Manchester City vs Bayer Leverkusen Prediction & Betting Tips - Champions League
Europe - Champions League
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by Steve Ashfield | in Champions League Predictions
After another loss in the English Premier League, Manchester City will hope to get a win in Europe. The Citizens are fourth in the Champions League and on Tuesday are home to Bayer Leverkusen who are 21st in the table. Read our match prediction below.
City were beaten at Newcastle on Saturday again damaging their chances of regaining the English Premier League title. Their Champions League campaign has been going much better though and they are unbeaten after their first four matches of the league phase. After this match they have two away games, beginning with a trip to Real Madrid. A home win here is very much needed to stay in the top eight.
Bayer Leverkusen are four points adrift of the automatic qualification places for the last 16. Only one of their four games has been won in the league phase. They are second in the German Bundesliga, eight points behind Bayern Munich. Two of their final three games will be at home.
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Manchester City v Bayer Leverkusen Best Betting Odds
| Bookmaker | 1 | X | 2 | Bonus up to |
|---|---|---|---|---|
|
1.34 | 6 | 8 |
|
|
1.38 | 5 | 7.9 |
|
|
1.28 | 5.95 | 9.6 |
|
|
1.38 | 5 | 7.5 |
|
|
1.33 | 5.4 | 8.4 |
|
What is the prediction for the football match between Manchester City and Bayer Leverkusen?
Our prediction for the Manchester City vs Bayer Leverkusen match is: Manchester City wins and leads at half and full time.
Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 25/11/2025 between Manchester City and Bayer Leverkusen in Champions League :
- The Sportytrader ⭐ algorithm estimates a probability of 55.93% for a win of Manchester City against Bayer Leverkusen with odds of 1.38 at Melbet.
- The probability according to Sportytrader ⭐ for a draw between Manchester City vs Bayer Leverkusen is 5.41% with odds of 6.17 at 888Starz.
- Our prediction model gives a 38.66% chance ⭐ for a win of Bayer Leverkusen vs Manchester City with odds of 10 at 888Starz.
Manchester City - Bayer Leverkusen Prediction and Best Odds:
| Manchester City Bayer Leverkusen Prediction | Probability | Odds |
|---|---|---|
| Manchester City wins | 55.93% | 1.38 at Melbet |
| Over 2.5 goals | 70.91% | |
| Both Team To Score | 57.14% | |
| Half-time: Draw / Full-time: Manchester City | 24.35% | 4.33 at Bet365 |
Manchester City vs Bayer Leverkusen Form
Manchester City and Bayer Leverkusen's standings in the Champions League
| Teams | Pts | P | W | D | L | GD |
|---|---|---|---|---|---|---|
|
8
|
16 | 8 | 5 | 1 | 2 | +6 |
|
16
|
12 | 8 | 3 | 3 | 2 | -1 |
Manchester City and Bayer Leverkusen Last Matches
4/6 (67%)
0/6 (0%)
2/6 (33%)
Average stats (Last 6 matchs)
22 Nov 2025 - Premier League
9 Nov 2025 - Premier League
5 Nov 2025 - Champions League
2 Nov 2025 - Premier League
29 Oct 2025 - Carabao Cup
26 Oct 2025 - Premier League
6/6 (100%)
0/6 (0%)
0/6 (0%)
Average stats (Last 6 matchs)
9 Nov 2025 - Premier League
5 Nov 2025 - Champions League
2 Nov 2025 - Premier League
18 Oct 2025 - Premier League
27 Sept 2025 - Premier League
18 Sept 2025 - Champions League
3/6 (50%)
1/6 (17%)
2/6 (33%)
Average stats (Last 6 matchs)
22 Nov 2025 - Premier League
29 Oct 2025 - Carabao Cup
26 Oct 2025 - Premier League
21 Oct 2025 - Champions League
5 Oct 2025 - Premier League
1 Oct 2025 - Champions League
5/6 (83%)
0/6 (0%)
1/6 (17%)
Average stats (Last 6 matchs)
22 Nov 2025 - Bundesliga
8 Nov 2025 - Bundesliga
5 Nov 2025 - Champions League
1 Nov 2025 - Bundesliga
29 Oct 2025 - DFB Pokal
26 Oct 2025 - Bundesliga
3/6 (50%)
2/6 (33%)
1/6 (17%)
Average stats (Last 6 matchs)
8 Nov 2025 - Bundesliga
26 Oct 2025 - Bundesliga
21 Oct 2025 - Champions League
4 Oct 2025 - Bundesliga
1 Oct 2025 - Champions League
21 Sept 2025 - Bundesliga
5/6 (83%)
0/6 (0%)
1/6 (17%)
Average stats (Last 6 matchs)
22 Nov 2025 - Bundesliga
5 Nov 2025 - Champions League
1 Nov 2025 - Bundesliga
29 Oct 2025 - DFB Pokal
18 Oct 2025 - Bundesliga
27 Sept 2025 - Bundesliga
Manchester City - Bayer Leverkusen: Form Analysis
Manchester City are one of five clubs yet to lose a match in the league phase. Last season saw them lose in the last 16 of the Champions League and the Blues will certainly want to progress further this term.
City began their Champions League campaign with a 2-0 home win over Napoli. That was followed by a 2-2 draw in Monaco but they led twice and conceded a 90th minute equalizer. They got back into winning ways with a 2-0 win at Villarreal.
It's a tight battle for the automatic qualification places.
A 4-1 home win over Borussia Dortmund was another excellent result for City. They are only two points behind leaders Bayern Munich but just a point above ninth place, so can't afford any slip-ups like the 2-1 loss at Newcastle on Saturday.
Bayer Leverkusen have earned five points from their first four games in the league phase. They currently sit in the unseeded play-off positions but are only two points behind the seeded positions.
The German Bundesliga side have one victory in the league phase so far. That sole success came in their most recent game, winning 1-0 at Benfica. It was a much-needed victory after the heavy 7-2 home loss to PSG that had followed two opening draws.
At the weekend, they won 3-1 at Wolfsburg, their third successive win since losing 3-0 away to Bayern Munich.
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Manchester City against Bayer Leverkusen Lineups: Starting 11
Formation : 4 - 3 - 3
Formation : 3 - 4 - 2 - 1
Substitutes
G. Donnarumma
M. Bettinelli
DefenderJ. Gvardiol
N. OReilly
R. Dias
MidfielderM. Nunes
R. Cherki
P. Foden
B. Silva
ForwardJ. Doku
E. Haaland
J. Schlich
N. Lomb
DefenderF. Pohl
B. Hawighorst
MidfielderC. Echeverri
N. Mensah
J. Mensah
ForwardE. Ben Seghir
M. Culbreath
N. Tella
Missing players
L. Vazquez
MidfielderE. Palacios
E. Fernandez
A. Tape
Manchester City & Bayer Leverkusen Squad Analysis
The second half of the league phase gets underway on Tuesday. Manchester City look to be in a strong position but there is still plenty of work to do if they want to finish in the top eight. Just one point separates them from ninth-placed Galatasaray.
City lost at the weekend but didn't pick up any new injuries. Rodri remains doubtful for this game which is a blow in midfield. How will Guardiola react to the Newcastle loss? Some changes to their starting line-up are likely and they will hope Haaland rediscovers his scoring boots.
Injury and suspension problems for Bayer.
Bayer Leverkusen are only in the unseeded play-off positions. They will again be without midfielder Robert Andrich who is suspended. He was sent off in Leverkusen's 7-2 home loss to PSG. Leverkusen are short of midfielders and that bodes problems for them in this game.
Also suspended is defender Edmond Tapsoba. His absence should mean that England international Jarrell Quanash should start for the German Bundesliga side. Another problem is that Ibrahim Maza is doubtful after not coming out for the second half at Wolfsburg.
Most goals and assists
Manchester City
Bayer Leverkusen
E. Haaland
(8 Goals)
A. Grimaldo
(4 Goals)
, 
P. Schick
(4 Goals)
T. Reijnders
(3 Assists)
, 
J. Doku
(3 Assists)
A. Grimaldo
(3 Assists)
Manchester City - Bayer Leverkusen Key Points
- Manchester City are yet to lose in the league phase.
- Manchester City have won both of their home games in the Champions League this season.
- Bayer Leverkusen have only won one of their four league phase fixtures.
- Only five clubs have conceded more league phase goals than Leverkusen.
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Our Manchester City vs Bayer Leverkusen Prediction
Manchester City's form in the Champions League has been solid this season. Three of their four games have ended in victory and they really should have won their away game in Monaco to make it four. Both of their home games have been won with six goals scored.
Bayer Leverkusen only earned two points from their first three games and were hammered 7-2 at home by PSG. They breathed life back into their campaign with three points at Benfica. Our main Manchester City v Bayer Leverkusen prediction is Manchester City wins and leads at half and full time.
Manchester City vs Bayer Leverkusen Alternative Predictions
Erling Haaland to score the first goal
Last Minute: Pre-match odds analysis Manchester City Bayer Leverkusen
| Manchester City vs Bayer Leverkusen | Opening odds | Pre-match odds | Odds Movements |
|---|---|---|---|
| Manchester City wins | 1.44 | 1.38 | -4.2% |
| Draw | 4.92 | 6.17 | +25.4% |
| Bayer Leverkusen wins | 6.45 | 10 | +55.0% |
After kick-off, the latest odds movements show that:
- Manchester City is most likely to win
- The odds for this bet have decreased by 4.2% since opening
- The probability of this result was 69.4% and is now 72.5% (3.0%)
Manchester City vs Bayer Leverkusen - FAQs
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
