Seattle Seahawks vs Tampa Bay Buccaneers Prediction & Picks - NFL

USA - NFL

Seattle Seahawks
10/5/25 16:05
Tampa Bay Buccaneers

Prediction:

 

Over 45.5

-106
$350 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Erik Gibbs | in NFL Picks

The Tampa Bay Buccaneers and Seattle Seahawks meet Sunday at Lumen Field in a pivotal NFC showdown between two first-place teams. Both enter the week at 3-1, making this one of the most important early-season matchups in the conference. Tampa Bay is coming off a 31-25 loss to the Philadelphia Eagles, a game where their offense disappeared in the second half. The Buccaneers still hold first place in the NFC South, but they’ll face major challenges on offense this week. With Irving and Evans both ruled out, quarterback Baker Mayfield will be forced to shoulder more of the workload against one of the league’s best defensive units.

Seattle enters this game riding the momentum of a 23-20 win over Arizona. The Seahawks currently lead the NFC West and have been one of the most balanced teams in the league so far. Offensively, they rank sixth in scoring at 27.8 points per game, and defensively, they’re second in the NFL, giving up just 16.8 points per contest. That balance has been the key to their early success, with the team showing an ability to both control the clock and limit explosive plays.

Seattle Seahawks vs Tampa Bay Buccaneers Form

Table

Teams Pts P W L
1 Seattle Seahawks
0.824 17 14 3
16 Tampa Bay Buccaneers
0.471 17 8 9

Seattle Seahawks and Tampa Bay Buccaneers Latest Matches

Seattle Seahawks
Seattle Seahawks Latest matches
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 25, 2025 - NFL

Arizona Cardinals
20 :  23
Seattle Seahawks

Sep 21, 2025 - NFL

Seattle Seahawks
44 :  13
New Orleans Saints

Sep 14, 2025 - NFL

Pittsburgh Steelers
17 :  31
Seattle Seahawks

Sep 7, 2025 - NFL

Seattle Seahawks
13 :  17
San Francisco 49ers

Jan 5, 2025 - NFL

Los Angeles Rams
25 :  30
Seattle Seahawks

Dec 26, 2024 - NFL

Chicago Bears
3 :  6
Seattle Seahawks
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 21, 2025 - NFL

Seattle Seahawks
44 :  13
New Orleans Saints

Sep 7, 2025 - NFL

Seattle Seahawks
13 :  17
San Francisco 49ers

Dec 22, 2024 - NFL

Seattle Seahawks
24 :  27
Minnesota Vikings

Dec 15, 2024 - NFL

Seattle Seahawks
13 :  30
Green Bay Packers

Nov 24, 2024 - NFL

Seattle Seahawks
16 :  6
Arizona Cardinals

Nov 3, 2024 - NFL

Seattle Seahawks
20 :  26
Los Angeles Rams
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Sep 25, 2025 - NFL

Arizona Cardinals
20 :  23
Seattle Seahawks

Sep 14, 2025 - NFL

Pittsburgh Steelers
17 :  31
Seattle Seahawks

Jan 5, 2025 - NFL

Los Angeles Rams
25 :  30
Seattle Seahawks

Dec 26, 2024 - NFL

Chicago Bears
3 :  6
Seattle Seahawks

Dec 8, 2024 - NFL

Arizona Cardinals
18 :  30
Seattle Seahawks

Dec 1, 2024 - NFL

New York Jets
21 :  26
Seattle Seahawks
Tampa Bay Buccaneers
Tampa Bay Buccaneers Latest matches
W L W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 28, 2025 - NFL

Tampa Bay Buccaneers
25 :  31
Philadelphia Eagles

Sep 21, 2025 - NFL

Tampa Bay Buccaneers
29 :  27
New York Jets

Sep 15, 2025 - NFL

Houston Texans
19 :  20
Tampa Bay Buccaneers

Sep 7, 2025 - NFL

Atlanta Falcons
20 :  23
Tampa Bay Buccaneers

Jan 12, 2025 - NFL

Tampa Bay Buccaneers
20 :  23
Washington Commanders

Jan 5, 2025 - NFL

Tampa Bay Buccaneers
27 :  19
New Orleans Saints
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 28, 2025 - NFL

Tampa Bay Buccaneers
25 :  31
Philadelphia Eagles

Sep 21, 2025 - NFL

Tampa Bay Buccaneers
29 :  27
New York Jets

Jan 12, 2025 - NFL

Tampa Bay Buccaneers
20 :  23
Washington Commanders

Jan 5, 2025 - NFL

Tampa Bay Buccaneers
27 :  19
New Orleans Saints

Dec 29, 2024 - NFL

Tampa Bay Buccaneers
48 :  14
Carolina Panthers

Dec 8, 2024 - NFL

Tampa Bay Buccaneers
28 :  13
Las Vegas Raiders
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 15, 2025 - NFL

Houston Texans
19 :  20
Tampa Bay Buccaneers

Sep 7, 2025 - NFL

Atlanta Falcons
20 :  23
Tampa Bay Buccaneers

Dec 22, 2024 - NFL

Dallas Cowboys
26 :  24
Tampa Bay Buccaneers

Dec 15, 2024 - NFL

Los Angeles Chargers
17 :  40
Tampa Bay Buccaneers

Nov 24, 2024 - NFL

New York Giants
7 :  30
Tampa Bay Buccaneers

Nov 4, 2024 - NFL

Kansas City Chiefs
30 :  24
Tampa Bay Buccaneers

Seattle Seahawks - Tampa Bay Buccaneers Key Points

  1. The Over is 11-1 in the Seahawks’ last 12 home games vs. NFC South teams
  2. The Over is 1-9 in the Buccaneers’ last 10 road games after a home loss
  3. The Buccaneers are 1-10 in their last 11 games vs. teams on a winning streak
  4. The Buccaneers are 0-4 ATS in their last 4 Week 5 games vs. NFC teams

Our Seattle Seahawks vs Tampa Bay Buccaneers Prediction

This matchup will likely hinge on whether Tampa Bay can find rhythm through the air. Mayfield will need to rely on quick passes and his secondary receivers to keep drives alive, as Seattle’s front seven has been tough on both the run and intermediate passing lanes. The Buccaneers’ defense has been inconsistent, and if they can’t generate pressure or tighten coverage, Seattle should be able to move the ball effectively.

Historically, Tampa Bay has had some success in this series, winning five of the last seven meetings, including a 21-16 victory in 2022. However, the Seahawks have dominated at home, going 3-1 in their last four in Seattle and outscoring opponents by an average of 11 points per game this season. With home-field advantage, better health, and stronger overall balance, Seattle is the clear favorite to take control early and stay ahead. Our prediction for Seattle Seahawks vs. Tampa Bay Buccaneers: Over 45.5 points.

Prediction:

 

Over 45.5

-106
$350 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Seattle Seahawks vs Tampa Bay Buccaneers Picks