Philadelphia 76ers vs Cleveland Cavaliers Prediction & Betting Tips - NBA
USA - NBA
New customers only | Commercial content | 18+ age limit | T&Cs apply
by Geoffrey Ejiga | in NBA Predictions
Cleveland arrive in Philadelphia for their opener, and our 76ers vs Cavaliers match prediction in this NBA clash is a home win. The 76ers already have a game behind them, having won 106-100 at the Knicks in their opener. While Cleveland begins their regular season at Wells Fargo Center.
The Cavaliers won only two of their final nine road games last season. The seven defeats included three in Toronto and two each in Detroit and New York. Cleveland also went 1-2 in the preseason, conceding 124 and 132 points in the two defeats. Those numbers suggest a visiting side still finding its rhythm.
However, the head-to-head record does lean toward the Cavaliers, who won six of the last seven meetings. The latest ended 115-101 in Cleveland's favor. That record matters less now that Philadelphia have signed both Lebron James and Jaylen Brown, in a fresh season where the 76ers have already started with a win.
We still keep in mind that Philadelphia's last eight home games of last season produced only three wins, so a close finish is likely.
Limited Offer. Currently at Stake
Philadelphia 76ers v Cleveland Cavaliers Best Betting Odds
| Bookmaker | 1 | 2 | Bonus |
|---|---|---|---|
|
|
1.64 | 2.34 |
|
|
|
1.62 | 2.30 |
|
|
|
1.65 | 2.30 |
|
|
|
1.67 | 2.22 |
|
|
|
1.67 | 2.22 |
|
Pre-register for our Member Area: win €500!
Who will win the Philadelphia 76ers vs Cleveland Cavaliers Basketball game?
Our prediction for the Philadelphia 76ers vs Cleveland Cavaliers match is: Philadelphia 76ers win.
The best winner predictions and betting odds for the Philadelphia 76ers vs Cleveland Cavaliers game on 22/10/2026 of the current NBA season:
- Philadelphia 76ers has a 51.33% chance to pick up the win against Cleveland Cavaliers according to Shangrila ⭐ with the odds of 1.72.
- There is a probability of 48.67% ⭐ for Cleveland Cavaliers to win vs Philadelphia 76ers with odds of 2.34 at 1xbet.
Philadelphia 76ers vs Cleveland Cavaliers Form
Philadelphia 76ers and Cleveland Cavaliers's standings in the NBA
| Teams | % | P | W | L | Series |
|---|---|---|---|---|---|
|
1
|
1 | 1 | 1 | 0 | 1 |
|
15
|
0 | 0 | 0 | 0 |
Philadelphia 76ers and Cleveland Cavaliers Last Matches
3/6 (50%)
3/6 (50%)
20 Oct 2026 - NBA
18 Jul 2026 - NBA Summer League
15 Jul 2026 - NBA Summer League
14 Jul 2026 - NBA Summer League
11 Jul 2026 - NBA Summer League
9 Jul 2026 - NBA Summer League
3/6 (50%)
3/6 (50%)
15 Jul 2026 - NBA Summer League
11 Jul 2026 - NBA Summer League
9 Jul 2026 - NBA Summer League
10 May 2026 - NBA
8 May 2026 - NBA
30 Apr 2026 - NBA
2/6 (33%)
4/6 (67%)
20 Oct 2026 - NBA
18 Jul 2026 - NBA Summer League
14 Jul 2026 - NBA Summer League
6 May 2026 - NBA
4 May 2026 - NBA
2 May 2026 - NBA
3/6 (50%)
3/6 (50%)
17 Jul 2026 - NBA Summer League
15 Jul 2026 - NBA Summer League
13 Jul 2026 - NBA Summer League
12 Jul 2026 - NBA Summer League
10 Jul 2026 - NBA Summer League
25 May 2026 - NBA
3/6 (50%)
3/6 (50%)
17 Jul 2026 - NBA Summer League
15 Jul 2026 - NBA Summer League
13 Jul 2026 - NBA Summer League
25 May 2026 - NBA
23 May 2026 - NBA
15 May 2026 - NBA
2/6 (33%)
4/6 (67%)
12 Jul 2026 - NBA Summer League
10 Jul 2026 - NBA Summer League
21 May 2026 - NBA
19 May 2026 - NBA
17 May 2026 - NBA
13 May 2026 - NBA
Philadelphia 76ers vs Cleveland Cavaliers Stats: Head to Head (H2H)
17 %
83 %
9 Mar 2026 - NBA
16 Jan 2026 - NBA
14 Jan 2026 - NBA
5 Nov 2025 - NBA
24 Jan 2025 - NBA
21 Dec 2024 - NBA
Players list
T. Maxey
V. Edgecombe
L. James
J. Robinson
M. Thomas
M. Branham
R. Minix
Substitutes
K. Caldwell-Pope
A. Simons
C. Love
J. Edwards
L. Philon
J. Walker
D. Goodwin
S. East II
I. Martinez
X. Lee
R. Agee
T. Spillers
Philadelphia 76ers - Cleveland Cavaliers Key Points
- The 76ers won their season opener 106-100 at the Knicks.
- The Cavaliers won only two of their final nine road games last season.
- The Cavaliers won six of the last seven meetings, with the latest a 115-101 win.
- The 76ers now field Lebron James and Jalyen Brown, alongside Joel Embiid and VJ Edgecombe.
Limited Offer. Currently at Stake
Our Philadelphia 76ers vs Cleveland Cavaliers Prediction
Philadelphia hosts Cleveland after a 106-100 opening win at the Knicks. The Cavaliers haven’t seen action yet, but they notably lost seven of their final nine road games last season.
Cleveland won six of the last seven meetings, but this is a brand new 76ers' team with a competent home record. The margin may be thin, but it should be a Philly win either way. Hence, our 76ers vs Cavaliers prediction is that the Philadelphia 76ers win.
Use £/€50 free bets for the Philadelphia 76ers vs. Cleveland Cavaliers game!

Are you planning to bet on the upcoming match between Philadelphia 76ers and Cleveland Cavaliers? Why not take advantage of the free bets from Bet365? Use our promo code STYVIP1 and open your account. Bet365 offers a welcome package of €/£50 free bet credits if you bet €/£10 as a new player.
Try your luck on this year's NBA! You need to make your qualifying bet of €/£10 within 30 days of opening an account and this can be on any sport with at least one selection priced at 1.2 (1/5) or bigger.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.