Denver Broncos vs Jacksonville Jaguars Prediction & Picks - NFL

USA - NFL

Denver Broncos
9/20/26 16:05
Jacksonville Jaguars

Prediction:

 

Jacksonville Jaguars win the match

+130
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 by Carlos Zabala in NFL Picks

The Jaguars were one of the most dominant teams in Week 1, defeating the Browns 34-10. Trevor Lawrence threw four touchdowns and completed 18 of 23 passes for 245 yards, with no interceptions. Jacksonville now prepares for their visit to Denver, where they are the underdogs at +127 odds in the sportsbooks.

The Jaguars' strong performance isn't limited to Week 1; they had also appeared in previous playoffs and during the regular season and now boast a nine-game winning streak. In Week 16 of 2025, these Jaguars defeated the Broncos 34-20 at Empower Field.

The Broncos, on the other hand, are coming off a disappointing first week, losing 10-31 to the Chiefs. In that loss, Bo Nix, returning from injury, finished with 131 yards, one touchdown, and one interception, while also being sacked four times.

Denver Broncos vs Jacksonville Jaguars Form

Table

Teams Pts P W L
5 Jacksonville Jaguars
1 1 1 0
28 Denver Broncos
0 1 0 1

Denver Broncos and Jacksonville Jaguars Latest Matches

Denver Broncos
Denver Broncos Latest matches
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 14, 2026 - NFL

Kansas City Chiefs
31 :  10
Denver Broncos

Jan 25, 2026 - NFL

Denver Broncos
7 :  10
New England Patriots

Jan 17, 2026 - NFL

Denver Broncos
33 :  30
Buffalo Bills

Jan 4, 2026 - NFL

Denver Broncos
19 :  3
Los Angeles Chargers

Dec 25, 2025 - NFL

Kansas City Chiefs
13 :  20
Denver Broncos

Dec 21, 2025 - NFL

Denver Broncos
20 :  34
Jacksonville Jaguars
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jan 25, 2026 - NFL

Denver Broncos
7 :  10
New England Patriots

Jan 17, 2026 - NFL

Denver Broncos
33 :  30
Buffalo Bills

Jan 4, 2026 - NFL

Denver Broncos
19 :  3
Los Angeles Chargers

Dec 21, 2025 - NFL

Denver Broncos
20 :  34
Jacksonville Jaguars

Dec 14, 2025 - NFL

Denver Broncos
34 :  26
Green Bay Packers

Nov 16, 2025 - NFL

Denver Broncos
22 :  19
Kansas City Chiefs
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 14, 2026 - NFL

Kansas City Chiefs
31 :  10
Denver Broncos

Dec 25, 2025 - NFL

Kansas City Chiefs
13 :  20
Denver Broncos

Dec 7, 2025 - NFL

Las Vegas Raiders
17 :  24
Denver Broncos

Nov 30, 2025 - NFL

Washington Commanders
26 :  27
Denver Broncos

Nov 2, 2025 - NFL

Houston Texans
15 :  18
Denver Broncos

Oct 12, 2025 - NFL

New York Jets
11 :  13
Denver Broncos
Jacksonville Jaguars
Jacksonville Jaguars Latest matches
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 13, 2026 - NFL

Jacksonville Jaguars
34 :  10
Cleveland Browns

Jan 11, 2026 - NFL

Jacksonville Jaguars
24 :  27
Buffalo Bills

Jan 4, 2026 - NFL

Jacksonville Jaguars
41 :  7
Tennessee Titans

Dec 28, 2025 - NFL

Indianapolis Colts
17 :  23
Jacksonville Jaguars

Dec 21, 2025 - NFL

Denver Broncos
20 :  34
Jacksonville Jaguars

Dec 14, 2025 - NFL

Jacksonville Jaguars
48 :  20
New York Jets
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 13, 2026 - NFL

Jacksonville Jaguars
34 :  10
Cleveland Browns

Jan 11, 2026 - NFL

Jacksonville Jaguars
24 :  27
Buffalo Bills

Jan 4, 2026 - NFL

Jacksonville Jaguars
41 :  7
Tennessee Titans

Dec 14, 2025 - NFL

Jacksonville Jaguars
48 :  20
New York Jets

Dec 7, 2025 - NFL

Jacksonville Jaguars
36 :  19
Indianapolis Colts

Nov 16, 2025 - NFL

Jacksonville Jaguars
35 :  6
Los Angeles Chargers
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Dec 28, 2025 - NFL

Indianapolis Colts
17 :  23
Jacksonville Jaguars

Dec 21, 2025 - NFL

Denver Broncos
20 :  34
Jacksonville Jaguars

Nov 30, 2025 - NFL

Tennessee Titans
3 :  25
Jacksonville Jaguars

Nov 23, 2025 - NFL

Arizona Cardinals
24 :  27
Jacksonville Jaguars

Nov 9, 2025 - NFL

Houston Texans
36 :  29
Jacksonville Jaguars

Nov 2, 2025 - NFL

Las Vegas Raiders
29 :  30
Jacksonville Jaguars

Denver Broncos against Jacksonville Jaguars : Head to Head (H2H)

Denver Broncos

0 %

Jacksonville Jaguars

100 %

Dec 21, 2025 - NFL

Denver Broncos
20 :  34
Jacksonville Jaguars
Denver Broncos vs Jacksonville Jaguars Picks

Denver Broncos - Jacksonville Jaguars Key Points

  1. Denver missed 28 tackles in the loss to the Chiefs
  2. The Jaguars led 31-0 in their victory against the Browns
  3. The Jaguars converted 23 first downs in their win against the Browns
  4. The Jaguars' defense recorded 5 sacks in their Week 1 victory

Our Denver Broncos vs Jacksonville Jaguars Prediction

This means that Sunday's matchup pits two quarterbacks with completely different trajectories against each other: Lawrence is coming off a highly effective offensive performance, and while the Broncos relied heavily on Nix's passing game, he wasn't able to make as much of an impact as he would have liked.

It certainly looks like a good opportunity to pick the Jaguars as underdogs in the betting odds.

Our prediction for Broncos vs Jaguars is: Jaguars ML.

Prediction:

 

Jacksonville Jaguars win the match

+130
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.