South America - Copa Libertadores
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by Ita Emmanuel | in Copa Libertadores Predictions
This Copa Libertadores quarter-final second leg will see Sao Paulo play host to LDU Quito on Thursday at Estadio Do MorumBIS. Can the Sovereign overturn their first-leg defeat in Ecuador against the Whites to book their place in the semi-finals? Follow our prediction for the match below.
Sao Paulo are on the verge of crashing out of the 2025 Copa Libertadores following a 2-0 defeat in Ecuador in the first leg of this tie. Goals from Bryan Josias Ramirez Leon and Michael Estrada condemned the Brazilian giants to their first defeat in the competition this season.
They also lost 1-0 to domestic rivals Santos in the Brazil Serie A in their last outing on Monday, marking their third defeat in four games. However, Hernán Crespo’s men have been in terrific form at home. They are unbeaten in their last seven home fixtures, winning six and drawing one in regulation time.
LDU Quito couldn't sustain their recent winning momentum in their last outing. The Whites suffered a 4-2 home defeat to U. Catolica in their domestic league fixture at the weekend. They have also lost three of their last four away matches and will face a big challenge preserving their two-goal lead against Sao Paulo to secure this year’s Copa Libertadores semi-final ticket.
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The Best Betting Odds for SAO Paulo v LDU Quito Match
Bookmaker | 1 | X | 2 | Bonus up to |
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1.38 | 4.2 | 10 |
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1.36 | 4.33 | 8 |
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1.4 | 4.2 | 8.5 |
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1.4 | 4.5 | 9 |
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1.33 | 3.83 | 9.2 |
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What is the prediction for the football match between SAO Paulo and LDU Quito?
Our prediction for the SAO Paulo vs LDU Quito match is: one of the teams to keep a clean sheet.
Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 25/09/2025 between SAO Paulo and LDU Quito in Copa Libertadores :
- The Sportytrader ⭐ algorithm estimates a probability of 59.48% for a win of SAO Paulo against LDU Quito with odds of 1.41 at Tonybet.
- The probability according to Sportytrader ⭐ for a draw between SAO Paulo vs LDU Quito is 15.9% with odds of 4.5 at Unibet.
- Our prediction model gives a 24.61% chance ⭐ for a win of LDU Quito vs SAO Paulo with odds of 10 at Bet365.
SAO Paulo vs LDU Quito Form
SAO Paulo and LDU Quito Last Matches

2/6 (33%)
1/6 (17%)
3/6 (50%)
Average stats (Last 6 matchs)
21 Sep 2025 - Brasileirão Serie A
18 Sep 2025 - Copa Libertadores
14 Sep 2025 - Brasileirão Serie A
30 Aug 2025 - Brasileirão Serie A
24 Aug 2025 - Brasileirão Serie A
19 Aug 2025 - Copa Libertadores
5/6 (83%)
1/6 (17%)
0/6 (0%)
Average stats (Last 6 matchs)
14 Sep 2025 - Brasileirão Serie A
24 Aug 2025 - Brasileirão Serie A
19 Aug 2025 - Copa Libertadores
9 Aug 2025 - Brasileirão Serie A
31 Jul 2025 - Copa do Brasil
27 Jul 2025 - Brasileirão Serie A
0/6 (0%)
2/6 (33%)
4/6 (67%)
Average stats (Last 6 matchs)
21 Sep 2025 - Brasileirão Serie A
18 Sep 2025 - Copa Libertadores
30 Aug 2025 - Brasileirão Serie A
16 Aug 2025 - Brasileirão Serie A
12 Aug 2025 - Copa Libertadores
6 Aug 2025 - Copa do Brasil

3/6 (50%)
1/6 (17%)
2/6 (33%)
Average stats (Last 6 matchs)
21 Sep 2025 - Serie A
18 Sep 2025 - Copa Libertadores
12 Sep 2025 - Serie A
30 Aug 2025 - Serie A
24 Aug 2025 - Serie A
21 Aug 2025 - Copa Libertadores
3/6 (50%)
2/6 (33%)
1/6 (17%)
Average stats (Last 6 matchs)
21 Sep 2025 - Serie A
18 Sep 2025 - Copa Libertadores
30 Aug 2025 - Serie A
21 Aug 2025 - Copa Libertadores
17 Aug 2025 - Serie A
3 Aug 2025 - Serie A
2/6 (33%)
1/6 (17%)
3/6 (50%)
Average stats (Last 6 matchs)
12 Sep 2025 - Serie A
24 Aug 2025 - Serie A
14 Aug 2025 - Copa Libertadores
9 Aug 2025 - Serie A
24 Jul 2025 - Serie A
16 Jul 2025 - Copa Ecuador
SAO Paulo vs LDU Quito Stats: Head to Head (H2H)
40 %
0 %
60 %
Average stats (last H2H results)
18 Sep 2025 - Copa Libertadores
31 Aug 2023 - Copa Sudamericana
24 Aug 2023 - Copa Sudamericana
22 Sep 2020 - Copa Libertadores
11 Mar 2020 - Copa Libertadores
Most goals and assists








SAO Paulo and LDU Quito Stats in Copa Libertadores


SAO Paulo - LDU Quito Key Points
- Sao Paulo's last five matches have ended with one of the teams keeping a clean sheet.
- One of the teams has kept a clean sheet in three of Sao Paulo's last four home fixtures.
- One of the teams have kept a clean sheet in four of LDU Quito's last six matches.
- Each of LDU Quito's last five away matches has ended with at least one team keeping a clean sheet.
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Our SAO Paulo vs LDU Quito Prediction
Despite their recent poor overall form, Sao Paulo remain bookmakers’ favourites to win this match. The Tricolors have their home advantage to count on, including their terrific recent ride at Estadio Do MorumBIS – a stark contrast to LDU Quito’s recent struggles on the road.
Meanwhile, the two teams’ recent fixtures have been mostly low-scoring affairs, with at least one side keeping a clean sheet. Given this trend, we are tipping one of the teams to emerge with a clean sheet. Our Sao Paulo vs LDU Quito prediction is one of the teams to keep a clean sheet.
Use £/€50 free bets for the SAO Paulo vs. LDU Quito game!
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Try your luck on this year's Copa Libertadores! You need to make your qualifying bet of €/£10 within 30 days of opening an account and this can be on any sport with at least one selection priced at 1.2 (1/5) or bigger.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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