Detroit Lions vs New Orleans Saints Prediction & Picks - NFL
USA - NFL
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Bill Christy | in NFL Picks
The 2025-2026 season was disappointing for both the Detroit Lions and the New Orleans Saints. The Saints finished with a 6-11 mark and while the expectations were low, the 6 wins was still a disappointment. For the Lions, they had high hopes but failed to live up to the hype. They finished 9-8 and missed out on the postseason. On Sunday afternoon, these two teams will kickoff their 2025-2026 seasons as the Lions will play hosts.
This season, the hype in Detroit is back to a fever pitch and many expect them to make a large improvement in the win column this season. They have arguably the most versatile and explosive running backs in the league in Jahmyr Gibbs. He will get an even larger load this season as they lost David Montgomery to Houston in the offseason. However, Gibbs on the ground and Amon-Ra St. Brown through the air is enough weapons for any offense.
The Saints are not expected to be a true contender this season. However, they did bring in Travis Etienne from Jacksonville to make up for the aging and injury-ridden Alvin Kamara. Tyler Shough is set to be the starter and should provide some juice and youth to the offense. He will have one of the top receivers in the league to throw to in Chris Olave. Brandon Staley made some additions to the defense and they should be improved from last season
Limited Offer. Currently at DraftKings
Detroit Lions vs New Orleans Saints Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
3
|
0 | 0 | 0 | 0 |
|
3
|
0 | 0 | 0 | 0 |
Detroit Lions and New Orleans Saints Latest Matches
2/6 (33%)
4/6 (67%)
Jan 4, 2026 - NFL
Dec 25, 2025 - NFL
Dec 21, 2025 - NFL
Dec 14, 2025 - NFL
Dec 4, 2025 - NFL
Nov 27, 2025 - NFL
3/6 (50%)
3/6 (50%)
Dec 21, 2025 - NFL
Dec 4, 2025 - NFL
Nov 27, 2025 - NFL
Nov 23, 2025 - NFL
Nov 2, 2025 - NFL
Oct 20, 2025 - NFL
2/6 (33%)
4/6 (67%)
Jan 4, 2026 - NFL
Dec 25, 2025 - NFL
Dec 14, 2025 - NFL
Nov 16, 2025 - NFL
Nov 9, 2025 - NFL
Oct 12, 2025 - NFL
4/6 (67%)
2/6 (33%)
Jan 4, 2026 - NFL
Dec 28, 2025 - NFL
Dec 21, 2025 - NFL
Dec 14, 2025 - NFL
Dec 7, 2025 - NFL
Nov 30, 2025 - NFL
3/6 (50%)
3/6 (50%)
Dec 21, 2025 - NFL
Dec 14, 2025 - NFL
Nov 23, 2025 - NFL
Oct 26, 2025 - NFL
Oct 12, 2025 - NFL
Oct 5, 2025 - NFL
3/6 (50%)
3/6 (50%)
Jan 4, 2026 - NFL
Dec 28, 2025 - NFL
Dec 7, 2025 - NFL
Nov 30, 2025 - NFL
Nov 9, 2025 - NFL
Nov 2, 2025 - NFL
Detroit Lions against New Orleans Saints : Head to Head (H2H)
100 %
0 %
Dec 3, 2023 - NFL
Detroit Lions - New Orleans Saints Key Points
- Lions are 1-3 ATS in their last 4 games.
- Lions are 1-4 ATS in their last 5 at home as favorites.
- Saints are 4-0 ATS in their last 4 games as a road underdog.
- Saints are 6-0 ATS in their last 6 games overall.
Limited Offer. Currently at DraftKings
Our Detroit Lions vs New Orleans Saints Prediction
The Saints were one of the best teams against the spread towards the end of last season. We like them to continue that type of play to start the season here in Detroit. While the Lions are one of the best offenses in the league, we believe the defense will struggle against this revitalized Saints offense in the opener. The Lions should pull out the win but we expect the Saints to cover the number.
Our prediction for Detroit Lions vs New Orleans Saints: New Orleans +7
A Welcome Bonus for Detroit Lions vs New Orleans Saints!

Looking to place a bet on Detroit Lions vs New Orleans Saints? For this NFL match, DraftKings will treat you to an exclusive offer: $200 in bonus bets, no promo code needed! Take advantage while you still can!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.