Jacksonville Jaguars vs Cleveland Browns Prediction & Picks - NFL

USA - NFL

Jacksonville Jaguars
9/13/26 13:00
Cleveland Browns

Prediction:

 

The Jaguars -8.0 points

-112
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 by Lou Aguila in NFL Picks

The Jacksonville Jaguars open their 2026 NFL season as a rock-solid 8.0-point favorite over the rebuilding Cleveland Browns.

Current Form:

The Jacksonville Jaguars have brought back the whole gang along with the same approach on both ends of the field. After winning the AFC South last year, Jacksonville hopes to make a bigger splash this season by reclaiming the division title and staging a deep postseason run. Quarterback Trevor Lawrence returns for his sixth season with the Jaguars, looking to deliver another prolific campaign after passing for 4,007 yards with 29 touchdowns and 12 interceptions in 2025.

The Cleveland Browns only won 5 of their 17 matches last season. The Browns are bringing back quarterback Deshaun Watson, who will make his return after a second Achilles tear. Watson is currently competing with Shedeur Sanders for the starting quarterback spot, but these two talented signal-callers give the Browns depth in the most important position in football.

The Matchup: The Browns have beaten the Jaguars in their last three meetings, though their last head-to-head match happened two years ago in 2024.

Jacksonville Jaguars vs Cleveland Browns Form

Table

Teams Pts P W L
3 Cleveland Browns
0 0 0 0
3 Jacksonville Jaguars
0 0 0 0

Jacksonville Jaguars and Cleveland Browns Latest Matches

Jacksonville Jaguars
Jacksonville Jaguars Latest matches
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Jan 11, 2026 - NFL

Jacksonville Jaguars
24 :  27
Buffalo Bills

Jan 4, 2026 - NFL

Jacksonville Jaguars
41 :  7
Tennessee Titans

Dec 28, 2025 - NFL

Indianapolis Colts
17 :  23
Jacksonville Jaguars

Dec 21, 2025 - NFL

Denver Broncos
20 :  34
Jacksonville Jaguars

Dec 14, 2025 - NFL

Jacksonville Jaguars
48 :  20
New York Jets

Dec 7, 2025 - NFL

Jacksonville Jaguars
36 :  19
Indianapolis Colts
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jan 11, 2026 - NFL

Jacksonville Jaguars
24 :  27
Buffalo Bills

Jan 4, 2026 - NFL

Jacksonville Jaguars
41 :  7
Tennessee Titans

Dec 14, 2025 - NFL

Jacksonville Jaguars
48 :  20
New York Jets

Dec 7, 2025 - NFL

Jacksonville Jaguars
36 :  19
Indianapolis Colts

Nov 16, 2025 - NFL

Jacksonville Jaguars
35 :  6
Los Angeles Chargers

Oct 19, 2025 - NFL

Jacksonville Jaguars
7 :  35
Los Angeles Rams
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Dec 28, 2025 - NFL

Indianapolis Colts
17 :  23
Jacksonville Jaguars

Dec 21, 2025 - NFL

Denver Broncos
20 :  34
Jacksonville Jaguars

Nov 30, 2025 - NFL

Tennessee Titans
3 :  25
Jacksonville Jaguars

Nov 23, 2025 - NFL

Arizona Cardinals
24 :  27
Jacksonville Jaguars

Nov 9, 2025 - NFL

Houston Texans
36 :  29
Jacksonville Jaguars

Nov 2, 2025 - NFL

Las Vegas Raiders
29 :  30
Jacksonville Jaguars
Cleveland Browns
Cleveland Browns Latest matches
L L L L W W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jan 4, 2026 - NFL

Cincinnati Bengals
18 :  20
Cleveland Browns

Dec 28, 2025 - NFL

Cleveland Browns
13 :  6
Pittsburgh Steelers

Dec 21, 2025 - NFL

Cleveland Browns
20 :  23
Buffalo Bills

Dec 14, 2025 - NFL

Chicago Bears
31 :  3
Cleveland Browns

Dec 7, 2025 - NFL

Cleveland Browns
29 :  31
Tennessee Titans

Nov 30, 2025 - NFL

Cleveland Browns
8 :  26
San Francisco 49ers
W L L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Dec 28, 2025 - NFL

Cleveland Browns
13 :  6
Pittsburgh Steelers

Dec 21, 2025 - NFL

Cleveland Browns
20 :  23
Buffalo Bills

Dec 7, 2025 - NFL

Cleveland Browns
29 :  31
Tennessee Titans

Nov 30, 2025 - NFL

Cleveland Browns
8 :  26
San Francisco 49ers

Nov 16, 2025 - NFL

Cleveland Browns
16 :  23
Baltimore Ravens

Oct 19, 2025 - NFL

Cleveland Browns
31 :  6
Miami Dolphins
L L L W L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jan 4, 2026 - NFL

Cincinnati Bengals
18 :  20
Cleveland Browns

Dec 14, 2025 - NFL

Chicago Bears
31 :  3
Cleveland Browns

Nov 23, 2025 - NFL

Las Vegas Raiders
10 :  24
Cleveland Browns

Nov 9, 2025 - NFL

New York Jets
27 :  20
Cleveland Browns

Oct 26, 2025 - NFL

New England Patriots
32 :  13
Cleveland Browns

Oct 12, 2025 - NFL

Pittsburgh Steelers
23 :  9
Cleveland Browns

Jacksonville Jaguars against Cleveland Browns : Head to Head (H2H)

Jacksonville Jaguars

0 %

Cleveland Browns

100 %

Sep 15, 2024 - NFL

Jacksonville Jaguars
13 :  18
Cleveland Browns
Jacksonville Jaguars vs Cleveland Browns Picks

Jacksonville Jaguars - Cleveland Browns Key Points

  1. The Jaguars are 8-1 ATS in their last 9 games overall.
  2. The Jaguars are 7-1 ATS in their last 8 vs. AFC.
  3. Browns QB Deshaun Watson is returning from an Achilles Heel injury.
  4. The Browns are 3-7 in their last 10 games.

Our Jacksonville Jaguars vs Cleveland Browns Prediction

Key Stats: The Jaguars are 5-1 ATS in their last 6 games as a home favorite. Also, Jacksonville blanked the Tampa Bay Buccaneers, 19-0, in their final game of the preseason, showcasing their scoring defense that ranked 8th in the league at 19.8 points per game in 2025.

What to Expect: The Jaguars dominate the Browns at home. QB Trevor Lawrence will put up strong numbers in his season debut despite facing one of the most fearsome pass-rushing units in football, led by Defensive Player of the Year Myles Garrett.

The Jaguars are projected to put up at least 26.2 points per game this season, while the Browns are expected to average 19.0 points per game.

These projections make Jacksonville worth a gamble at -112 to cover 8.0 points, given that the Browns don’t have much firepower in their arsenal to go toe-to-toe with the Jaguars' high-octane offense.

Fearless Forecast: Jaguars win 31-17

Our betting prediction for the Cleveland Browns vs. the Jacksonville Jaguars: The Jaguars -8.0 points

Prediction:

 

The Jaguars -8.0 points

-112
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.