Atlanta Falcons vs Arizona Cardinals Prediction & Picks - NFL

USA - NFL

Atlanta Falcons
12/21/25 16:05
Arizona Cardinals

Prediction:

 

The Falcons -2.5 points

-120
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 by Lou Aguila in NFL Picks

The Atlanta Falcons are -156 moneyline favorites ahead of their clash with the Arizona Cardinals on Sunday at State Farm Stadium.

Current Form:

The Falcons have won two of their last four games, improving their record to 5-9. Atlanta may no longer be in contention for the postseason. Still, it managed to salvage a morale-boosting victory over the Tampa Bay Buccaneers, 29-28, last week, avenging their narrow 20-23 loss to the same team in the first week of the season. Atlanta has put up mediocre numbers this season, ranking 26th in the NFL in points per game (20.1) and 22nd in points allowed per game (24.4).

Meanwhile, the Cardinals will try to end a six-game losing streak on Sunday. Arizona’s last win came at the expense of the Dallas Cowboys, 27-17, in Week 9. Since then, Arizona’s defense has struggled to contain teams, as 4 out of these 6 opponents have scored at least 40 points. The Cards are the worst team in the top-heavy NFC West with a 3-11 record.

Atlanta Falcons vs Arizona Cardinals Form

Table

Teams % P W D L
23
Atlanta Falcons
Atlanta Falcons
0.357 14 5 0 9
27
Arizona Cardinals
Arizona Cardinals
0.214 14 3 0 11

Atlanta Falcons and Arizona Cardinals Latest Matches

Atlanta Falcons
Atlanta Falcons Latest matches
L L W L L W
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Dec 11, 2025 - NFL

Atlanta Falcons
29 :  28
Tampa Bay Buccaneers

Dec 7, 2025 - NFL

Seattle Seahawks
37 :  9
Atlanta Falcons

Nov 30, 2025 - NFL

Atlanta Falcons
24 :  27
New York Jets

Nov 23, 2025 - NFL

Atlanta Falcons
24 :  10
New Orleans Saints

Nov 16, 2025 - NFL

Carolina Panthers
30 :  27
Atlanta Falcons

Nov 9, 2025 - NFL

Atlanta Falcons
25 :  31
Indianapolis Colts
L W W L L L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Dec 7, 2025 - NFL

Seattle Seahawks
37 :  9
Atlanta Falcons

Nov 16, 2025 - NFL

Carolina Panthers
30 :  27
Atlanta Falcons

Oct 26, 2025 - NFL

Miami Dolphins
34 :  10
Atlanta Falcons

Oct 13, 2025 - NFL

Buffalo Bills
14 :  24
Atlanta Falcons

Sep 28, 2025 - NFL

Washington Commanders
27 :  34
Atlanta Falcons

Sep 7, 2025 - NFL

Tampa Bay Buccaneers
23 :  20
Atlanta Falcons
L L L W L W
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Dec 11, 2025 - NFL

Atlanta Falcons
29 :  28
Tampa Bay Buccaneers

Nov 30, 2025 - NFL

Atlanta Falcons
24 :  27
New York Jets

Nov 23, 2025 - NFL

Atlanta Falcons
24 :  10
New Orleans Saints

Nov 9, 2025 - NFL

Atlanta Falcons
25 :  31
Indianapolis Colts

Nov 2, 2025 - NFL

Atlanta Falcons
23 :  24
New England Patriots

Oct 19, 2025 - NFL

Atlanta Falcons
10 :  20
San Francisco 49ers
Arizona Cardinals
Arizona Cardinals Latest matches
L L L L L L
Victories

0/6 (0%)

Draw

0/6 (0%)

Defeats

6/6 (100%)

Dec 14, 2025 - NFL

Arizona Cardinals
20 :  40
Houston Texans

Dec 7, 2025 - NFL

Los Angeles Rams
45 :  17
Arizona Cardinals

Nov 30, 2025 - NFL

Arizona Cardinals
17 :  20
Tampa Bay Buccaneers

Nov 23, 2025 - NFL

Jacksonville Jaguars
27 :  24
Arizona Cardinals

Nov 16, 2025 - NFL

San Francisco 49ers
41 :  22
Arizona Cardinals

Nov 9, 2025 - NFL

Arizona Cardinals
22 :  44
Seattle Seahawks
L L L L L L
Victories

0/6 (0%)

Draw

0/6 (0%)

Defeats

6/6 (100%)

Dec 7, 2025 - NFL

Los Angeles Rams
45 :  17
Arizona Cardinals

Nov 23, 2025 - NFL

Jacksonville Jaguars
27 :  24
Arizona Cardinals

Nov 16, 2025 - NFL

San Francisco 49ers
41 :  22
Arizona Cardinals

Oct 19, 2025 - NFL

Green Bay Packers
27 :  23
Arizona Cardinals

Oct 5, 2025 - NFL

Tennessee Titans
22 :  21
Arizona Cardinals

Sep 25, 2025 - NFL

Seattle Seahawks
23 :  20
Arizona Cardinals
L L W L L L
Victories

1/6 (17%)

Draw

0/6 (0%)

Defeats

5/6 (83%)

Dec 14, 2025 - NFL

Arizona Cardinals
20 :  40
Houston Texans

Nov 30, 2025 - NFL

Arizona Cardinals
17 :  20
Tampa Bay Buccaneers

Nov 9, 2025 - NFL

Arizona Cardinals
22 :  44
Seattle Seahawks

Nov 3, 2025 - NFL

Arizona Cardinals
27 :  17
Dallas Cowboys

Oct 12, 2025 - NFL

Arizona Cardinals
27 :  31
Indianapolis Colts

Sep 21, 2025 - NFL

Arizona Cardinals
15 :  16
San Francisco 49ers

Atlanta Falcons against Arizona Cardinals : Head to Head (H2H)

Nov 12, 2023 - NFL

Atlanta Falcons
23 :  25
Arizona Cardinals

Atlanta Falcons - Arizona Cardinals Key Points

  1. Arizona is 0-6 SU in its last 6 games.
  2. Arizona is 1-7 SU in its last 8 games against an opponent in the National Football Conference
  3. Atlanta is 2-7 SU in its last 9 games.
  4. Atlanta is 10-5 SU in its last 15 games against Arizona.

Our Atlanta Falcons vs Arizona Cardinals Prediction

Fearless Forecast: I am picking the Falcons to win and cover -2.5 points against the Cardinals. The Cardinals are 5-0 SU in their last 5 home games against Atlanta, but in their last 6 games, they have struggled to stop opposing teams from scoring at an alarming rate. Arizona is averaging 27.7 points allowed per game this season, but these numbers don’t reflect the current dreadful state of the Cards’ defense, which surrendered at least 40 points in 4 of their last 5 games. The Falcons are not a good offensive team either, as they average only 20.1 points per game this season (26th in the NFL). Still, I believe Atlanta has a better chance of scoring more than 30 points than Arizona holding its opponent under 40.

Our betting prediction for the Atlanta Falcons vs. the Arizona Cardinals: The Falcons will cover -2.5 points

Prediction:

 

The Falcons -2.5 points

-120
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Atlanta Falcons vs Arizona Cardinals Picks