Detroit Lions vs Pittsburgh Steelers Prediction & Picks - NFL

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Detroit Lions
12/21/25 16:25
Pittsburgh Steelers

Prediction:

 

Pittsburgh Steelers +7.5 Alternate Spread

-133
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 by Matt Lowrimore | in NFL Picks

One of the better Week 16 games in the NFL will see the Pittsburgh Steelers take on the Detroit Lions. Let’s take a look at the match statistics and predictions for this game between the Lions and the Steelers.

Pittsburgh enters this game with a record of 8-6, having most recently beaten the Miami Dolphins in Week 15 by a score of 28-15. The Steelers’ offense had a total of 336 yards, while its defense allowed 285 yards. Quarterback Aaron Rodgers threw for 224 yards and two touchdowns, while running back Kenneth Gainwell led the team in rushing with 80 yards.

As for Detroit, they enter this game with a record of 8-6, having most recently lost to the Los Angeles Rams in Week 15 by a score of 41-34. The Lions’ offense had a total of 396 yards, while its defense allowed 519 yards. Quarterback Jared Goff threw for 338 yards and three touchdowns, while running back Jahmyr Gibbs led the team in rushing with 38 yards.

Detroit Lions vs Pittsburgh Steelers Form

Table

Teams Pts P W L
12 Pittsburgh Steelers
0.588 17 10 7
15 Detroit Lions
0.529 17 9 8

Detroit Lions and Pittsburgh Steelers Latest Matches

Detroit Lions
Detroit Lions Latest matches
W L W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Dec 14, 2025 - NFL

Los Angeles Rams
41 :  34
Detroit Lions

Dec 4, 2025 - NFL

Detroit Lions
44 :  30
Dallas Cowboys

Nov 27, 2025 - NFL

Detroit Lions
24 :  31
Green Bay Packers

Nov 23, 2025 - NFL

Detroit Lions
34 :  27
New York Giants

Nov 16, 2025 - NFL

Philadelphia Eagles
16 :  9
Detroit Lions

Nov 9, 2025 - NFL

Washington Commanders
22 :  44
Detroit Lions
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Dec 4, 2025 - NFL

Detroit Lions
44 :  30
Dallas Cowboys

Nov 27, 2025 - NFL

Detroit Lions
24 :  31
Green Bay Packers

Nov 23, 2025 - NFL

Detroit Lions
34 :  27
New York Giants

Nov 2, 2025 - NFL

Detroit Lions
24 :  27
Minnesota Vikings

Oct 20, 2025 - NFL

Detroit Lions
24 :  9
Tampa Bay Buccaneers

Sep 28, 2025 - NFL

Detroit Lions
34 :  10
Cleveland Browns
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Dec 14, 2025 - NFL

Los Angeles Rams
41 :  34
Detroit Lions

Nov 16, 2025 - NFL

Philadelphia Eagles
16 :  9
Detroit Lions

Nov 9, 2025 - NFL

Washington Commanders
22 :  44
Detroit Lions

Oct 12, 2025 - NFL

Kansas City Chiefs
30 :  17
Detroit Lions

Oct 5, 2025 - NFL

Cincinnati Bengals
24 :  37
Detroit Lions

Sep 22, 2025 - NFL

Baltimore Ravens
30 :  38
Detroit Lions
Pittsburgh Steelers
Pittsburgh Steelers Latest matches
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Dec 15, 2025 - NFL

Pittsburgh Steelers
28 :  15
Miami Dolphins

Dec 7, 2025 - NFL

Baltimore Ravens
22 :  27
Pittsburgh Steelers

Nov 30, 2025 - NFL

Pittsburgh Steelers
7 :  26
Buffalo Bills

Nov 23, 2025 - NFL

Chicago Bears
31 :  28
Pittsburgh Steelers

Nov 16, 2025 - NFL

Pittsburgh Steelers
34 :  12
Cincinnati Bengals

Nov 9, 2025 - NFL

Los Angeles Chargers
25 :  10
Pittsburgh Steelers
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Dec 15, 2025 - NFL

Pittsburgh Steelers
28 :  15
Miami Dolphins

Nov 30, 2025 - NFL

Pittsburgh Steelers
7 :  26
Buffalo Bills

Nov 16, 2025 - NFL

Pittsburgh Steelers
34 :  12
Cincinnati Bengals

Nov 2, 2025 - NFL

Pittsburgh Steelers
27 :  20
Indianapolis Colts

Oct 26, 2025 - NFL

Pittsburgh Steelers
25 :  35
Green Bay Packers

Oct 12, 2025 - NFL

Pittsburgh Steelers
23 :  9
Cleveland Browns
W W L L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Dec 7, 2025 - NFL

Baltimore Ravens
22 :  27
Pittsburgh Steelers

Nov 23, 2025 - NFL

Chicago Bears
31 :  28
Pittsburgh Steelers

Nov 9, 2025 - NFL

Los Angeles Chargers
25 :  10
Pittsburgh Steelers

Oct 16, 2025 - NFL

Cincinnati Bengals
33 :  31
Pittsburgh Steelers

Sep 21, 2025 - NFL

New England Patriots
14 :  21
Pittsburgh Steelers

Sep 7, 2025 - NFL

New York Jets
32 :  34
Pittsburgh Steelers

Detroit Lions against Pittsburgh Steelers : Head to Head (H2H)

Detroit Lions

100 %

Pittsburgh Steelers

0 %

Nov 14, 2021 - NFL

Pittsburgh Steelers
16 :  16
Detroit Lions

Detroit Lions - Pittsburgh Steelers Key Points

  1. Pittsburgh is 3-3 SU on the road
  2. Pittsburgh is 2-0 SU in their last two games
  3. Detroit is 5-2 SU at home
  4. Detroit is 2-3 SU in their last five games

Our Detroit Lions vs Pittsburgh Steelers Prediction

The Lions are about a touchdown favorite in this matchup; however, the Steelers look to be the best betting option. Detroit is in danger of missing the playoffs as they have a mediocre record. Their offense has been excellent at times this season, but their defense has also allowed a ton of points over the last few weeks.

The Steelers, on the other hand, are fighting for the AFC North division, which they lead by one game as it stands. Pittsburgh has also won back-to-back games and has been improving every week. 

As good as the Lions’ offense has been, their defense has let them down on numerous occasions. Because of that, our Detroit Lions vs Pittsburgh Steelers prediction is: Pittsburgh Steelers +7.5 Alternate Spread.

Prediction:

 

Pittsburgh Steelers +7.5 Alternate Spread

-133
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Detroit Lions vs Pittsburgh Steelers Picks