Portland Trail Blazers vs Detroit Pistons Prediction & Betting Tips - NBA

USA - NBA

Portland Trail Blazers
22/12/2025 21:00
Detroit Pistons

Prediction :

 

Detroit Pistons -4.5

 
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 by Thobelani Moyo | in NBA Predictions

The NBA cross-conference clash is upon us as the Portland Trail Blazers welcome the Detroit Pistons to the Moda Center on Monday. The Blazers are in tenth place in the Western Conference standings, while the Pistons lead the Eastern Conference. Here's our match prediction. 

For a team that had lost three straight games, it is fair to say the Portland Trail Blazers have started to find their rhythm with three consecutive wins. 

In their recent match, they faced the Kings at the Golden 1 Center and secured a 98-93 victory. Deni Avdija was the man of the moment as he led the team with a game-high 24 points while grabbing seven rebounds and dishing out 11 dimes.

The Blazers aim to get back to .500 at home with a win tonight. They've won five and lost six of their last 11 matches at the Moda Center. 

The Detroit Pistons have laid down a marker for the rest of this season, with their sights firmly set on the title after finishing sixth in the previous campaign. 

In their recent match, they secured a 112-86 home victory against the Charlotte Hornets. That result marked their fifth win in six games.

The Pistons have been impressive away from home and come into this clash boasting the best away record in the East. They've navigated 13 games and have won nine of those outings (L4).

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The Best Betting Odds for Portland Trail Blazers v Detroit Pistons Match

Bookmaker 1 2 Bonus up to
Bet365
2.95 1.42
William Hill
2.9 1.4
Unibet
2.88 1.44
Betway
3 1.43
Ladbrokes
2.9 1.4
Check all Portland Trail Blazers vs Detroit Pistons odds

Who will win the Portland Trail Blazers vs Detroit Pistons Basketball game?

Our prediction for the Portland Trail Blazers vs Detroit Pistons match is: Detroit Pistons -4.5.

The best winner predictions and betting odds for the Portland Trail Blazers vs Detroit Pistons game on 22/12/2025 of the current NBA season:

  • Portland Trail Blazers has a 36.47% chance to pick up the win against Detroit Pistons according to Tonybet ⭐ with the odds of 3.05.
  • There is a probability of 63.53% ⭐ for Detroit Pistons to win vs Portland Trail Blazers with odds of 1.44 at Unibet.

Portland Trail Blazers vs Detroit Pistons Form

Portland Trail Blazers and Detroit Pistons's standings in the NBA

Teams % P W L Series
1
Detroit Pistons
Detroit Pistons
0.786 28 22 6 1
10
Portland Trail Blazers
Portland Trail Blazers
0.429 28 12 16 3

Portland Trail Blazers and Detroit Pistons Last Matches

Portland Trail Blazers
Portland Trail Blazers Last matches
L L L W W W
Wins

3/6 (50%)

Losses

3/6 (50%)

20 Dec 2025 - NBA

Sacramento Kings
93 :  98
Portland Trail Blazers

18 Dec 2025 - NBA

Portland Trail Blazers
134 :  133
Sacramento Kings

14 Dec 2025 - NBA

Portland Trail Blazers
136 :  131
Golden State Warriors

11 Dec 2025 - NBA

New Orleans Pelicans
143 :  120
Portland Trail Blazers

7 Dec 2025 - NBA

Memphis Grizzlies
119 :  96
Portland Trail Blazers

5 Dec 2025 - NBA

Detroit Pistons
122 :  116
Portland Trail Blazers
L L L L W W
Wins

2/6 (33%)

Losses

4/6 (67%)

18 Dec 2025 - NBA

Portland Trail Blazers
134 :  133
Sacramento Kings

14 Dec 2025 - NBA

Portland Trail Blazers
136 :  131
Golden State Warriors

30 Nov 2025 - NBA

Portland Trail Blazers
115 :  123
Oklahoma City Thunder

26 Nov 2025 - NBA

Portland Trail Blazers
102 :  115
San Antonio Spurs

19 Nov 2025 - NBA

Portland Trail Blazers
121 :  122
Chicago Bulls

18 Nov 2025 - NBA

Portland Trail Blazers
110 :  127
Phoenix Suns
L W L L L W
Wins

2/6 (33%)

Losses

4/6 (67%)

20 Dec 2025 - NBA

Sacramento Kings
93 :  98
Portland Trail Blazers

11 Dec 2025 - NBA

New Orleans Pelicans
143 :  120
Portland Trail Blazers

7 Dec 2025 - NBA

Memphis Grizzlies
119 :  96
Portland Trail Blazers

5 Dec 2025 - NBA

Detroit Pistons
122 :  116
Portland Trail Blazers

3 Dec 2025 - NBA

Cleveland Cavaliers
110 :  122
Portland Trail Blazers

2 Dec 2025 - NBA

Toronto Raptors
121 :  118
Portland Trail Blazers
Detroit Pistons
Detroit Pistons Last matches
W W W W L W
Wins

5/6 (83%)

Losses

1/6 (17%)

20 Dec 2025 - NBA

Detroit Pistons
112 :  86
Charlotte Hornets

18 Dec 2025 - NBA

Dallas Mavericks
116 :  114
Detroit Pistons

15 Dec 2025 - NBA

Boston Celtics
105 :  112
Detroit Pistons

12 Dec 2025 - NBA

Detroit Pistons
142 :  115
Atlanta Hawks

6 Dec 2025 - NBA

Detroit Pistons
124 :  112
Milwaukee Bucks

5 Dec 2025 - NBA

Detroit Pistons
122 :  116
Portland Trail Blazers
L W W W W W
Wins

5/6 (83%)

Losses

1/6 (17%)

20 Dec 2025 - NBA

Detroit Pistons
112 :  86
Charlotte Hornets

12 Dec 2025 - NBA

Detroit Pistons
142 :  115
Atlanta Hawks

6 Dec 2025 - NBA

Detroit Pistons
124 :  112
Milwaukee Bucks

5 Dec 2025 - NBA

Detroit Pistons
122 :  116
Portland Trail Blazers

1 Dec 2025 - NBA

Detroit Pistons
99 :  98
Atlanta Hawks

28 Nov 2025 - NBA

Detroit Pistons
109 :  112
Orlando Magic
W L W L W L
Wins

3/6 (50%)

Losses

3/6 (50%)

18 Dec 2025 - NBA

Dallas Mavericks
116 :  114
Detroit Pistons

15 Dec 2025 - NBA

Boston Celtics
105 :  112
Detroit Pistons

3 Dec 2025 - NBA

Milwaukee Bucks
113 :  109
Detroit Pistons

29 Nov 2025 - NBA

Miami Heat
135 :  138
Detroit Pistons

26 Nov 2025 - NBA

Boston Celtics
117 :  114
Detroit Pistons

24 Nov 2025 - NBA

Indiana Pacers
117 :  122
Detroit Pistons

Portland Trail Blazers vs Detroit Pistons Stats: Head to Head (H2H)

Portland Trail Blazers

33 %

Detroit Pistons

67 %

5 Dec 2025 - NBA

Detroit Pistons
122 :  116
Portland Trail Blazers

9 Mar 2025 - NBA

Portland Trail Blazers
112 :  119
Detroit Pistons

6 Jan 2025 - NBA

Detroit Pistons
118 :  115
Portland Trail Blazers

8 Feb 2024 - NBA

Portland Trail Blazers
122 :  128
Detroit Pistons

1 Nov 2023 - NBA

Detroit Pistons
101 :  110
Portland Trail Blazers

21 Mar 2022 - NBA

Detroit Pistons
115 :  119
Portland Trail Blazers

Portland Trail Blazers - Detroit Pistons Key Points

  1. The Blazers have lost six of their last ten matches.
  2. The Pistons have covered the -4.5 point spread in five of their last six matches.
  3. The Blazers rank 29th in effective field goal (eFG%).
  4. The Pistons are 16-12 against the spread (ATS).
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Our Portland Trail Blazers vs Detroit Pistons Prediction

The Blazers are riding a wave of momentum, having won three consecutive matches. Facing the Pistons won't be an easy feat. They have lost five consecutive matches and failed to cover in their last two outings.

The Pistons are the best team in the East and boast the best away record. Admittedly, it hasn't been a great display on the road with three losses in their last five. Still, they should be able to secure a win here, having done so in their previous meeting, winning 122-116 at home. Our Portland Trail Blazers vs Detroit Pistons prediction: Detroit Pistons -4.5.

Prediction :

 

Detroit Pistons -4.5

 
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Portland Trail Blazers vs Detroit Pistons Prediction