Inter Miami vs Chicago Fire Prediction & Picks - Major League Soccer

USA - Major League Soccer

Inter Miami
7/22/26 19:30
Chicago Fire

Prediction:

 

Under 3.5 Goals

+110
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 by Mikaella McIntosh | in Major League Soccer Picks

There’s a big clash to recommence the MLS season in the Eastern Conference this Wednesday, with two of the top three teams in the table, Inter Miami and Chicago Fire, take to the stage at Nu Stadium. The early market strongly favors a high-scoring meeting, but there are some factors that have been overlooked to make Under 3.5 Goals a very good value bet. 

Such a meeting between two of the best teams in the MLS this season would scream tons of goals. However, track records of similar games this season including the two teams at hand suggest otherwise. 

When The Fire met with Nashville at this stadium, the other top team in the Eastern Conference, only one goal was recorded. Crucially, Inter Miami have also faced Nashville twice, one finishing with two goals, the other zero. This leads us to conclude that Under 3.5 Goals is a very good bet.

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Inter Miami vs Chicago Fire Form

Table

Teams Pts P W D L GD
4 Inter Miami
31 15 9 4 2 +11
6 Chicago Fire
26 14 8 2 4 +11

Inter Miami and Chicago Fire Latest Matches

Inter Miami
Inter Miami Latest matches
D L W W W W
Victories

4/6 (67%)

Draw

1/6 (17%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

5.83 Total goals
83% BTTS
3.5 Goals scored
2.33 Goals conceded
67% Over 2.5
33% Under 2.5

May 24, 2026 - Major League Soccer

Inter Miami
6 :  4
Philadelphia Union

May 17, 2026 - Major League Soccer

Inter Miami
2 :  0
Portland Timbers

May 13, 2026 - Major League Soccer

FC Cincinnati
3 :  5
Inter Miami

May 9, 2026 - Major League Soccer

Toronto FC
2 :  4
Inter Miami

May 2, 2026 - Major League Soccer

Inter Miami
3 :  4
Orlando City SC

Apr 25, 2026 - Major League Soccer

Inter Miami
1 :  1
New England Revolution
D D D L W W
Victories

2/6 (33%)

Draw

3/6 (50%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

4.83 Total goals
83% BTTS
2.67 Goals scored
2.17 Goals conceded
67% Over 2.5
33% Under 2.5

May 24, 2026 - Major League Soccer

Inter Miami
6 :  4
Philadelphia Union

May 17, 2026 - Major League Soccer

Inter Miami
2 :  0
Portland Timbers

May 2, 2026 - Major League Soccer

Inter Miami
3 :  4
Orlando City SC

Apr 25, 2026 - Major League Soccer

Inter Miami
1 :  1
New England Revolution

Apr 11, 2026 - Major League Soccer

Inter Miami
2 :  2
New York Red Bulls

Apr 4, 2026 - Major League Soccer

Inter Miami
2 :  2
Austin FC
D W W W W W
Victories

5/6 (83%)

Draw

1/6 (17%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

4.33 Total goals
67% BTTS
2.83 Goals scored
1.5 Goals conceded
67% Over 2.5
33% Under 2.5

May 13, 2026 - Major League Soccer

FC Cincinnati
3 :  5
Inter Miami

May 9, 2026 - Major League Soccer

Toronto FC
2 :  4
Inter Miami

Apr 22, 2026 - Major League Soccer

Real Salt Lake
0 :  2
Inter Miami

Apr 18, 2026 - Major League Soccer

Colorado Rapids
2 :  3
Inter Miami

Mar 22, 2026 - Major League Soccer

New York City
2 :  3
Inter Miami

Mar 14, 2026 - Major League Soccer

Charlotte FC
0 :  0
Inter Miami
Chicago Fire
Chicago Fire Latest matches
L L L W W W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

3.5 Total goals
83% BTTS
1.83 Goals scored
1.67 Goals conceded
83% Over 2.5
17% Under 2.5

May 23, 2026 - Major League Soccer

Chicago Fire
2 :  1
Toronto FC

May 16, 2026 - Major League Soccer

CF Montreal
0 :  2
Chicago Fire

May 13, 2026 - Major League Soccer

DC United
1 :  3
Chicago Fire

May 9, 2026 - Major League Soccer

Chicago Fire
1 :  3
New York Red Bulls

May 2, 2026 - Major League Soccer

Chicago Fire
2 :  3
FC Cincinnati

Apr 29, 2026 - US Open Cup

Chicago Fire
1 :  2
Saint Louis City SC
W W L L L W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

3.5 Total goals
67% BTTS
2 Goals scored
1.5 Goals conceded
83% Over 2.5
17% Under 2.5

May 23, 2026 - Major League Soccer

Chicago Fire
2 :  1
Toronto FC

May 9, 2026 - Major League Soccer

Chicago Fire
1 :  3
New York Red Bulls

May 2, 2026 - Major League Soccer

Chicago Fire
2 :  3
FC Cincinnati

Apr 29, 2026 - US Open Cup

Chicago Fire
1 :  2
Saint Louis City SC

Apr 25, 2026 - Major League Soccer

Chicago Fire
5 :  0
Sporting Kansas City

Apr 11, 2026 - Major League Soccer

Chicago Fire
1 :  0
Atlanta United Fc
D W W D W W
Victories

4/6 (67%)

Draw

2/6 (33%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

3 Total goals
67% BTTS
2 Goals scored
1 Goals conceded
67% Over 2.5
33% Under 2.5

May 16, 2026 - Major League Soccer

CF Montreal
0 :  2
Chicago Fire

May 13, 2026 - Major League Soccer

DC United
1 :  3
Chicago Fire

Apr 18, 2026 - Major League Soccer

FC Cincinnati
3 :  3
Chicago Fire

Apr 14, 2026 - US Open Cup

Detroit City FC
1 :  2
Chicago Fire

Mar 21, 2026 - Major League Soccer

Philadelphia Union
1 :  2
Chicago Fire

Mar 7, 2026 - Major League Soccer

Columbus Crew
0 :  0
Chicago Fire

Inter Miami against Chicago Fire : Head to Head (H2H)

Inter Miami

33 %

Draw

17 %

Chicago Fire

50 %

Average stats (last H2H results)

4.33
Total goals
83.33%
BTTS
2
Goals scored
2.33
Goals conceded
83.33%
Over 2.5
16.67%
Under 2.5

Sep 30, 2025 - Major League Soccer

Inter Miami
3 :  5
Chicago Fire

Apr 13, 2025 - Major League Soccer

Chicago Fire
0 :  0
Inter Miami

Aug 31, 2024 - Major League Soccer

Chicago Fire
1 :  4
Inter Miami

Jul 20, 2024 - Major League Soccer

Inter Miami
2 :  1
Chicago Fire

Oct 4, 2023 - Major League Soccer

Chicago Fire
4 :  1
Inter Miami

Mar 25, 2023 - Major League Soccer

Inter Miami
2 :  3
Chicago Fire
Inter Miami vs Chicago Fire Picks

Chicago Fire v Inter Miami last Lineups

Inter Miami

Formation : 4 - 3 - 3

97
D. St. Clair
17
I. Fray
2
G. Lujan
16
Micael
3
S. Reguilon
7
R. De Paul
42
Y. Bright
8
T. Segovia
10
L. Messi
9
L. Suarez
19
G. Berterame
7
M. Haile-Selassie
99
H. Cuypers
11
P. Zinckernagel
17
R. Lod
22
M. Pineda
6
A. Saletros
15
A. Gutman
4
M. Mbokazi
3
J. Elliott
24
J. Dean
1
C. Brady

Formation : 4 - 3 - 3

Chicago Fire

Substitutes

Inter Miami
Inter Miami
Goalkeeper

R. Rios Novo

Defender

M. Falcon

N. Allen

F. Mura

Midfielder

P. Plambeck

D. Ruiz

D. Ayala

Forward

D. Pinter

M. Silvetti

Chicago Fire
Chicago Fire
Goalkeeper

J. Cohen

Defender

D. D'avilla

P. Dithejane

J. Waterman

V. Radojevic

Midfielder

D. Borso

S. Oregel

Forward

J. Shokalook

C. Mueller

Missing players

Inter Miami
Inter Miami
Forward

T. Allende

Chicago Fire
Chicago Fire
Defender

L. Barroso

Midfielder

A. Franco

Forward

J. Bamba

Most goals and assists

CD Huachipato Inter Miami
CD Huachipato Chicago Fire
Top Goalscorer
Argentina L. Messi (12 Goals)
Top Goalscorer
Belgium H. Cuypers (13 Goals)
Best assists
Argentina L. Messi (7 Assists)
Best assists
Denmark P. Zinckernagel (7 Assists)

Inter Miami - Chicago Fire Key Points

  1. Chicago Fire have only conceded two goals in their last three matches.
  2. It’s very likely that Inter Miami are missing two crucial offensive players for this game.
  3. The last time Inter Miami faced a top side, the result was a 1-1 tie.
  4. The hosts scored only one goal in their most recent game against a top-ranked side.
  5. The Fire’s fixture against Nashville concluded with just one goal.
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Our Inter Miami vs Chicago Fire Prediction

In addition to those above, two further examples include two goals when the home side met with both Real Salt Lake and New England Revolution this season, as well as failing to score against LAFC. In contrast to facing lesser teams in the league, the trend of similar fixtures shows that the more challenging games, those with more at stake, tend to be more reserved. 

What’s more, we must factor in that it is highly unlikely that two of interim manager Hoyos’ best men, Messi and De Paul, will return from the World Cup for this first game back. The last time both were missing from the squad, the game finished goalless, which is very interesting. 

Our Inter Miami vs Chicago Fire Pick: Under 3.5 Goals.

Prediction:

 

Under 3.5 Goals

+110
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.