Detroit Lions vs Cincinnati Bengals Prediction & Picks - NFL

USA - NFL

Detroit Lions
10/5/25 16:25
Cincinnati Bengals

Prediction:

 

Detroit Lions -9.5 Alternate Spread

-127
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 by Matt Lowrimore in NFL Picks

One of the late games on the Week 5 NFL Sunday slate will see the Cincinnati Bengals take on the Detroit Lions. Let’s take a look at the match statistics and predictions for this game between the Bengals and the Lions.

Detroit enters this game with a record of 3-1, having most recently beaten the Cleveland Browns in Week 4 by a score of 34-10. The Lions’ offense had a total of 277 yards, while its defense allowed 249 yards. Quarterback Jared Goff threw for 168 yards, two touchdowns, and one interception, while running back Jahmyr Gibbs led the team in rushing with 91 yards and one touchdown.

As for Cincinnati, they enter this game with a record of 2-2, having most recently lost to the Denver Broncos in Week 4 by a score of 28-3. The Bengals’ offense had a total of 129 yards, while its defense allowed 512 yards. Quarterback Jake Browning threw for 125 yards, while running back Chase Brown led the team in rushing with 40 yards.

Detroit Lions vs Cincinnati Bengals Form

Table

Teams % P W D L
7
Detroit Lions
Detroit Lions
0.75 4 3 0 1
15
Cincinnati Bengals
Cincinnati Bengals
0.5 4 2 0 2

Detroit Lions and Cincinnati Bengals Latest Matches

Detroit Lions
Detroit Lions Latest matches
W L L W W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Sep 28, 2025 - NFL

Cleveland Browns
10 :  34
Detroit Lions

Sep 22, 2025 - NFL

Detroit Lions
38 :  30
Baltimore Ravens

Sep 14, 2025 - NFL

Chicago Bears
21 :  52
Detroit Lions

Sep 7, 2025 - NFL

Detroit Lions
13 :  27
Green Bay Packers

Jan 18, 2025 - NFL

Washington Commanders
45 :  31
Detroit Lions

Jan 5, 2025 - NFL

Minnesota Vikings
9 :  31
Detroit Lions
W L W L W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Sep 28, 2025 - NFL

Cleveland Browns
10 :  34
Detroit Lions

Sep 14, 2025 - NFL

Chicago Bears
21 :  52
Detroit Lions

Jan 18, 2025 - NFL

Washington Commanders
45 :  31
Detroit Lions

Jan 5, 2025 - NFL

Minnesota Vikings
9 :  31
Detroit Lions

Dec 15, 2024 - NFL

Buffalo Bills
48 :  42
Detroit Lions

Dec 5, 2024 - NFL

Green Bay Packers
31 :  34
Detroit Lions
W W W W L W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Sep 22, 2025 - NFL

Detroit Lions
38 :  30
Baltimore Ravens

Sep 7, 2025 - NFL

Detroit Lions
13 :  27
Green Bay Packers

Dec 30, 2024 - NFL

Detroit Lions
40 :  34
San Francisco 49ers

Dec 22, 2024 - NFL

Detroit Lions
34 :  17
Chicago Bears

Nov 24, 2024 - NFL

Detroit Lions
24 :  6
Indianapolis Colts

Nov 10, 2024 - NFL

Detroit Lions
26 :  23
Houston Texans
Cincinnati Bengals
Cincinnati Bengals Latest matches
W W W W L L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Sep 29, 2025 - NFL

Cincinnati Bengals
3 :  28
Denver Broncos

Sep 21, 2025 - NFL

Cincinnati Bengals
10 :  48
Minnesota Vikings

Sep 14, 2025 - NFL

Jacksonville Jaguars
27 :  31
Cincinnati Bengals

Sep 7, 2025 - NFL

Cincinnati Bengals
17 :  16
Cleveland Browns

Jan 4, 2025 - NFL

Cincinnati Bengals
19 :  17
Pittsburgh Steelers

Dec 28, 2024 - NFL

Denver Broncos
24 :  30
Cincinnati Bengals
L W L W W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Sep 14, 2025 - NFL

Jacksonville Jaguars
27 :  31
Cincinnati Bengals

Dec 28, 2024 - NFL

Denver Broncos
24 :  30
Cincinnati Bengals

Dec 22, 2024 - NFL

Cleveland Browns
6 :  24
Cincinnati Bengals

Dec 1, 2024 - NFL

Pittsburgh Steelers
44 :  38
Cincinnati Bengals

Nov 3, 2024 - NFL

Las Vegas Raiders
24 :  41
Cincinnati Bengals

Oct 27, 2024 - NFL

Philadelphia Eagles
37 :  17
Cincinnati Bengals
W W W W L L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Sep 29, 2025 - NFL

Cincinnati Bengals
3 :  28
Denver Broncos

Sep 21, 2025 - NFL

Cincinnati Bengals
10 :  48
Minnesota Vikings

Sep 7, 2025 - NFL

Cincinnati Bengals
17 :  16
Cleveland Browns

Jan 4, 2025 - NFL

Cincinnati Bengals
19 :  17
Pittsburgh Steelers

Dec 15, 2024 - NFL

Cincinnati Bengals
37 :  27
Tennessee Titans

Dec 9, 2024 - NFL

Cincinnati Bengals
27 :  20
Dallas Cowboys

Detroit Lions - Cincinnati Bengals Key Points

  1. The Bengals are 1-3 ATS this season
  2. The Lions are 3-1 ATS this season
  3. The Bengals are averaging 15.3 points per game this season
  4. The Lions are averaging 34.3 points per game this season

Our Detroit Lions vs Cincinnati Bengals Prediction

Since the Bengals lost quarterback Joe Burrow to injury, they have simply been awful. In the last two games that Jake Browning has started, Cincinnati is averaging 6.5 points per game. 

As for Detroit, they have looked like one of the best teams in the league following their loss in Week 1. Since the loss to the Green Bay Packers in Week 1, the Lions’ offense has averaged 41.3 points per game.

The Lions have a potent rushing attack, and their passing offense can also be explosive at any time. Therefore, given the lack of ability the Bengals have shown over the last two weeks, our Cincinnati Bengals vs Detroit Lions prediction is: Detroit Lions -9.5 Alternate Spread.

Prediction:

 

Detroit Lions -9.5 Alternate Spread

-127
$200 offered for betting!

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Detroit Lions vs Cincinnati Bengals Picks