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Arsenal vs Atletico Madrid Prediction & Betting Tips - Champions League

Europe - Champions League

Arsenal
21/10/2025 12:00
Atletico Madrid

Prediction :

 

Arsenal wins the match

 
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 by Devesh Jaganath in Champions League Predictions

The Emirates Stadium will transform into a theatre of tension when two titans of the game - Arsenal and Atletico Madrid - take to the turf for a tantalising Tuesday night clash in the Champions League. The Gunners are fifth in League Phase standings, while Los Colchoneros are in 10th place after the first two matchdays. Check out our match prediction below!

Mikel Arteta’s side have made an excellent start to their UCL campaign - two games, two wins, two clean sheets - the numbers back the buzz building in North London this season. After beating Athletic Bilbao on Matchday 1, Arsenal have now won each of their last six Champions League matches against Spanish opponents.

Diego Simeone’s side are well capable of dogged defensive displays, but that has not been the case over the first two gameweeks in this competition. The visitors lost to Liverpool during the opening week and have failed to win any of their last nine UCL group stage matches against English teams. Let’s get into the key stats!

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The Best Betting Odds for Arsenal v Atletico Madrid Match

Bookmaker 1 X 2 Bonus up to
Bet365
1.6 4.1 5.25
Betfred
1.53 3.75 6
William Hill
1.62 3.8 5
Betway
1.62 4 5.25
Unibet
1.56 4 6.1
Check all Arsenal vs Atletico Madrid odds
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What is the prediction for the football match between Arsenal and Atletico Madrid?

Our prediction for the Arsenal vs Atletico Madrid match is: Arsenal wins the match.

Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 21/10/2025 between Arsenal and Atletico Madrid in Champions League :

  • The Sportytrader ⭐ algorithm estimates a probability of 52.12% for a win of Arsenal against Atletico Madrid with odds of 1.66 at 22bet.
  • The probability according to Sportytrader ⭐ for a draw between Arsenal vs Atletico Madrid is 33.05% with odds of 4.19 at 888Starz.
  • Our prediction model gives a 14.83% chance ⭐ for a win of Atletico Madrid vs Arsenal with odds of 6.1 at Unibet.

Arsenal vs Atletico Madrid Form

Arsenal and Atletico Madrid's standings in the Champions League

Teams Pts P W D L GD
5
Arsenal
Arsenal
6 2 2 0 0 4
10
Atletico Madrid
Atletico Madrid
3 2 1 0 1 3

Arsenal and Atletico Madrid Last Matches

Arsenal
Arsenal Last matches
D W W W W W
Wins

5/6 (83%)

Draw

1/6 (17%)

Losses

0/6 (0%)

Average stats (Last 6 matchs)

2 Total goals
33% BTTS
1.67 Goals scored
0.33 Goals conceded
17% Over 2.5
83% Under 2.5

18 Oct 2025 - Premier League

Fulham
0 :  1
Arsenal

4 Oct 2025 - Premier League

Arsenal
2 :  0
West Ham

1 Oct 2025 - Champions League

Arsenal
2 :  0
Olympiacos

28 Sep 2025 - Premier League

Newcastle
1 :  2
Arsenal

24 Sep 2025 - Carabao Cup

Port Vale
0 :  2
Arsenal

21 Sep 2025 - Premier League

Arsenal
1 :  1
Manchester City
W W W D W W
Wins

5/6 (83%)

Draw

1/6 (17%)

Losses

0/6 (0%)

Average stats (Last 6 matchs)

2.83 Total goals
17% BTTS
2.67 Goals scored
0.17 Goals conceded
50% Over 2.5
50% Under 2.5

4 Oct 2025 - Premier League

Arsenal
2 :  0
West Ham

1 Oct 2025 - Champions League

Arsenal
2 :  0
Olympiacos

21 Sep 2025 - Premier League

Arsenal
1 :  1
Manchester City

13 Sep 2025 - Premier League

Arsenal
3 :  0
Nottingham Forest

23 Aug 2025 - Premier League

Arsenal
5 :  0
Leeds

9 Aug 2025 - Emirates Cup

Arsenal
3 :  0
Athletic Bilbao
W L W W W W
Wins

5/6 (83%)

Draw

0/6 (0%)

Losses

1/6 (17%)

Average stats (Last 6 matchs)

1.67 Total goals
17% BTTS
1.33 Goals scored
0.33 Goals conceded
17% Over 2.5
83% Under 2.5

18 Oct 2025 - Premier League

Fulham
0 :  1
Arsenal

28 Sep 2025 - Premier League

Newcastle
1 :  2
Arsenal

24 Sep 2025 - Carabao Cup

Port Vale
0 :  2
Arsenal

16 Sep 2025 - Champions League

Athletic Bilbao
0 :  2
Arsenal

31 Aug 2025 - Premier League

Liverpool
1 :  0
Arsenal

17 Aug 2025 - Premier League

Manchester United
0 :  1
Arsenal
Atletico Madrid
Atletico Madrid Last matches
W W W D D W
Wins

4/6 (67%)

Draw

2/6 (33%)

Losses

0/6 (0%)

Average stats (Last 6 matchs)

3.83 Total goals
83% BTTS
2.67 Goals scored
1.17 Goals conceded
50% Over 2.5
50% Under 2.5

18 Oct 2025 - LaLiga

Atletico Madrid
1 :  0
Osasuna

10 Oct 2025 - Clubs Friendlies

Atletico Madrid
1 :  1
Inter Milan

5 Oct 2025 - LaLiga

Celta Vigo
1 :  1
Atletico Madrid

30 Sep 2025 - Champions League

Atletico Madrid
5 :  1
Eintracht Frankfurt

27 Sep 2025 - LaLiga

Atletico Madrid
5 :  2
Real Madrid

24 Sep 2025 - LaLiga

Atletico Madrid
3 :  2
Rayo Vallecano
W W W W D W
Wins

5/6 (83%)

Draw

1/6 (17%)

Losses

0/6 (0%)

Average stats (Last 6 matchs)

3.83 Total goals
67% BTTS
2.83 Goals scored
1 Goals conceded
50% Over 2.5
50% Under 2.5

18 Oct 2025 - LaLiga

Atletico Madrid
1 :  0
Osasuna

10 Oct 2025 - Clubs Friendlies

Atletico Madrid
1 :  1
Inter Milan

30 Sep 2025 - Champions League

Atletico Madrid
5 :  1
Eintracht Frankfurt

27 Sep 2025 - LaLiga

Atletico Madrid
5 :  2
Real Madrid

24 Sep 2025 - LaLiga

Atletico Madrid
3 :  2
Rayo Vallecano

13 Sep 2025 - LaLiga

Atletico Madrid
2 :  0
Villarreal
W L D L D D
Wins

1/6 (17%)

Draw

3/6 (50%)

Losses

2/6 (33%)

Average stats (Last 6 matchs)

2.67 Total goals
83% BTTS
1.33 Goals scored
1.33 Goals conceded
33% Over 2.5
67% Under 2.5

5 Oct 2025 - LaLiga

Celta Vigo
1 :  1
Atletico Madrid

21 Sep 2025 - LaLiga

Mallorca
1 :  1
Atletico Madrid

17 Sep 2025 - Champions League

Liverpool
3 :  2
Atletico Madrid

30 Aug 2025 - LaLiga

Alavés
1 :  1
Atletico Madrid

17 Aug 2025 - LaLiga

Espanyol
2 :  1
Atletico Madrid

9 Aug 2025 - Clubs Friendlies

Newcastle
0 :  2
Atletico Madrid

Arsenal vs Atletico Madrid Stats: Head to Head (H2H)

Arsenal

0 %

Draw

67 %

Atletico Madrid

33 %

Average stats (last H2H results)

1.67
Total goals
67%
BTTS
0.67
Goals scored (home team)
1
Goals scored (away team)
0%
Over 2.5
100%
Under 2.5

26 Jul 2018 - International Champions Cup

Atletico Madrid
1 :  1
Arsenal

3 May 2018 - Europa League

Atletico Madrid
1 :  0
Arsenal

26 Apr 2018 - Europa League

Arsenal
1 :  1
Atletico Madrid
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Arsenal - Atletico Madrid: Form Analysis

Arsenal will be looking to extend their perfect record in Europe’s top-tier club competition here, following back-to-back 2-0 victories against Bilbao and Olympiacos over the first two matchdays. 

After a solid 1-0 victory over Fulham at the weekend, the Gunners are now riding a five-match win streak and are unbeaten in their last eight games across all competitions, dating back to the end of August. 

The hosts have won each of their last 14 group-stage home games in UEFA competitions and have kept 11 consecutive clean sheets in such matches leading up to this blockbuster fixture. 

Arsenal is the only team in UCL history to win six in a row against Spanish opposition!

Meanwhile, Atletico Madrid kicked off their European campaign with a 3-2 defeat to Liverpool, but they bounced back in style, thumping Bundesliga outfit Eintracht Frankfurt 5-1 on Matchday 2. 

While Los Rojibalncos’ defence has been questionable, they are the second-highest goal scorers in this competition (7) and have only failed to find the net in one of their last 18 UCL matches. 

However, the visitors away form has been poor this season, as they have not won a single game on the road across all competitions in 2025-26. Their last away win in the Champions League came in January against Salzburg. 

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Arsenal vs Atletico Madrid last Lineups

Arsenal

Formation : 4 - 3 - 3

1
D. Raya
12
J. Timber
2
W. Saliba
6
G. Magalhaes
33
R. Calafiori
10
E. Eze
36
M. Zubimendi
41
D. Rice
7
B. Saka
14
V. Gyokeres
19
L. Trossard
19
J. Alvarez
7
A. Griezmann
23
N. Gonzalez
6
Koke
8
B. Pablo
10
A. Baena
17
D. Hancko
24
R. Le Normand
2
J. Gimenez
14
M. Llorente
13
J. Oblak

Formation : 4 - 4 - 2

Atletico Madrid

Missing players

Arsenal
Arsenal
Defender

P. Hincapie

Midfielder

M. Odegaard

Forward

G. Jesus

K. Havertz

N. Madueke

Atletico Madrid
Atletico Madrid
Midfielder

J. Cardoso

Arsenal & Atletico Madrid Squad Analysis

Arsenal came away from Craven Cottage with no new injury concerns, but they are still without the services of Piero Hincapie, Noni Madueke, Kai Havertz, Gabriel Jesus and skipper Martin Odegaard.

Martin Zubimendi and Declan Rice are both walking tightropes after being cautioned against Olympiacos, but Arteta will likely take the risk and start the midfield duo, given that their next match is against Slavia Prague. 

Bukayo Saka should also start this one after coming off the bench to net the Gunners' second goal on Matchday 2, which took his tally to 11 goals in 19 Champions League matches. 

Julian Alvarez has scored seven goals in his last seven UCL matches!

With three goal involvements, Alvarez was the standout performer against Frankfurt, but he never managed to score against this opponent in his four previous appearances against them for Man City. 

Atleti’s victory over Osasuna at the weekend came at a cost, with Nico Gonzalez sustaining a head injury which will keep him sidelined for this match. Simeone is likely to call upon his son, Giuliano, to replace Gonzalez in the visitors’ engine room. 

Ilias Kostis and Johnny Cardoso are ruled out this week through injury. Clement Lenglet is likely to return to the starting 11 after missing the victory over the weekend due to suspension.

Most goals and assists

CD Huachipato Arsenal
CD Huachipato Atletico Madrid
Top Goalscorer
Brazil G. Martinelli (3 Goals)
Belgium L. Trossard (3 Goals)
England B. Saka (3 Goals)
Sweden V. Gyokeres (3 Goals)
Top Goalscorer
Argentina J. Alvarez (7 Goals)
Best assists
England D. Rice (2 Assists)
Italy R. Calafiori (2 Assists)
Norway M. Odegaard (2 Assists)
England E. Eze (2 Assists)
Belgium L. Trossard (2 Assists)
Best assists
Argentina J. Alvarez (5 Assists)

Arsenal and Atletico Madrid Stats in Champions League

Arsenal
Arsenal
Atletico Madrid
Atletico Madrid
100%
Wins
50%
0%
Draw
0%
0%
Losses
50%
2
Total goals per match
5.5
2
Goals scored per match
3.5
0
Goals conceded per match
2
0%
Over 2.5
100%
100%
Under 2.5
0%
0%
BTTS
100%
100%
Clean Sheet
0%

Arsenal - Atletico Madrid Key Points

  1. Arsenal are unbeaten in their last eight matches across all competitions.
  2. Arsenal have won their last 14 group-stage home games in UEFA competitions.
  3. Arsenal have kept clean sheets in four of their five home games in all competitions this season.
  4. Atletico Madrid have not won an away game in any competition this season.
  5. Atletico Madrid are winless in their last nine UCL group stage matches against English teams.
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Our Arsenal vs Atletico Madrid Prediction

It isn't often that Atletico Madrid enter matches as big underdogs, but that’s the case in this fixture, and much of the reason for that is because they have been very poor on the road this season.

Arsenal, meanwhile, have been excellent this term, perched atop the Premier League standings, and unbeaten in their last eight games. The Gunners have turned the Emirates into a fortress in Europe, and we feel they will keep their flawless record intact in this one. Our Arsenal vs Atletico Madrid prediction is Arsenal wins the match. 

Prediction :

 

Arsenal wins the match

 
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Arsenal vs Atletico Madrid - Other Interesting Predictions

Both teams to score (NO)

Odds 1.8
Arsenal have kept clean sheets in four of their five home games in all competitions this season and have not conceded a single goal in their last 11 UEFA competition group-stage matches at the Emirates.
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Arsenal vs Atletico Madrid match : Frequently asked questions

The Champions League match between Arsenal and Atletico Madrid will take place on October 21 at 20:00 BST. 

The Champions League match between Arsenal and Atletico Madrid will be played at the Emirates Stadium in London. 

The Champions League match between Arsenal and Atletico Madrid will be broadcast live on Amazon Prime in the UK.

Alternatively, you can keep up with all the action using our Champions League livescore tool.

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Arsenal vs Atletico Madrid Prediction
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