching for their first points of the league phase of the UEFA Champions League (UCL) as they host an unbeaten Shakhtar Donetsk on matchday three. This match on Wednesday at San Siro between the 29th-placed ‘Nerazzurri’ and the 11th-placed ‘Miners’ could prove to be an intriguing battle for full points, but which side has the edge?
Inter are yet to win a point this season in the UCL competition, having lost to Real Madrid and Club Brugge. They have lost seven of their last eight UCL games (W1), including four in a row, so is the pressure mounting on the Milan giants?
Shakhtar won four points from their first two matchdays and could avoid defeat in their first three matchdays of a UCL campaign for only the second time in their history. Will the visitors script a new chapter in their European history, or will the hosts bounce back and keep their knockout hopes alive? Read more for our analysis, team news, and match predictions.
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Inter Milan v Shakhtar Donetsk Best Betting Odds
| Bookmaker | 1 | X | 2 | Bonus |
|---|---|---|---|---|
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1.18 | 7.80 | 12.00 |
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1.22 | 8.25 | 13.90 |
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|
1.17 | 7.90 | 13.00 |
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1.20 | 7.20 | 12.00 |
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1.17 | 7.90 | 13.00 |
|
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What is the prediction for the football match between Inter Milan and Shakhtar Donetsk?
Our prediction for the Inter Milan vs Shakhtar Donetsk match is: BTTS.
Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 21/10/2026 between Inter Milan and Shakhtar Donetsk in Champions League :
- The Sportytrader ⭐ algorithm estimates a probability of 47% for a win of Inter Milan against Shakhtar Donetsk with odds of 1.22 at 1xbet.
- The probability according to Sportytrader ⭐ for a draw between Inter Milan vs Shakhtar Donetsk is 15.08% with odds of 8.25 at 1xbet.
- Our prediction model gives a 37.91% chance ⭐ for a win of Shakhtar Donetsk vs Inter Milan with odds of 15 at Betsson.
Inter Milan vs Shakhtar Donetsk Form
Inter Milan and Shakhtar Donetsk's standings in the Champions League
| Teams | Pts | P | W | D | L | GD |
|---|---|---|---|---|---|---|
|
11
|
4 | 2 | 1 | 1 | 0 | +2 |
|
29
|
0 | 2 | 0 | 0 | 2 | -2 |
Inter Milan and Shakhtar Donetsk Last Matches
3/6 (50%)
1/6 (17%)
2/6 (33%)
Average stats (Last 6 matchs)
17 Oct 2026 - Serie A
13 Oct 2026 - Champions League
10 Oct 2026 - Serie A
19 Sept 2026 - Serie A
14 Sept 2026 - Serie A
8 Sept 2026 - Champions League
5/6 (83%)
0/6 (0%)
1/6 (17%)
Average stats (Last 6 matchs)
13 Oct 2026 - Champions League
10 Oct 2026 - Serie A
14 Sept 2026 - Serie A
5 Sept 2026 - Serie A
22 Aug 2026 - Serie A
15 Aug 2026 - Clubs Friendlies
3/6 (50%)
2/6 (33%)
1/6 (17%)
Average stats (Last 6 matchs)
17 Oct 2026 - Serie A
19 Sept 2026 - Serie A
8 Sept 2026 - Champions League
30 Aug 2026 - Serie A
8 Aug 2026 - Clubs Friendlies
5 Aug 2026 - Clubs Friendlies
6/6 (100%)
0/6 (0%)
0/6 (0%)
Average stats (Last 6 matchs)
17 Oct 2026 - Ukrainian Premier League
14 Oct 2026 - Champions League
9 Oct 2026 - Ukrainian Premier League
20 Sept 2026 - Ukrainian Premier League
17 Sept 2026 - Ukraine Cup
14 Sept 2026 - Ukrainian Premier League
5/6 (83%)
0/6 (0%)
1/6 (17%)
Average stats (Last 6 matchs)
17 Oct 2026 - Ukrainian Premier League
14 Oct 2026 - Champions League
20 Sept 2026 - Ukrainian Premier League
14 Sept 2026 - Ukrainian Premier League
29 Aug 2026 - Ukrainian Premier League
3 Aug 2026 - Ukrainian Premier League
5/6 (83%)
1/6 (17%)
0/6 (0%)
Average stats (Last 6 matchs)
9 Oct 2026 - Ukrainian Premier League
17 Sept 2026 - Ukraine Cup
10 Sept 2026 - Champions League
5 Sept 2026 - Ukrainian Premier League
16 Aug 2026 - Ukrainian Premier League
9 Aug 2026 - Ukrainian Premier League
Inter Milan vs Shakhtar Donetsk Stats: Head to Head (H2H)
40 %
60 %
0 %
Average stats (last H2H results)
24 Nov 2021 - Champions League
28 Sept 2021 - Champions League
9 Dec 2020 - Champions League
27 Oct 2020 - Champions League
17 Aug 2020 - Europa League
Inter Milan - Shakhtar Donetsk: Form Analysis
Inter won 3-1 away at Bologna last weekend to remain in charge of their fortunes in Serie A. That result also helped them bounce back from a 4-3 home defeat to Club Brugge on matchday two of the UCL. The Nerazzurri have now won only four of their last seven competitive games (D1, L2).
Both those defeats have come in the UCL competition, where they have now lost four in a row and have lost seven of their last eight UCL matches (W1).
Inter have lost their last four UCL games at home.
Shakhtar won 2-1 at home in the Ukrainian Premier League last weekend, making it a sixth victory in a row. That included a 3-1 home win over AEK Athens on matchday two, building on a 1-1 draw away at PSV Eindhoven on matchday one.
The Miners are in sparkling form this season, winning 10 of their 12 competitive matches (D1, L1), although their European form has been dire. They haven’t won any of their last seven away UCL proper games (D2, L5), leaving them cautious ahead of this trip.
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Players list
J. Martinez
DefenderY. Bisseck
M. Akanji
A. Bastoni
F. Dimarco
MidfielderN. Barella
P. Zielinski
P. Sucic
ForwardLuis Henrique
M. Thuram
F. Esposito
D. Riznyk
DefenderTobias
V. Bondar
A. Matturro
O. Karavaev
MidfielderD. Kryskiv
Y. Nazaryna
Isaque
ForwardBruninho
Luca Meirelles
P. Obah
Substitutes
R. Di Gennaro
I. Provedel
DefenderL. Bovio
C. Augusto
D. Spence
A. Stankovic
MidfielderH. Calhanoglu
H. Mkhitaryan
A. Diouf
ForwardA. Bonny
M. Mosconi
D. Tvardovskyi
DefenderPedro Henrique
M. Matvienko
MidfielderO. Ocheretko
M. Gomes
Gabriel Carvalho
G. Mendoza
V. Tsukanov
ForwardL. Traore
Alisson
K. Elias
Pedrinho
Missing players
B. Pavard
MidfielderC. Jones
ForwardL. Martinez
K. Fesiun
DefenderIrakli Azarov
A. Ghram
ForwardEguinaldo
Inter Milan & Shakhtar Donetsk Squad Analysis
Inter Milan’s forward Lautaro Martinez will be absent for this trip and is expected to miss at least a month. John Stones, Curtis Jones, and Benjamin Pavard are the other injury absences for the Nerazzurri.
The hosts are set to continue in their 3-5-2 formation with Marcus Thuram and Pio Esposito likely to partner up front. Thuram has four goals and two assists to his name in all competitions, while Carlos Augusto has three goals and two assists this season.
Gleiker Mendoza has scored in Shakhtar’s both league games this season.
The visitors don’t have too many absences for this trip, with Eguinaldo and Irakli Azarovi both ruled out for this crucial visit. A few regulars like Pedrinho and Pedro Henrique were rested at the weekend and could be back in action here.
Shakhtar are likely to line up in a 4-2-3-1 formation with Kaua Elias set to lead the line. He has three goals to his name in all competitions, while Isaque Silva has four assists this season, including one in the previous matchday.
Most goals and assists
Inter Milan
Shakhtar Donetsk
L. Martinez
(2 Goals)
G. Mendoza
(2 Goals)
L. Martinez
(1 Assists)
, 
A. Stankovic
(1 Assists)
, 
F. Dimarco
(1 Assists)
Isaque
(2 Assists)
Inter Milan and Shakhtar Donetsk Stats in Champions League
Inter Milan - Shakhtar Donetsk Key Points
- Seven of Inter’s last ten competitive matches have seen BTTS.
- Both teams scored in five of Inter’s last six matches.
- Shakhtar scored exactly 3 goals in five of their last six matches.
- Six of Shakhtar’s last seven away UCL matches produced goals from both teams.
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Our Inter Milan vs Shakhtar Donetsk Prediction
Defeats to Real Madrid and Club Brugge have put Inter in a tight spot because they can’t afford another defeat in this fixture if they need to keep their knockout hopes alive. Shakhtar have shown sparkling form all throughout this season, and will that be difficult for Inter to breach?
Inter have kept a clean sheet in each of their last five matches against Shakhtar, but all those have come between 2020 and 2021. Inter’s recent form suggests this could change, and our Inter Milan vs Shakhtar Donetsk prediction is BTTS.
Inter Milan vs Shakhtar Donetsk Alternative Predictions
Draw
Shakhtar are beaten just once in their last 12 competitive matches, but Inter’s two defeats out of two in this season’s UCL competition give them hope. Three of the last four head-to-head matches have ended in a draw, and the visitors could surprise with another stalemate here.
Federico Dimarco Over 0.5 Assists
Federico Dimarco looked to be at his best against Club Brugge for Inter, creating six chances, including providing an assist. He now has seven assists for Inter in the UCL and could be in line for another here. Back him to venture forward and grab an assist.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
