Southampton vs Arsenal Prediction & Betting Tips - FA Cup
England - FA Cup
New customers only | Commercial content | 18+ age limit | T&Cs apply
by Kennedy Kechula | in FA Cup Predictions
Arsenal head to St. Mary’s Stadium upon return from the international break, where they will face Southampton in the FA Cup. This will be in the quarter-finals, Southampton targeting a 15th undefeated outing and Arsenal a rise after their League Cup final disappointment. Read on to find our prediction for the match.
For the Gunners, the return to club football heralds a very busy period. They are scheduled to face Sporting Lisbon twice in the Champions League in the coming weeks. Meanwhile, it is crunch time in the Premier League as well, with a pivotal game against Manchester City on the horizon.
Busy times are not only unique for Arsenal; Southampton also have a lot of balancing acts to focus on. They are chasing a straight return to the Premier League and are currently doing well on that front. Getting that and advancing deeper in the FA Cup will qualify this as a successful season. All that needs boots on the ground for Eckert Tonda and his charges.
Limited Offer. Currently at Stake
Southampton v Arsenal Best Betting Odds
| Bookmaker | 1 | X | 2 | Bonus up to |
|---|---|---|---|---|
|
|
7 | 5 | 1.39 |
|
|
|
7.2 | 5.1 | 1.39 |
|
|
|
7.7 | 5.05 | 1.38 |
|
|
|
6.25 | 5 | 1.39 |
|
|
|
7.2 | 5 | 1.4 |
|
What is the prediction for the football match between Southampton and Arsenal?
Our prediction for the Southampton vs Arsenal match is: BTTS.
Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 04/04/2026 between Southampton and Arsenal in FA Cup :
- The Sportytrader ⭐ algorithm estimates a probability of 33.95% for a win of Southampton against Arsenal with odds of 8 at LSbet.
- The probability according to Sportytrader ⭐ for a draw between Southampton vs Arsenal is 29.02% with odds of 5.2 at Tonybet.
- Our prediction model gives a 37.03% chance ⭐ for a win of Arsenal vs Southampton with odds of 1.43 at 888Starz.
Southampton - Arsenal Prediction and Best Odds:
| Southampton Arsenal Prediction | Probability | Odds |
|---|---|---|
| Arsenal wins | 37.03% | 1.43 at 888Starz |
| Under 2.5 | 55.2% | 2.42 at Shangrila |
| Both Team To Score | 57.92% | |
| Half-time: Draw / Full-time: Arsenal | 15.17% | 4.33 at Bet365 |
Southampton vs Arsenal Form
Southampton and Arsenal Last Matches
5/6 (83%)
1/6 (17%)
0/6 (0%)
Average stats (Last 6 matchs)
21 Mar 2026 - Championship
18 Mar 2026 - Championship
14 Mar 2026 - Championship
11 Mar 2026 - Championship
8 Mar 2026 - FA Cup
28 Feb 2026 - Championship
5/6 (83%)
1/6 (17%)
0/6 (0%)
Average stats (Last 6 matchs)
21 Mar 2026 - Championship
18 Mar 2026 - Championship
24 Feb 2026 - Championship
21 Feb 2026 - Championship
14 Feb 2026 - FA Cup
7 Feb 2026 - Championship
5/6 (83%)
1/6 (17%)
0/6 (0%)
Average stats (Last 6 matchs)
14 Mar 2026 - Championship
11 Mar 2026 - Championship
8 Mar 2026 - FA Cup
28 Feb 2026 - Championship
10 Feb 2026 - Championship
31 Jan 2026 - Championship
4/6 (67%)
1/6 (17%)
1/6 (17%)
Average stats (Last 6 matchs)
22 Mar 2026 - Carabao Cup
17 Mar 2026 - Champions League
14 Mar 2026 - Premier League
11 Mar 2026 - Champions League
7 Mar 2026 - FA Cup
4 Mar 2026 - Premier League
5/6 (83%)
0/6 (0%)
1/6 (17%)
Average stats (Last 6 matchs)
22 Mar 2026 - Carabao Cup
17 Mar 2026 - Champions League
14 Mar 2026 - Premier League
1 Mar 2026 - Premier League
15 Feb 2026 - FA Cup
7 Feb 2026 - Premier League
3/6 (50%)
3/6 (50%)
0/6 (0%)
Average stats (Last 6 matchs)
11 Mar 2026 - Champions League
7 Mar 2026 - FA Cup
4 Mar 2026 - Premier League
22 Feb 2026 - Premier League
18 Feb 2026 - Premier League
12 Feb 2026 - Premier League
Southampton vs Arsenal Stats: Head to Head (H2H)
17 %
33 %
50 %
Average stats (last H2H results)
25 May 2025 - Premier League
5 Oct 2024 - Premier League
21 Apr 2023 - Premier League
23 Oct 2022 - Premier League
16 Apr 2022 - Premier League
11 Dec 2021 - Premier League
Southampton - Arsenal: Form Analysis
Southampton have been doing well in recent months and head into this game as one of the sides likely to be in the Premier League next season. At the moment, they will put on hold their impressive performances in the Championship for an equally important assignment.
The Saints are set to host the most successful side in FA Cup history, and they look to cause a major upset. While they come here as underdogs, the hosts will not be short of confidence. They are unbeaten in their last 14 games across all competitions, winning 11. The Saints saw off Doncaster, Leicester City, and Premier League side Fulham to book this slot.
Arsenal beat Southampton in the teams’ last two meetings.
Arsenal have had the whole of two weeks to reflect on their fourth defeat of the season, which came as a crushing blow. The Gunners were uncharacteristically timid as they suffered a 2-0 loss to Manchester City in the League Cup final at Wembley.
That was their last act before the international break, and Mikel Arteta will hope to welcome back a more positive and competitive unit. Their defeat to City ended a 14-game unbeaten stretch for the Gunners, who will be more than willing to restart it again. In the last round, Arsenal made hard work of their 2-1 win away at Mansfield Town and will be expected to do better at another hostile venue.
Limited Offer. Currently at Stake
Southampton against Arsenal Lineups: Starting 11
Formation : 4 - 2 - 3 - 1
Formation : 4 - 2 - 3 - 1
Substitutes
G. Long
DefenderJ. Quarshie
O. Romeu
S. Charles
N. Oyekunle
C. Archer
S. Edozie
J. Robinson
C. Larin
D. Raya
DefenderW. Saliba
M. Salmon
R. Calafiori
M. Zubimendi
A. Harriman-Annous
ForwardN. Madueke
C. O'Neill
V. Gyokeres
Missing players
M. Roerslev
Welington
J. Timber
P. Hincapie
MidfielderM. Merino
E. Eze
ForwardL. Trossard
Southampton & Arsenal Squad Analysis
Southampton’s plans for this game will be greatly affected by the absence of key players. On account of suspension and injuries, Eckert Tonda is set to miss at least four players. Flynn Downes and Matsuki Kuryu are both suspended after receiving second bookings in the win against Fulham.
Their absence will cost the Saints creativity in the final third. It doesn’t get better for the hosts with news that skipper Jack Stephens is out after sustaining an injury in training. He joins a long list of team mates in the infirmary, including Leo Scienza, Alex McCarthy, Jay Robinson, and Mads Roerslev.
Arsenal forward Viktor Gyokeres scored four times during the international break.
Arsenal have none suspended. The Gunners saw 18 of their players called up for international duty. Incredibly, at least 10 had to pull out of their respective national teams with injury concerns. It remains unclear which players will feature in this encounter, but with a head injury, Noni Madueke is definitely out.
Skipper Martin Odegaard has been battling a knee issue, and we don’t foresee his return here. One other definite absentee is Mikel Merino, who is nursing a foot injury.
Southampton - Arsenal Key Points
- Southampton scored in each of their last 16 matches.
- Arsenal failed to score once in their last 17 matches.
- In the last four meetings between these sides, both scored.
- Away from home, Arsenal managed only three clean sheets in 10.
Limited Offer. Currently at Stake
Our Southampton vs Arsenal Prediction
While Arsenal boasts of the best defence in the Premier League, they haven't been keeping many clean sheets of late. The Gunners conceded in seven of their last 10 matches, and there is a possibility that this trend will continue here.
That is strengthened by Southampton’s own attacking prowess, which should test the Gunners, backed by the home crowd. The Saints will, however, have to deal with Arsenal’s top brand of attacking players as well. As such, our prediction for Southampton v Arsenal is BTTS.
Southampton vs Arsenal Alternative Predictions
Arsenal wins
All season, Arsenal have responded well to defeat. They have won after each of their previous three losses and will be favorites for the same here. They also come here with a good run against Southampton, having won their last two meetings. Our second prediction for this game is that Arsenal wins.
Last Minute: Pre-match odds analysis Southampton Arsenal
| Southampton vs Arsenal | Opening odds | Pre-match odds | Odds Movements |
|---|---|---|---|
| Southampton wins | 13 | 8 | -38.5% |
| Draw | 6.75 | 5.2 | -23.0% |
| Arsenal wins | 1.22 | 1.43 | +17.2% |
After kick-off, the latest odds movements show that:
- Arsenal is most likely to win
- The odds for this bet have increased by 17.2% since opening
- The probability of this result was 82.0% and is now 69.9% (-12.0%)
Southampton vs Arsenal - FAQs
The Southampton v Arsenal match will be played at St. Mary’s Stadium.
The Southampton v Arsenal match will be played on Saturday, April 4.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.