Southampton vs Arsenal Prediction & Betting Tips - FA Cup

England - FA Cup

Southampton
04/04/2026 15:00
Arsenal

Prediction :

 

BTTS

 
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 by Kennedy Kechula | in FA Cup Predictions

Arsenal head to St. Mary’s Stadium upon return from the international break, where they will face Southampton in the FA Cup. This will be in the quarter-finals, Southampton targeting a 15th undefeated outing and Arsenal a rise after their League Cup final disappointment. Read on to find our prediction for the match.

For the Gunners, the return to club football heralds a very busy period. They are scheduled to face Sporting Lisbon twice in the Champions League in the coming weeks. Meanwhile, it is crunch time in the Premier League as well, with a pivotal game against Manchester City on the horizon.

Busy times are not only unique for Arsenal; Southampton also have a lot of balancing acts to focus on. They are chasing a straight return to the Premier League and are currently doing well on that front. Getting that and advancing deeper in the FA Cup will qualify this as a successful season. All that needs boots on the ground for Eckert Tonda and his charges.

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Southampton v Arsenal Best Betting Odds

Bookmaker 1 X 2 Bonus up to
Stake
7 5 1.39
Melbet
7.2 5.1 1.39
Betwinner
7.7 5.05 1.38
Bet365
6.25 5 1.39
Roobet
7.2 5 1.4
Check all Southampton vs Arsenal odds

What is the prediction for the football match between Southampton and Arsenal?

Our prediction for the Southampton vs Arsenal match is: BTTS.

Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 04/04/2026 between Southampton and Arsenal in FA Cup :

  • The Sportytrader ⭐ algorithm estimates a probability of 33.95% for a win of Southampton against Arsenal with odds of 8 at LSbet.
  • The probability according to Sportytrader ⭐ for a draw between Southampton vs Arsenal is 29.02% with odds of 5.2 at Tonybet.
  • Our prediction model gives a 37.03% chance ⭐ for a win of Arsenal vs Southampton with odds of 1.43 at 888Starz.

Southampton - Arsenal Prediction and Best Odds:

Southampton Arsenal Prediction Probability Odds
Arsenal wins 37.03% 1.43 at 888Starz
Under 2.5 55.2% 2.42 at Shangrila
Both Team To Score 57.92%
Half-time: Draw / Full-time: Arsenal 15.17% 4.33 at Bet365

Southampton vs Arsenal Form

Southampton and Arsenal Last Matches

Southampton
Southampton Last matches
W W D W W W
Wins

5/6 (83%)

Draw

1/6 (17%)

Losses

0/6 (0%)

Average stats (Last 6 matchs)

2.17 Total goals
50% BTTS
1.67 Goals scored
0.5 Goals conceded
33% Over 2.5
67% Under 2.5

21 Mar 2026 - Championship

Southampton
2 :  0
Oxford United

18 Mar 2026 - Championship

Southampton
1 :  0
Norwich

14 Mar 2026 - Championship

Coventry City
1 :  2
Southampton

11 Mar 2026 - Championship

West Brom
1 :  1
Southampton

8 Mar 2026 - FA Cup

Fulham
0 :  1
Southampton

28 Feb 2026 - Championship

Sheffield Wednesday
1 :  3
Southampton
W W D W W W
Wins

5/6 (83%)

Draw

1/6 (17%)

Losses

0/6 (0%)

Average stats (Last 6 matchs)

2.33 Total goals
33% BTTS
2 Goals scored
0.33 Goals conceded
33% Over 2.5
67% Under 2.5

21 Mar 2026 - Championship

Southampton
2 :  0
Oxford United

18 Mar 2026 - Championship

Southampton
1 :  0
Norwich

24 Feb 2026 - Championship

Southampton
5 :  0
QPR

21 Feb 2026 - Championship

Southampton
1 :  1
Charlton Athletic

14 Feb 2026 - FA Cup

Southampton
2 :  1
Leicester

7 Feb 2026 - Championship

Southampton
1 :  0
Watford
W W W W D W
Wins

5/6 (83%)

Draw

1/6 (17%)

Losses

0/6 (0%)

Average stats (Last 6 matchs)

3.17 Total goals
67% BTTS
2.17 Goals scored
1 Goals conceded
50% Over 2.5
50% Under 2.5

14 Mar 2026 - Championship

Coventry City
1 :  2
Southampton

11 Mar 2026 - Championship

West Brom
1 :  1
Southampton

8 Mar 2026 - FA Cup

Fulham
0 :  1
Southampton

28 Feb 2026 - Championship

Sheffield Wednesday
1 :  3
Southampton

10 Feb 2026 - Championship

Leicester
3 :  4
Southampton

31 Jan 2026 - Championship

Stoke
0 :  2
Southampton
Arsenal
Arsenal Last matches
W W D W W L
Wins

4/6 (67%)

Draw

1/6 (17%)

Losses

1/6 (17%)

Average stats (Last 6 matchs)

2 Total goals
33% BTTS
1.33 Goals scored
0.67 Goals conceded
17% Over 2.5
83% Under 2.5

22 Mar 2026 - Carabao Cup

Arsenal
0 :  2
Manchester City

17 Mar 2026 - Champions League

Arsenal
2 :  0
Bayer Leverkusen

14 Mar 2026 - Premier League

Arsenal
2 :  0
Everton

11 Mar 2026 - Champions League

Bayer Leverkusen
1 :  1
Arsenal

7 Mar 2026 - FA Cup

Mansfield Town
1 :  2
Arsenal

4 Mar 2026 - Premier League

Brighton
0 :  1
Arsenal
W W W W W L
Wins

5/6 (83%)

Draw

0/6 (0%)

Losses

1/6 (17%)

Average stats (Last 6 matchs)

2.67 Total goals
17% BTTS
2.17 Goals scored
0.5 Goals conceded
50% Over 2.5
50% Under 2.5

22 Mar 2026 - Carabao Cup

Arsenal
0 :  2
Manchester City

17 Mar 2026 - Champions League

Arsenal
2 :  0
Bayer Leverkusen

14 Mar 2026 - Premier League

Arsenal
2 :  0
Everton

1 Mar 2026 - Premier League

Arsenal
2 :  1
Chelsea

15 Feb 2026 - FA Cup

Arsenal
4 :  0
Wigan

7 Feb 2026 - Premier League

Arsenal
3 :  0
Sunderland
D D W W W D
Wins

3/6 (50%)

Draw

3/6 (50%)

Losses

0/6 (0%)

Average stats (Last 6 matchs)

2.83 Total goals
83% BTTS
1.83 Goals scored
1 Goals conceded
50% Over 2.5
50% Under 2.5

11 Mar 2026 - Champions League

Bayer Leverkusen
1 :  1
Arsenal

7 Mar 2026 - FA Cup

Mansfield Town
1 :  2
Arsenal

4 Mar 2026 - Premier League

Brighton
0 :  1
Arsenal

22 Feb 2026 - Premier League

Tottenham
1 :  4
Arsenal

18 Feb 2026 - Premier League

Wolves
2 :  2
Arsenal

12 Feb 2026 - Premier League

Brentford
1 :  1
Arsenal

Southampton vs Arsenal Stats: Head to Head (H2H)

Southampton

17 %

Draw

33 %

Arsenal

50 %

Average stats (last H2H results)

3.17
Total goals
66.67%
BTTS
1.17
Goals scored
2
Goals conceded
66.67%
Over 2.5
33.33%
Under 2.5

25 May 2025 - Premier League

Southampton
1 :  2
Arsenal

5 Oct 2024 - Premier League

Arsenal
3 :  1
Southampton

21 Apr 2023 - Premier League

Arsenal
3 :  3
Southampton

23 Oct 2022 - Premier League

Southampton
1 :  1
Arsenal

16 Apr 2022 - Premier League

Southampton
1 :  0
Arsenal

11 Dec 2021 - Premier League

Arsenal
3 :  0
Southampton

Southampton - Arsenal: Form Analysis

Southampton have been doing well in recent months and head into this game as one of the sides likely to be in the Premier League next season. At the moment, they will put on hold their impressive performances in the Championship for an equally important assignment.

The Saints are set to host the most successful side in FA Cup history, and they look to cause a major upset. While they come here as underdogs, the hosts will not be short of confidence. They are unbeaten in their last 14 games across all competitions, winning 11. The Saints saw off Doncaster, Leicester City, and Premier League side Fulham to book this slot.

Arsenal beat Southampton in the teams’ last two meetings.

Arsenal have had the whole of two weeks to reflect on their fourth defeat of the season, which came as a crushing blow. The Gunners were uncharacteristically timid as they suffered a 2-0 loss to Manchester City in the League Cup final at Wembley.

That was their last act before the international break, and Mikel Arteta will hope to welcome back a more positive and competitive unit. Their defeat to City ended a 14-game unbeaten stretch for the Gunners, who will be more than willing to restart it again. In the last round, Arsenal made hard work of their 2-1 win away at Mansfield Town and will be expected to do better at another hostile venue.

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Southampton vs Arsenal Prediction

Southampton against Arsenal Lineups: Starting 11

Southampton

Formation : 4 - 2 - 3 - 1

41
D. Peretz
14
J. Bree
6
T. Harwood-Bellis
15
N. Wood
3
R. Manning
48
C. Bragg
20
C. Jander
18
T. Fellows
10
F. Azaz
13
L. Scienza
11
R. Stewart
9
G. Jesus
11
G. Martinelli
29
K. Havertz
56
M. Dowman
16
C. Norgaard
8
M. Odegaard
49
M. Lewis-Skelly
6
G. Magalhaes
3
C. Mosquera
4
B. White
13
K. Arrizabalaga

Formation : 4 - 2 - 3 - 1

Arsenal

Substitutes

Southampton
Southampton
Goalkeeper

G. Long

Defender

J. Quarshie

R. Manning 90'

Midfielder

O. Romeu

S. Charles

C. Bragg 76'

Forward

N. Oyekunle

C. Archer

S. Edozie

L. Scienza 71'

J. Robinson

C. Larin

R. Stewart 70'

Arsenal
Arsenal
Goalkeeper

D. Raya

Defender

W. Saliba

G. Magalhaes 72'

M. Salmon

R. Calafiori

M. Lewis-Skelly 60'

Midfielder

M. Zubimendi

K. Havertz 79'

A. Harriman-Annous

Forward

N. Madueke

M. Odegaard 61'

C. O'Neill

V. Gyokeres

G. Jesus 60'

Missing players

Southampton
Southampton
Defender

M. Roerslev

Welington

Arsenal
Arsenal
Defender

J. Timber

P. Hincapie

Midfielder

M. Merino

E. Eze

Forward

L. Trossard

Southampton & Arsenal Squad Analysis

Southampton’s plans for this game will be greatly affected by the absence of key players. On account of suspension and injuries, Eckert Tonda is set to miss at least four players. Flynn Downes and Matsuki Kuryu are both suspended after receiving second bookings in the win against Fulham.

Their absence will cost the Saints creativity in the final third. It doesn’t get better for the hosts with news that skipper Jack Stephens is out after sustaining an injury in training. He joins a long list of team mates in the infirmary, including Leo Scienza, Alex McCarthy, Jay Robinson, and Mads Roerslev.

Arsenal forward Viktor Gyokeres scored four times during the international break.

Arsenal have none suspended. The Gunners saw 18 of their players called up for international duty. Incredibly, at least 10 had to pull out of their respective national teams with injury concerns. It remains unclear which players will feature in this encounter, but with a head injury, Noni Madueke is definitely out.

Skipper Martin Odegaard has been battling a knee issue, and we don’t foresee his return here. One other definite absentee is Mikel Merino, who is nursing a foot injury.

Southampton - Arsenal Key Points

  1. Southampton scored in each of their last 16 matches.
  2. Arsenal failed to score once in their last 17 matches.
  3. In the last four meetings between these sides, both scored.
  4. Away from home, Arsenal managed only three clean sheets in 10.
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Our Southampton vs Arsenal Prediction

While Arsenal boasts of the best defence in the Premier League, they haven't been keeping many clean sheets of late. The Gunners conceded in seven of their last 10 matches, and there is a possibility that this trend will continue here.

That is strengthened by Southampton’s own attacking prowess, which should test the Gunners, backed by the home crowd. The Saints will, however, have to deal with Arsenal’s top brand of attacking players as well. As such, our prediction for Southampton v Arsenal is BTTS.

Prediction :

 

BTTS

 
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Southampton vs Arsenal Alternative Predictions

Arsenal wins

Odds 1.25

All season, Arsenal have responded well to defeat. They have won after each of their previous three losses and will be favorites for the same here. They also come here with a good run against Southampton, having won their last two meetings. Our second prediction for this game is that Arsenal wins.

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Last Minute: Pre-match odds analysis Southampton Arsenal

Southampton vs Arsenal Opening odds Pre-match odds Odds Movements
Southampton wins 13 8 -38.5%
Draw 6.75 5.2 -23.0%
Arsenal wins 1.22 1.43 +17.2%
Latest odds movements:

After kick-off, the latest odds movements show that:

  • Arsenal is most likely to win
  • The odds for this bet have increased by 17.2% since opening
  • The probability of this result was 82.0% and is now 69.9% (-12.0%)

Southampton vs Arsenal - FAQs

The Southampton v Arsenal match will be played at St. Mary’s Stadium.

The Southampton v Arsenal match will be played on Saturday, April 4.

All tips are fully researched and given in good faith, but profits cannot be guaranteed.