Europe - Champions League
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by Sridhar Bhamidi | in Champions League Predictions
Winless in the League phase of the 2025-26 UEFA Champions League competition, Bayer Leverkusen and PSV Eindhoven clash on Wednesday on matchday two. This match in Germany between these sides marks their first European meeting since 1994-95 and comes with our prediction of both teams scoring and over 2.5 goals scored.
Leverkusen seem to have stabilised their season, although they are not in the best of their form. Having steadily made their way up to sixth in the Bundesliga, the hosts will now eye redemption in the Champions League. Leaving it late on matchday one didn’t suit their purpose, and Leverkusen will hope to entertain their fans better this time.
PSV is better placed domestically than their hosts, but they face a greater need for points in Europe. Having been thumped on matchday one, anything less than a win here could be a catastrophe considering their difficult schedule ahead. Can the Dutch visitors rise to the occasion and surprise their hosts? Read more for our analysis, team news, and match predictions.
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The Best Betting Odds for Bayer Leverkusen v PSV Eindhoven Match
| Bookmaker | 1 | X | 2 | Bonus up to |
|---|---|---|---|---|
|
1.85 | 3.9 | 3.9 |
|
|
1.9 | 4 | 3.75 |
|
|
1.85 | 3.8 | 3.8 |
|
|
1.83 | 4 | 3.75 |
|
|
1.86 | 4 | 3.7 |
|
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What is the prediction for the football match between Bayer Leverkusen and PSV Eindhoven?
Our prediction for the Bayer Leverkusen vs PSV Eindhoven match is: over 2.5 and both teams to score.
Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 01/10/2025 between Bayer Leverkusen and PSV Eindhoven in Champions League :
- The Sportytrader ⭐ algorithm estimates a probability of 33.66% for a win of Bayer Leverkusen against PSV Eindhoven with odds of 1.9 at Betfred.
- The probability according to Sportytrader ⭐ for a draw between Bayer Leverkusen vs PSV Eindhoven is 16.47% with odds of 4.15 at 22bet.
- Our prediction model gives a 49.88% chance ⭐ for a win of PSV Eindhoven vs Bayer Leverkusen with odds of 4.1 at 22bet.
Bayer Leverkusen vs PSV Eindhoven Form
Bayer Leverkusen and PSV Eindhoven's standings in the Champions League
| Teams | Pts | P | W | D | L | GD |
|---|---|---|---|---|---|---|
|
17
|
1 | 1 | 0 | 1 | 0 | 0 |
|
29
|
0 | 1 | 0 | 0 | 1 | -2 |
Bayer Leverkusen and PSV Eindhoven Last Matches
2/6 (33%)
3/6 (50%)
1/6 (17%)
Average stats (Last 6 matchs)
27 Sep 2025 - Bundesliga
21 Sep 2025 - Bundesliga
18 Sep 2025 - Champions League
12 Sep 2025 - Bundesliga
30 Aug 2025 - Bundesliga
23 Aug 2025 - Bundesliga
3/6 (50%)
1/6 (17%)
2/6 (33%)
Average stats (Last 6 matchs)
21 Sep 2025 - Bundesliga
12 Sep 2025 - Bundesliga
23 Aug 2025 - Bundesliga
5 Aug 2025 - Clubs Friendlies
11 May 2025 - Bundesliga
26 Apr 2025 - Bundesliga
3/6 (50%)
2/6 (33%)
1/6 (17%)
Average stats (Last 6 matchs)
27 Sep 2025 - Bundesliga
18 Sep 2025 - Champions League
30 Aug 2025 - Bundesliga
15 Aug 2025 - DFB Pokal
8 Aug 2025 - Clubs Friendlies
1 Aug 2025 - Clubs Friendlies
3/6 (50%)
1/6 (17%)
2/6 (33%)
Average stats (Last 6 matchs)
27 Sep 2025 - Eredivisie
21 Sep 2025 - Eredivisie
16 Sep 2025 - Champions League
13 Sep 2025 - Eredivisie
30 Aug 2025 - Eredivisie
23 Aug 2025 - Eredivisie
3/6 (50%)
1/6 (17%)
2/6 (33%)
Average stats (Last 6 matchs)
21 Sep 2025 - Eredivisie
16 Sep 2025 - Champions League
30 Aug 2025 - Eredivisie
23 Aug 2025 - Eredivisie
9 Aug 2025 - Eredivisie
3 Aug 2025 - Johan Cruijff Schaal
6/6 (100%)
0/6 (0%)
0/6 (0%)
Average stats (Last 6 matchs)
27 Sep 2025 - Eredivisie
13 Sep 2025 - Eredivisie
17 Aug 2025 - Eredivisie
5 Jul 2025 - Clubs Friendlies
18 May 2025 - Eredivisie
11 May 2025 - Eredivisie
Bayer Leverkusen - PSV Eindhoven: Form Analysis
Leverkusen won 2-1 away at St Pauli last weekend in the Bundesliga to end a sequence of two draws in all competitions. It was also just their third win in the last seven competitive games (W3, D3, L1), indicating a need to close or start their games better.
No game emphasises this better than their matchday one 2-2 away draw at FC Copenhagen. They trailed the game for long periods and twice in the game came back from a goal down to draw, with the last goal coming in stoppage time.
Leverkusen’s last six competitive matches have all seen both teams score.
Eindhoven are also coming off a 2-1 away win over Excelsior in the Dutch Eredivisie, keeping them closer to the top spot. They still need some consistency in their game, as the visitors lost two of their five recent games in all competitions (W2, D1, L2).
It’s their away form that could be a challenge for them, as PSV have won just one of their recent five away matches in this competition (W1, D1, L3).
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Bayer Leverkusen vs PSV Eindhoven last Lineups
Formation : 3 - 4 - 2 - 1
Formation : 4 - 3 - 3
Missing players
E. Palacios
ForwardM. Terrier
W. Kuhn
K. Sildillia
ForwardA. Plea
R. van Bommel
M. Boadu
Bayer Leverkusen & PSV Eindhoven Squad Analysis
Leverkusen have been lining up in a 3-4-3 formation with the striker playing slightly ahead to make it look like a 3-4-2-1 system. They have a few injuries to worry about, as Robert Andrich and Patrik Schick were both injured on Saturday.
That could leave Christian Kofane as their lead striker, while right behind him Ezequiel Fernandez remains an injury concern. So does Nathan Tella, who missed their last three matches.
Leverkusen defender Alejandro Grimaldo has four goals and two assists this season.
PSV have been consistently playing in 4-3-3 formations, although with a slight tweak they were happy to make it look like a 4-2-3-1 system. It is on the injury front that the visitors have a lot to be worried about.
Ruben van Bommel, Alassane Plea, and Myron Boadu are all out of contention for PSV for different reasons. Sergino Dest is also doubtful, although the visitors expect him to be available here from the start. Their scoring hopes could revolve around midfielder Ismael Saibari’s form, as he scored once in their last two competitive matches.
Most goals and assists
Bayer Leverkusen
PSV Eindhoven
P. Schick
(4 Goals)
, 
A. Grimaldo
(4 Goals)
R. van Bommel
(4 Goals)
C. Kofane
(1 Assists)
, 
N. Tella
(1 Assists)
,
A. Grimaldo
(1 Assists)
I. Perisic
(5 Assists)
Bayer Leverkusen and PSV Eindhoven Stats in Champions League
Bayer Leverkusen - PSV Eindhoven Key Points
- Bayer Leverkusen saw both teams score goals in their last six competitive matches.
- Five of those six have seen over 2.5 goals scored.
- In six of their seven competitive matches this season, Leverkusen saw at least three goals scored.
- PSV saw both teams score goals in seven of their nine matches this season in all competitions.
- PSV have seen BTTS and over 2.5 goals scored in their last seven matches in European competitions.
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Our Bayer Leverkusen vs PSV Eindhoven Prediction
Leverkusen started their season in turmoil, having had to fire their coach Erik ten Hag, but have since settled into a rhythm. Even their matchday one draw result was a testimony of their ability to come back from difficult starts. Their matches have been entertaining, and that pattern could continue. PSV Eindhoven have followed the same template with their competitive matches this season, treating fans to goals.
That could continue here with both teams likely to go for goals. That’s why our Bayer Leverkusen vs PSV Eindhoven prediction is over 2.5 and both teams to score.
Bayer Leverkusen vs PSV Eindhoven - Other Interesting Predictions
Alejandro Grimaldo to score anytime
Alejandro Grimaldo scored for Leverkusen on matchday one and has three goals to his name in his last four competitive games, to go with one assist. The defender could once again be a surprise package for the home team.
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Bayer Leverkusen vs PSV Eindhoven match : Frequently asked questions
The Bayer Leverkusen vs PSV Eindhoven UEFA Champions League match is set to be shown on TNT Sports 1 in the UK. In Germany, the match is set to be broadcast live on DAZN, Amazon Prime and ZDF, while Ziggo Sport is the official broadcaster in the Netherlands.
You can follow the game through our live scores. Check out our UEFA Champions League Livescore page!
Let’s start with Bayer Leverkusen. They will next face – in that order – PSG (home), Benfica (away), Manchester City (away), Newcastle United (home), Olympiacos (away), and Villarreal (home).
PSV Eindhoven will play host to Napoli in the next round, followed by Olympiacos (away), Liverpool (away), Atletico Madrid (home), Newcastle United (away), and Bayern Munich (home).
This is the second season for the new format, as 36 teams start the League phase with four matches at home and four on the road. The top eight ranked teams from this phase will receive a bye to the round of 16. The teams ranked from 9th to 24th will play in the knockout phase play-offs. Among these, the teams from 9th to 16th are seeded, while the others are unseeded. Teams that are ranked from 25th to 36th will be eliminated from all eliminations, as no drop-down to the Europa League is on offer for the teams.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
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