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by Devesh Jaganath | in NBA Predictions
The Philadelphia 76ers will travel to Little Caesars Arena to face the Detroit Pistons in the NBA on Friday night. The Pistons (10-2) lead the Eastern Conference standings, while the Sixers (7-4) are in third place. Let’s get into the match prediction!
The Detroit Pistons have been excellent this season, currently holding the second-best record in the league, and now riding an eight-match win streak after beating the Bulls 124-113 on Wednesday.
The most impressive part about that victory was that the Pistons got the result without their star player Cade Cunningham as well as Jalen Duren. Duncan Robinson made seven threes en route to 23 points.
Detroit are 5-1 at home this season. Cunningham, Duren and Isaiah Stewart are listed as questionable, while Tobias Harris, Ausar Thompson and Jaden Ivey are sidelined.
Meanwhile, the Philadelphia 76ers have been in mixed form over the last two weeks, but they will be hoping to build up some momentum now after edging the Celtics 102-100 on Tuesday.
With Joel Embiid still not at his best, Tyrese Maxey has taken on the leadership role in this team and is averaging 33.2 PPG this season. Justin Edwards had his best game of the season against the C’s with 22 points.
The Sixers are 3-2 on the road this season, but they did lose to this opponent at home at the start of this week. Embiid and Paul George are ruled out for the visitors.
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The Best Betting Odds for Detroit Pistons v Philadelphia 76ers Match
| Bookmaker | 1 | 2 | Bonus up to |
|---|---|---|---|
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1.45 | 2.8 |
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1.44 | 2.75 |
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|
1.44 | 2.85 |
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1.44 | 2.8 |
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|
1.48 | 2.75 |
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Who will win the Detroit Pistons vs Philadelphia 76ers Basketball game?
Our prediction for the Detroit Pistons vs Philadelphia 76ers match is: Philadelphia 76ers +5.5.
The best winner predictions and betting odds for the Detroit Pistons vs Philadelphia 76ers game on 14/11/2025 of the current NBA season:
- Detroit Pistons has a 53.24% chance to pick up the win against Philadelphia 76ers according to Unibet ⭐ with the odds of 1.48.
- There is a probability of 46.76% ⭐ for Philadelphia 76ers to win vs Detroit Pistons with odds of 2.85 at Betway.
Detroit Pistons vs Philadelphia 76ers Form
Detroit Pistons and Philadelphia 76ers's standings in the NBA
| Teams | % | P | W | L | Series |
|---|---|---|---|---|---|
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1
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0.833 | 12 | 10 | 2 | 8 |
|
4
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0.636 | 11 | 7 | 4 | 1 |
Detroit Pistons and Philadelphia 76ers Last Matches
6/6 (100%)
0/6 (0%)
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5/6 (83%)
1/6 (17%)
12 Nov 2025 - NBA
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27 Oct 2025 - NBA
4/6 (67%)
2/6 (33%)
9 Nov 2025 - NBA
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24 Oct 2025 - NBA
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19 Jul 2025 - NBA Summer League
3/6 (50%)
3/6 (50%)
11 Nov 2025 - NBA
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5 Nov 2025 - NBA
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2 Nov 2025 - NBA
4/6 (67%)
2/6 (33%)
11 Nov 2025 - NBA
9 Nov 2025 - NBA
8 Nov 2025 - NBA
31 Oct 2025 - NBA
27 Oct 2025 - NBA
25 Oct 2025 - NBA
4/6 (67%)
2/6 (33%)
5 Nov 2025 - NBA
4 Nov 2025 - NBA
2 Nov 2025 - NBA
28 Oct 2025 - NBA
22 Oct 2025 - NBA
18 Jul 2025 - NBA Summer League
Detroit Pistons vs Philadelphia 76ers Stats: Head to Head (H2H)
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50 %
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15 Dec 2023 - NBA
Detroit Pistons - Philadelphia 76ers Key Points
- The 76ers have won seven of their last 10 games against this opponent.
- The 76ers have the best ATS rate in the NBA this season at 81.8% (9-2-0).
- The 76ers have covered the spread in four of their five away games this season.
- The team installed as the underdog has covered the spread in the last four games between these sides.
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Our Detroit Pistons vs Philadelphia 76ers Prediction
The Detroit Pistons have flown out the blocks this season, and despite missing a few key players, they are worthy favourites here, given they beat this opponent on the road earlier this week.
However, the Sixers have won seven of their last 10 against this opponent. They also covered in that match earlier this week and have only failed to cover the spread in two of their 11 games this season. Therefore, our Detroit Pistons vs Philadelphia 76ers prediction is Philadelphia 76ers +5.5.
If your team in the Detroit Pistons and Philadelphia 76ers game takes a 20-point lead, you win!
If you want to place a bet on the moneyline in the Detroit Pistons vs Philadelphia 76ers game, then bet365 is the place to do it. If the team that you have bet on takes a 20-point lead in the game, then bet365 will pay your bet out as a winner. If your team goes on to lose, you are still a winner.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
