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Manchester City vs Bayer Leverkusen Prediction & Betting Tips - Champions League

Europe - Champions League

Manchester City
25/11/2025 15:00
Bayer Leverkusen

Prediction :

 

Half-time/Full-time: Manchester City/Manchester City

 
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 by Steve Ashfield in Champions League Predictions

After another loss in the English Premier League, Manchester City will hope to get a win in Europe. The Citizens are fourth in the Champions League and on Tuesday are home to Bayer Leverkusen who are 21st in the table. Read our match prediction below.

City were beaten at Newcastle on Saturday again damaging their chances of regaining the English Premier League title. Their Champions League campaign has been going much better though and they are unbeaten after their first four matches of the league phase. After this match they have two away games, beginning with a trip to Real Madrid. A home win here is very much needed to stay in the top eight.

Bayer Leverkusen are four points adrift of the automatic qualification places for the last 16. Only one of their four games has been won in the league phase. They are second in the German Bundesliga, eight points behind Bayern Munich. Two of their final three games will be at home.

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The Best Betting Odds for Manchester City v Bayer Leverkusen Match

Bookmaker 1 X 2 Bonus up to
Bet365
1.22 6.25 11
Betfred
1.2 6.5 11
William Hill
1.25 6 11
Betway
1.22 6.5 11
Unibet
1.21 7 12
Check all Manchester City vs Bayer Leverkusen odds

What is the prediction for the football match between Manchester City and Bayer Leverkusen?

Our prediction for the Manchester City vs Bayer Leverkusen match is: Manchester City wins and leads at half and full time.

Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 25/11/2025 between Manchester City and Bayer Leverkusen in Champions League :

  • The Sportytrader ⭐ algorithm estimates a probability of 59.97% for a win of Manchester City against Bayer Leverkusen with odds of 1.27 at 888Starz.
  • The probability according to Sportytrader ⭐ for a draw between Manchester City vs Bayer Leverkusen is 3.15% with odds of 7 at Unibet.
  • Our prediction model gives a 36.88% chance ⭐ for a win of Bayer Leverkusen vs Manchester City with odds of 12.4 at 888Starz.

Manchester City vs Bayer Leverkusen Form

Manchester City and Bayer Leverkusen's standings in the Champions League

Teams Pts P W D L GD
4
Manchester City
Manchester City
10 4 3 1 0 7
21
Bayer Leverkusen
Bayer Leverkusen
5 4 1 2 1 -4

Manchester City and Bayer Leverkusen Last Matches

Manchester City
Manchester City Last matches
L W W W W L
Wins

4/6 (67%)

Draw

0/6 (0%)

Losses

2/6 (33%)

Average stats (Last 6 matchs)

3.33 Total goals
67% BTTS
2.33 Goals scored
1 Goals conceded
83% Over 2.5
17% Under 2.5

22 Nov 2025 - Premier League

Newcastle
2 :  1
Manchester City

9 Nov 2025 - Premier League

Manchester City
3 :  0
Liverpool

5 Nov 2025 - Champions League

Manchester City
4 :  1
Borussia Dortmund

2 Nov 2025 - Premier League

Manchester City
3 :  1
Bournemouth

29 Oct 2025 - Carabao Cup

Swansea
1 :  3
Manchester City

26 Oct 2025 - Premier League

Aston Villa
1 :  0
Manchester City
W W W W W W
Wins

6/6 (100%)

Draw

0/6 (0%)

Losses

0/6 (0%)

Average stats (Last 6 matchs)

3.67 Total goals
50% BTTS
3.17 Goals scored
0.5 Goals conceded
67% Over 2.5
33% Under 2.5

9 Nov 2025 - Premier League

Manchester City
3 :  0
Liverpool

5 Nov 2025 - Champions League

Manchester City
4 :  1
Borussia Dortmund

2 Nov 2025 - Premier League

Manchester City
3 :  1
Bournemouth

18 Oct 2025 - Premier League

Manchester City
2 :  0
Everton

27 Sept 2025 - Premier League

Manchester City
5 :  1
Burnley

18 Sept 2025 - Champions League

Manchester City
2 :  0
Napoli
D W W L W L
Wins

3/6 (50%)

Draw

1/6 (17%)

Losses

2/6 (33%)

Average stats (Last 6 matchs)

2.5 Total goals
50% BTTS
1.5 Goals scored
1 Goals conceded
50% Over 2.5
50% Under 2.5

22 Nov 2025 - Premier League

Newcastle
2 :  1
Manchester City

29 Oct 2025 - Carabao Cup

Swansea
1 :  3
Manchester City

26 Oct 2025 - Premier League

Aston Villa
1 :  0
Manchester City

21 Oct 2025 - Champions League

Villarreal
0 :  2
Manchester City

5 Oct 2025 - Premier League

Brentford
0 :  1
Manchester City

1 Oct 2025 - Champions League

Monaco
2 :  2
Manchester City
Bayer Leverkusen
Bayer Leverkusen Last matches
W W L W W W
Wins

5/6 (83%)

Draw

0/6 (0%)

Losses

1/6 (17%)

Average stats (Last 6 matchs)

3.67 Total goals
33% BTTS
2.67 Goals scored
1 Goals conceded
67% Over 2.5
33% Under 2.5

22 Nov 2025 - Bundesliga

Wolfsburg
1 :  3
Bayer Leverkusen

8 Nov 2025 - Bundesliga

Bayer Leverkusen
6 :  0
Heidenheim

5 Nov 2025 - Champions League

Benfica Lisbon
0 :  1
Bayer Leverkusen

1 Nov 2025 - Bundesliga

Bayern Munich
3 :  0
Bayer Leverkusen

29 Oct 2025 - DFB Pokal

Paderborn
2 :  4
Bayer Leverkusen

26 Oct 2025 - Bundesliga

Bayer Leverkusen
2 :  0
Freiburg
D D W L W W
Wins

3/6 (50%)

Draw

2/6 (33%)

Losses

1/6 (17%)

Average stats (Last 6 matchs)

3.83 Total goals
50% BTTS
2.33 Goals scored
1.5 Goals conceded
33% Over 2.5
67% Under 2.5

8 Nov 2025 - Bundesliga

Bayer Leverkusen
6 :  0
Heidenheim

26 Oct 2025 - Bundesliga

Bayer Leverkusen
2 :  0
Freiburg

21 Oct 2025 - Champions League

Bayer Leverkusen
2 :  7
PSG

4 Oct 2025 - Bundesliga

Bayer Leverkusen
2 :  0
Union Berlin

1 Oct 2025 - Champions League

Bayer Leverkusen
1 :  1
PSV Eindhoven

21 Sept 2025 - Bundesliga

Bayer Leverkusen
1 :  1
Mönchengladbach
W W W L W W
Wins

5/6 (83%)

Draw

0/6 (0%)

Losses

1/6 (17%)

Average stats (Last 6 matchs)

4 Total goals
67% BTTS
2.33 Goals scored
1.67 Goals conceded
83% Over 2.5
17% Under 2.5

22 Nov 2025 - Bundesliga

Wolfsburg
1 :  3
Bayer Leverkusen

5 Nov 2025 - Champions League

Benfica Lisbon
0 :  1
Bayer Leverkusen

1 Nov 2025 - Bundesliga

Bayern Munich
3 :  0
Bayer Leverkusen

29 Oct 2025 - DFB Pokal

Paderborn
2 :  4
Bayer Leverkusen

18 Oct 2025 - Bundesliga

1 Fsv Mainz 05
3 :  4
Bayer Leverkusen

27 Sept 2025 - Bundesliga

St. Pauli
1 :  2
Bayer Leverkusen
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Manchester City - Bayer Leverkusen: Form Analysis

Manchester City are one of five clubs yet to lose a match in the league phase. Last season saw them lose in the last 16 of the Champions League and the Blues will certainly want to progress further this term.

City began their Champions League campaign with a 2-0 home win over Napoli. That was followed by a 2-2 draw in Monaco but they led twice and conceded a 90th minute equalizer. They got back into winning ways with a 2-0 win at Villarreal.

It's a tight battle for the automatic qualification places.

A 4-1 home win over Borussia Dortmund was another excellent result for City. They are only two points behind leaders Bayern Munich but just a point above ninth place, so can't afford any slip-ups like the 2-1 loss at Newcastle on Saturday.

Bayer Leverkusen have earned five points from their first four games in the league phase. They currently sit in the unseeded play-off positions but are only two points behind the seeded positions. 

The German Bundesliga side have one victory in the league phase so far. That sole success came in their most recent game, winning 1-0 at Benfica. It was a much-needed victory after the heavy 7-2 home loss to PSG that had followed two opening draws.

At the weekend, they won 3-1 at Wolfsburg, their third successive win since losing 3-0 away to Bayern Munich.

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Manchester City vs Bayer Leverkusen last Lineups

Manchester City

Formation : 4 - 3 - 3

25
G. Donnarumma
27
M. Nunes
3
R. Dias
24
J. Gvardiol
33
N. O'Reilly
20
B. Silva
14
N. Gonzalez
47
P. Foden
10
R. Cherki
9
E. Haaland
11
J. Doku
14
P. Schick
10
M. Tillman
7
J. Hofmann
20
A. Grimaldo
24
A. Garcia
30
I. Maza
19
E. Poku
12
E. Tapsoba
5
L. Bade
8
R. Andrich
1
M. Flekken

Formation : 3 - 4 - 2 - 1

Bayer Leverkusen

Missing players

Manchester City
Manchester City
Midfielder

M. Kovacic

Rodri

Bayer Leverkusen
Bayer Leverkusen
Defender

L. Vazquez

Midfielder

E. Palacios

A. Tape

E. Fernandez

Manchester City & Bayer Leverkusen Squad Analysis

The second half of the league phase gets underway on Tuesday. Manchester City look to be in a strong position but there is still plenty of work to do if they want to finish in the top eight. Just one point separates them from ninth-placed Galatasaray.

City lost at the weekend but didn't pick up any new injuries. Rodri remains doubtful for this game which is a blow in midfield. How will Guardiola react to the Newcastle loss? Some changes to their starting line-up are likely and they will hope Haaland rediscovers his scoring boots.

Injury and suspension problems for Bayer.

Bayer Leverkusen are only in the unseeded play-off positions. They will again be without midfielder Robert Andrich who is suspended. He was sent off in Leverkusen's 7-2 home loss to PSG. Leverkusen are short of midfielders and that bodes problems for them in this game.

Also suspended is defender Edmond Tapsoba. His absence should mean that England international  Jarrell Quanash should start for the German Bundesliga side. Another problem is that Ibrahim Maza is doubtful after not coming out for the second half at Wolfsburg.

Most goals and assists

CD Huachipato Manchester City
CD Huachipato Bayer Leverkusen
Top Goalscorer
Norway E. Haaland (19 Goals)
Top Goalscorer
Czech Republic P. Schick (7 Goals) Spain A. Grimaldo (7 Goals)
Best assists
Netherlands T. Reijnders (5 Assists)
Best assists
Spain A. Garcia (4 Assists)
Netherlands E. Poku (4 Assists)
Spain A. Grimaldo (4 Assists)

Manchester City and Bayer Leverkusen Stats in Champions League

Manchester City
Manchester City
Bayer Leverkusen
Bayer Leverkusen
75%
Wins
25%
25%
Draw
50%
0%
Losses
25%
3.25
Total goals per match
4
2.5
Goals scored per match
1.5
0.75
Goals conceded per match
2.5
50%
Over 2.5
50%
50%
Under 2.5
50%
50%
BTTS
75%
50%
Clean Sheet
25%

Manchester City - Bayer Leverkusen Key Points

  1. Manchester City are yet to lose in the league phase.
  2. Manchester City have won both of their home games in the Champions League this season.
  3. Bayer Leverkusen have only won one of their four league phase fixtures.
  4. Only five clubs have conceded more league phase goals than Leverkusen.
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Our Manchester City vs Bayer Leverkusen Prediction

Manchester City's form in the Champions League has been solid this season. Three of their four games have ended in victory and they really should have won their away game in Monaco to make it four.  Both of their home games have been won with six goals scored.

Bayer Leverkusen only earned two points from their first three games and were hammered 7-2 at home by PSG. They breathed life back into their campaign with three points at Benfica.  Our main Manchester City v Bayer Leverkusen prediction is Manchester City wins and leads at half and full time.

Prediction :

 

Half-time/Full-time: Manchester City/Manchester City

 
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Manchester City vs Bayer Leverkusen - Other Interesting Predictions

Erling Haaland to score the first goal

Odds 3.1
Erling Haaland drew a blank at the weekend but has been in top goalscoring form this season both for his club and Norway. In the Champions League, he has scored the first goal of the match in three of City's four games.
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Manchester City vs Bayer Leverkusen match : Frequently asked questions

This Champions League game between Manchester City and Bayer Leverkusen is being played on Tuesday November 25. It is an evening kick-off and the match is due to get underway at 20:00 UK time.
It's City's third home game in the league phase and will be played at the Etihad in Manchester.
A subscription to TNT Sports is required for UK viewers to be able to watch this game live. You can go to our Champions League livescore for help with your in-play bets. There you'll find live text commentary plus updated odds and statistics.

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Manchester City vs Bayer Leverkusen Prediction

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