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21 November 2022 - 20:15 

USA - NFL

Arizona Cardinals
VS
San Francisco 49ers

Prediction :

49ers -8 point spread

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Arizona Cardinals vs San Francisco 49ers Prediction & Betting Tips - NFL

 by Joseph King | in NFL Prediction

Monday Night Football in the NFL sees a special Mexico edition at the Estadio Azteca in Mexico City with the San Francisco 49ers taking on the Arizona Cardinals. The Niners appear to be figuring things out after a difficult start to the season and have now moved above .500 following two straight wins to move to 5-4 on the year. They now trail the Seahawks by just one win as Seattle tops the NFC West with a 6-4 record following their bye week. The Cardinals were able to snap a two game losing streak last week but still sit just 4-6 on the year, good for third-place in the NFC West. 

Arizona Cardinals vs San Francisco 49ers Form

Arizona Cardinals and San Francisco 49ers's standings in the NFL

Teams % P W D L Series
5
San Francisco 49ers
San Francisco 49ers
0.765 17 13 0 4 10
30
Arizona Cardinals
Arizona Cardinals
0.235 17 4 0 13 -7

Arizona Cardinals and San Francisco 49ers Last Matches

Arizona Cardinals
Arizona Cardinals Last matches
W L L W L L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

13 Nov 2022 - NFL

Los Angeles Rams
17 :  27
Arizona Cardinals

6 Nov 2022 - NFL

Arizona Cardinals
21 :  31
Seattle Seahawks

26 Sep 2021 - NFL

Jacksonville Jaguars
19 :  31
Arizona Cardinals

3 Jan 2021 - NFL

Los Angeles Rams
18 :  7
Arizona Cardinals

6 Dec 2020 - NFL

Arizona Cardinals
28 :  38
Los Angeles Rams

25 Oct 2020 - NFL

Arizona Cardinals
37 :  34
Seattle Seahawks
San Francisco 49ers
San Francisco 49ers Last matches
L W W L L W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

13 Nov 2022 - NFL

San Francisco 49ers
22 :  16
Los Angeles Chargers

30 Oct 2022 - NFL

Los Angeles Rams
14 :  31
San Francisco 49ers

23 Oct 2022 - NFL

San Francisco 49ers
23 :  44
Kansas City Chiefs

3 Oct 2022 - NFL

San Francisco 49ers
24 :  9
Los Angeles Rams

30 Jan 2022 - NFL

Los Angeles Rams
20 :  17
San Francisco 49ers

22 Jan 2022 - NFL

Green Bay Packers
10 :  13
San Francisco 49ers

Arizona Cardinals - San Francisco 49ers: Form Analysis

The 49ers triumphed 22-16 in their win over the Chargers last week, holding superstar QB Justin Herbert to just 21/35 passing for 196 yards, a touchdown and an interception. It’s the San Francisco defense that has been the catalyst for their recent resurgence, although the offense has certainly been doing their part as well. The 49ers have now put up 53 points in their last two games with the often-criticized Jimmy Garoppolo stringing together a series of solid starts. The Cardinals defense, on the other hand, has been the exact opposite. Often unable to stop their opponents, Arizona has given up the most points in the division at 258.

Arizona Cardinals & San Francisco 49ers Squad Analysis

The acquisition of running back Chritian McCaffery has made this Niners’ team even more difficult to contain. Somewhat overlooked this season, San Fran has actually been quite productive moving the ball through the air, as they rank 10th in the NFL in passing yards per game. The defense steals the spotlight however, as this unit is truly elite and likely the best in the league at the moment. Kyler Murray returned to practice for the Cardinals and is expected to start this game but will likely be limited mobility-wise as he still appears to be suffering from his hamstring injury. This 49ers team is the last opponent he would have wanted to come up against and you can expect San Francisco to make things extremely difficult for the nimble young QB.

Arizona Cardinals - San Francisco 49ers Key Points

  1. The Niners pass offense is third in yards per play at 8.0.
  2. San Francisco’s defense ranks first in the NFL with the least average yards allowed per game at 280.6.
  3. The Cardinals defense ranks 23rd in total yards allowed per game at 357.6 and 30th in average points per game allowed at 25.8.
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Our Arizona Cardinals vs San Francisco 49ers Prediction

We’re going to back the San Francisco 49ers to get the win and cover the -8 point spread as our bet for this match. The Niners look to be entering a groove at the perfect time as we pass the midway mark in the season. They’ll now be looking to build up a few wins and overtake the Seahawks for the top spot in the division as they build towards the NFL Playoffs. A banged up Kyler Murray will likely be unable to do much against this extremely effective San Fran defense who could well have another big game as they look to hold the opposition to sub 17 points in their third consecutive game.

Prediction :

49ers -8 point spread

Exclusive Offer
$200 offered for betting!
Arizona Cardinals vs San Francisco 49ers Prediction

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