Betis vs Panathinaikos Athens Prediction & Betting Tips - Europa League
Europe - Europa League
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by Devesh Jaganath | in Europa League Predictions
A sea of green and white will fill Estadio de La Cartuja on Thursday night when Real Betis welcome Panathinaikos for a decisive Europa League Round of 16 clash. The winner of this tie between Los Verdiblancos and Oi Prasinoi will face either Ferencvaros or Braga in the quarter-final. Check out our match prediction below!
Rafael Benitez’s side arrives in Sevilla this week with a 1-0 advantage, thanks to a penalty in the dying moments of a tightly contested first leg. The Spanish tactician has now suffered only one defeat in his last 18 UEL matches (W8 D9), dating back over a decade against Napoli in 2014-15.
Manuel Pellegrini will undoubtedly have a plan up his sleeve here, and the rivalry between himself and Benitez is locked level, with each winning two (D1) of their past five encounters. The hosts have been near-flawless at home in this competition, with only Nottingham Forest leaving Estadio de La Cartuja with a point this season. Let’s get into the key stats!
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Betis v Panathinaikos Athens Best Betting Odds
| Bookmaker | 1 | X | 2 | Bonus up to |
|---|---|---|---|---|
|
1.43 | 4.9 | 7.8 |
|
|
1.4 | 4.5 | 8.5 |
|
|
1.4 | 4.5 | 8.5 |
|
|
1.4 | 4.5 | 8.5 |
|
|
1.41 | 4.7 | 8 |
|
What is the prediction for the football match between Betis and Panathinaikos Athens?
Our prediction for the Betis vs Panathinaikos Athens match is: Panathinaikos +2 European handicap.
Probabilities according to our algorithm* of possible 1X2 football predictions and best odds for the match on 19/03/2026 between Betis and Panathinaikos Athens in Europa League :
- The Sportytrader ⭐ algorithm estimates a probability of 30.39% for a win of Betis against Panathinaikos Athens with odds of 1.45 at LSbet.
- The probability according to Sportytrader ⭐ for a draw between Betis vs Panathinaikos Athens is 30.73% with odds of 4.9 at Stake.
- Our prediction model gives a 38.88% chance ⭐ for a win of Panathinaikos Athens vs Betis with odds of 8.69 at 888Starz.
Betis - Panathinaikos Athens Prediction and Best Odds:
| Betis Panathinaikos Athens Prediction | Probability | Odds |
|---|---|---|
| Panathinaikos Athens wins | 38.88% | 8.69 at 888Starz |
| Under 2.5 | 59.99% | 2.3 at 888Starz |
| Both Team To Score: No | 52.08% | |
| Half-time: Draw / Full-time: Panathinaikos Athens | 16.54% | 15 at Bet365 |
Betis vs Panathinaikos Athens Form
Betis and Panathinaikos Athens Last Matches
1/6 (17%)
3/6 (50%)
2/6 (33%)
Average stats (Last 6 matchs)
15 Mar 2026 - LaLiga
12 Mar 2026 - Europa League
8 Mar 2026 - LaLiga
1 Mar 2026 - LaLiga
21 Feb 2026 - LaLiga
15 Feb 2026 - LaLiga
2/6 (33%)
3/6 (50%)
1/6 (17%)
Average stats (Last 6 matchs)
15 Mar 2026 - LaLiga
1 Mar 2026 - LaLiga
21 Feb 2026 - LaLiga
5 Feb 2026 - Copa del Rey
1 Feb 2026 - LaLiga
29 Jan 2026 - Europa League
2/6 (33%)
0/6 (0%)
4/6 (67%)
Average stats (Last 6 matchs)
12 Mar 2026 - Europa League
8 Mar 2026 - LaLiga
15 Feb 2026 - LaLiga
8 Feb 2026 - LaLiga
25 Jan 2026 - LaLiga
22 Jan 2026 - Europa League
4/6 (67%)
2/6 (33%)
0/6 (0%)
Average stats (Last 6 matchs)
15 Mar 2026 - Superleague
12 Mar 2026 - Europa League
8 Mar 2026 - Superleague
4 Mar 2026 - Superleague
1 Mar 2026 - Superleague
26 Feb 2026 - Europa League
3/6 (50%)
3/6 (50%)
0/6 (0%)
Average stats (Last 6 matchs)
15 Mar 2026 - Superleague
12 Mar 2026 - Europa League
4 Mar 2026 - Superleague
1 Mar 2026 - Superleague
19 Feb 2026 - Europa League
15 Feb 2026 - Superleague
3/6 (50%)
2/6 (33%)
1/6 (17%)
Average stats (Last 6 matchs)
8 Mar 2026 - Superleague
26 Feb 2026 - Europa League
22 Feb 2026 - Superleague
11 Feb 2026 - Greece Cup
8 Feb 2026 - Superleague
25 Jan 2026 - Superleague
Betis vs Panathinaikos Athens Stats: Head to Head (H2H)
0 %
0 %
100 %
Average stats (last H2H results)
12 Mar 2026 - Europa League
Betis - Panathinaikos Athens: Form Analysis
Real Betis had an excellent League Phase in this season’s Europa League, clinching fourth place with 17 points (W5 D2 L1) to progress to the Round of 16 before their loss in Athens last week.
However, El Glorioso have not been in the best form of late, and after drawing 1-1 with Celta Vigo at the weekend, they are now winless in their last five matches across all competitions (D3 L2).
Each of the hosts’ three draws during this period have come at home, where they are now winless in four games, a massive drop-off after winning their preceding five matches at this venue.
Betis have scored two or more goals in seven of their last 10 home games in all competitions!
Meanwhile, after losing two of their first three UEL games this season, Panathinaikos took nine points from their final five League Phase matches (W2 D3) and are now unbeaten in six in this competition.
Trifylli were held to a goalless draw by Panetolikos in the Super League at the weekend, which ended their six-match win streak but extended their unbeaten run in all competitions to nine (W6 D3).
The visitors got past Viktoria Plzen on penalties in the Knockout Playoffs on the road, and have only lost one of their five away games in the UEL proper this season - a 3-1 defeat to Feyenoord on Matchday 3.
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Betis against Panathinaikos Athens Lineups: Starting 11
Formation : 4 - 4 - 2
Formation : 3 - 4 - 3
Substitutes
A. Valles
Adrian
DefenderJ. Firpo
D. Gomez
MidfielderA. Ortiz
A. Fidalgo
M. Roca
R. Riquelme
N. Deossa
S. Altimira
C. Avila
C. Bakambu
C. Geitonas
K. Kotsaris
DefenderA. Touba
MidfielderA. Gnezda Cerin
M. Siopis
P. Chirivella
G. Kotsiras
M. Pantovic
S. Andino
K. Swiderski
F. Djuricic
Missing players
D. Llorente
MidfielderIsco
G. Lo Celso
Betis & Panathinaikos Athens Squad Analysis
Antony could be one to watch for Betis this week. The former Manchester United winger has been the team’s most effective player in this competition with seven goal contributions (four goals, three assists) and a shot accuracy of 40%.
Diego Llorente was sent off for the tackle that led to the crucial penalty in the first leg, meaning he is suspended for this match. Marc Bartra is likely to step into central defence in his absence.
Natan was hooked at the break in the first leg with a knock and is a doubt, along with Giovani Lo Celso. Former Real Madrid man Isco is ruled out until the end of the month with a thigh injury.
How will Panathinaikos fare without their UEL joint-top scorer Anass Zaroury?
The Lens loanee has netted four goals in this season’s competition but was sent off just before the hour mark after picking up two bookable offences in the space of 10 minutes at home last week.
Zaroury’s absence on the flank could open the door for the highly rated Argentine youngster Santino Andino to make his first start in Europe for the Greens since arriving from Godoy Cruz in January.
The visitors will be missing at least four players through injury for this decisive leg, including Cyriel Dessers, Gorgeous Kyriopoulos, Giannis Kotsiras and Erik Palmer-Brown.
Most goals and assists
Betis
Panathinaikos Athens
Antony
(6 Goals)
A. Zaroury
(4 Goals)
, 
K. Swiderski
(4 Goals)
Antony
(3 Assists)
T. Bakasetas
(2 Assists)
,
Tete
(2 Assists)
, 
V. Taborda
(2 Assists)
Betis - Panathinaikos Athens Key Points
- Real Betis are winless in their last five matches in all competitions.
- Real Betis have failed to keep a clean sheet in their last six home matches.
- Panathinaikos are unbeaten in their last six UEL games.
- Panathinaikos are unbeaten in their last nine matches across all competitions.
- Panathinaikos have only conceded 2+ goals in one of their last six away games.
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Our Betis vs Panathinaikos Athens Prediction
Real Betis are massive favourites for this home leg, but they have not been anywhere close to their best form of late, currently winless in their last five matches across all competitions and their last four at this venue.
Panathinaikos showed last week that they can be tough to break down when they implement a low block, as they did after going down to 10 men. We’re expecting the visitors to prioritise keeping a clean sheet in this fixture. Therefore, our Real Betis vs Panathinaikos prediction is Panathinaikos +2 European handicap.
Betis vs Panathinaikos Athens Alternative Predictions
Less than 2.5 goals
Four of Real Betis’ last five games have ended with fewer than 2.5 goals scored, and they conceded fewer than a goal per 90 during the League Phase of this competition. Panathinaikos have kept clean sheets in their last two matches ahead of this one.
Betis wins
While we are expecting the visitors to put up a stern test, we still fancy Betis to win this match at home, where they have only lost one of their last nine games. Additionally, Panathinaikos have only won two of their last 19 games against Spanish opposition in UEFA competitions.
Last Minute: Pre-match odds analysis Betis Panathinaikos Athens
| Betis vs Panathinaikos Athens | Opening odds | Pre-match odds | Odds Movements |
|---|---|---|---|
| Betis wins | 1.42 | 1.45 | +2.1% |
| Draw | 4.6 | 4.9 | +6.5% |
| Panathinaikos Athens wins | 7.75 | 8.69 | +12.1% |
After kick-off, the latest odds movements show that:
- Panathinaikos Athens is most likely to win
- The odds for this bet have increased by 12.1% since opening
- The probability of this result was 12.9% and is now 11.5% (-1.4%)
Betis vs Panathinaikos Athens - FAQs
The Europa League Round of 16 second leg between Real Betis and Panathinaikos will take place on March 19 at 20:00 UTC.
The Europa League Round of 16 second leg between Real Betis and Panathinaikos will be played at Estadio de La Cartuja in Sevilla.
The Europa League Round of 16 second leg between Real Betis and Panathinaikos will be broadcast on Telefonica in Spain and Antenna TV in Greece. UK viewers can tune in to TNT Sports.
Alternatively, you can follow all the action on our Europa League livescore tool.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
