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Reilly Opelka vs Francisco Comesana Prediction & Betting Tips - ATP Cincinnati Open

ATP - ATP Cincinnati Open

ATP 73 USA
Reilly Opelka
12/08/2025 10:00
ATP 71 Argentina
Francisco Comesana

Prediction :

 

Reilly Opelka to win in straight sets

 
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 by Steve Ashfield | in ATP Cincinnati Open Predictions

Two unseeded players meet in round three of the Cincinnati Open. Reilly Opelka caused a shock in the last round and now takes on Francisco Comesana. Who'll reach the last 16? Read our match prediction below.

Reilly Opelka has made it to round three of this outdoor hard court Masters event without dropping a set.  After beating Hugo Dellien, he defeated sixth seed Alex de Minaur 7-6 6-4. The winner of this match will face either Alexei Popyrin or ninth-seeded Andrey Rublev next.

Opelka has played either a 7-5 or 7-6 set in all but one of his last 22 matches on all surfaces. A side bet on one or more in this match could well win. The American is up to 65th in the live rankings.

Francisco Comesana is far more at home on clay and this is only his 12th hard court match in 2025. He has a 6-5 record but only in recent weeks has he been winning matches in main draws.

This week has seen him beat Jaume Munar and 29th seed Luciano Darderi. The latter saw his opponent retire in the second set when trailing 4-6 1-3. Those wins have taken Comesana to 62nd in the live rankings.

We tip Opelka to win in straight sets.

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The Best Betting Odds for Reilly Opelka v Francisco Comesana Match

Bookmaker 1 2 Bonus up to
Bet365
1.44 2.75
William Hill
1.44 2.75
Betway
1.45 2.75
Ladbrokes
1.48 2.6
Unibet
1.48 2.65
Check all Reilly Opelka vs Francisco Comesana odds
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Who will win the Reilly Opelka vs Francisco Comesana Tennis game?

Our prediction for the Reilly Opelka vs Francisco Comesana match is: Reilly Opelka to win in straight sets.

The best winner predictions and betting odds for the Reilly Opelka vs Francisco Comesana game on 12/08/2025 of the current ATP Cincinnati Open season:

  • Reilly Opelka has a 59.48% chance to win against Francisco Comesana according to Betobet ⭐ with the odds of 1.53.
  • Francisco Comesana has a 40.52% probability of winning facing Reilly Opelka ⭐ with odds of 2.75 at Bet365.

Reilly Opelka vs Francisco Comesana Best Prediction and Odds

Based on the bookmaker's betting lines in this match, Reilly Opelka has a 59.48 % chance to win.

PredictionChance to win
Reilly Opelka59.48 %
Francisco Comesana40.52 %

Reilly Opelka vs Francisco Comesana Form

Reilly Opelka and Francisco Comesana Last Matches

Reilly Opelka Last matches
L W W L W W
Wins

4/6 (67%)

Losses

2/6 (33%)

10 Aug 2025 - ATP Cincinnati Open

Alex De Minaur
0 :  2
Reilly Opelka

8 Aug 2025 - ATP Cincinnati Open

Hugo Dellien
0 :  2
Reilly Opelka

31 Jul 2025 - ATP Toronto

Learner Tien
2 :  0
Reilly Opelka

29 Jul 2025 - ATP Toronto

Reilly Opelka
2 :  1
Tomas Machac

27 Jul 2025 - ATP Toronto

Sebastian Ofner
0 :  2
Reilly Opelka

23 Jul 2025 - ATP Washington Citi Open

Daniil Medvedev
2 :  1
Reilly Opelka
Francisco Comesana Last matches
L W L W L W
Wins

3/6 (50%)

Losses

3/6 (50%)

10 Aug 2025 - ATP Cincinnati Open

Francisco Comesana
abort
Luciano Darderi

8 Aug 2025 - ATP Cincinnati Open

Francisco Comesana
2 :  0
Jaume Munar

30 Jul 2025 - ATP Toronto

Francisco Comesana
0 :  2
Alex De Minaur

28 Jul 2025 - ATP Toronto

Francisco Comesana
2 :  0
Damir Dzumhur

23 Jul 2025 - ATP Kitzbuhel Open

Francisco Comesana
0 :  2
Arthur Cazaux

21 Jul 2025 - ATP Kitzbuhel Open

Francisco Comesana
2 :  0
Tristan Boyer
Compare Reilly Opelka and Francisco Comesana with our comparison tool.

Reilly Opelka - Francisco Comesana Key Points

  1. Opelka beat sixth-seeded Alex de Minaur in the last round without dropping a set.
  2. Comesana played De Minaur in his last tourmanent and lost with only six games won.
  3. Opelka has reached one ATP Tour hard court final this year.
  4. Comesana hasn't won three successive ATP Tour main draw hard court matches in 2025.
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Our Reilly Opelka vs Francisco Comesana Prediction

Reilly Opelka is in good form at present and defeated sixth-seeded Alex de Minaur in round two. That's the de Minaur who comfortably beat Comesana in Toronto recently. Opelka continues to make life difficult for anyone who faces him with one of the best serves in the game.

Francisco Comesana has had two wins over players who like himself is far better on clay. Comesana is playing only his 12th hard court match of 2025, compared to 26 for Opelka. Our Reilly Opelka v Francisco Comesana prediction is Reilly Opelka to win in straight sets.

Prediction :

 

Reilly Opelka to win in straight sets

 
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When you place a bet on the match between Reilly Opelka and Francisco Comesana you can get a retirement guarantee with bet365. This means that your bet will be paid out as a winner if your opponent retires.

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Reilly Opelka vs Francisco Comesana Prediction
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