Carolina Panthers vs Tampa Bay Buccaneers Prediction & Picks - NFL

USA - NFL

Carolina Panthers
12/21/25 13:00
Tampa Bay Buccaneers

Prediction:

 

The Panthers will win

+124
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 by Lou Aguila | in NFL Picks

The Tampa Bay Buccaneers are -146 road favorites ahead of their crucial battle with the Carolina Panthers on Sunday at Bank of America Stadium.

Current Form:

The Buccaneers have now lost five of their last six games following last week’s loss to the Atlanta Falcons, 28-29. As a result, Tampa Bay finds itself in a dogfight with Carolina for the NFC South title. Baker Mayfield passed for 277 yards with two touchdowns and one interception against Atlanta, but again, the Buccaneers’ defense failed to hold a 14-point lead in the fourth quarter. Tampa Bay ranks 24th in the NFL in points allowed per game (25.3).

The Panthers lost their last game to the New Orleans Saints, 20-17, but at least they have won 2 of their last 5 games to remain in the division title race. Quarterback Bryce Young passed for 163 yards with one TD and running back Rico Dowdle ran for 49 yards on 16 carries with one TD in a losing effort. Carolina is the 14th-best defensive team in the NFL, allowing opponents to average 22.6 points per game.

Carolina Panthers vs Tampa Bay Buccaneers Form

Table

Teams Pts P W L
16 Tampa Bay Buccaneers
0.471 17 8 9
18 Carolina Panthers
0.471 17 8 9

Carolina Panthers and Tampa Bay Buccaneers Latest Matches

Carolina Panthers
Carolina Panthers Latest matches
W L W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Dec 14, 2025 - NFL

New Orleans Saints
20 :  17
Carolina Panthers

Nov 30, 2025 - NFL

Carolina Panthers
31 :  28
Los Angeles Rams

Nov 24, 2025 - NFL

San Francisco 49ers
20 :  9
Carolina Panthers

Nov 16, 2025 - NFL

Atlanta Falcons
27 :  30
Carolina Panthers

Nov 9, 2025 - NFL

Carolina Panthers
7 :  17
New Orleans Saints

Nov 2, 2025 - NFL

Green Bay Packers
13 :  16
Carolina Panthers
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 30, 2025 - NFL

Carolina Panthers
31 :  28
Los Angeles Rams

Nov 9, 2025 - NFL

Carolina Panthers
7 :  17
New Orleans Saints

Oct 26, 2025 - NFL

Carolina Panthers
9 :  40
Buffalo Bills

Oct 12, 2025 - NFL

Carolina Panthers
30 :  27
Dallas Cowboys

Oct 5, 2025 - NFL

Carolina Panthers
27 :  24
Miami Dolphins

Sep 21, 2025 - NFL

Carolina Panthers
30 :  0
Atlanta Falcons
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Dec 14, 2025 - NFL

New Orleans Saints
20 :  17
Carolina Panthers

Nov 24, 2025 - NFL

San Francisco 49ers
20 :  9
Carolina Panthers

Nov 16, 2025 - NFL

Atlanta Falcons
27 :  30
Carolina Panthers

Nov 2, 2025 - NFL

Green Bay Packers
13 :  16
Carolina Panthers

Oct 19, 2025 - NFL

New York Jets
6 :  13
Carolina Panthers

Sep 28, 2025 - NFL

New England Patriots
42 :  13
Carolina Panthers
Tampa Bay Buccaneers
Tampa Bay Buccaneers Latest matches
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Dec 11, 2025 - NFL

Tampa Bay Buccaneers
28 :  29
Atlanta Falcons

Dec 7, 2025 - NFL

Tampa Bay Buccaneers
20 :  24
New Orleans Saints

Nov 30, 2025 - NFL

Tampa Bay Buccaneers
20 :  17
Arizona Cardinals

Nov 23, 2025 - NFL

Los Angeles Rams
34 :  7
Tampa Bay Buccaneers

Nov 16, 2025 - NFL

Buffalo Bills
44 :  32
Tampa Bay Buccaneers

Nov 9, 2025 - NFL

Tampa Bay Buccaneers
23 :  28
New England Patriots
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Dec 11, 2025 - NFL

Tampa Bay Buccaneers
28 :  29
Atlanta Falcons

Dec 7, 2025 - NFL

Tampa Bay Buccaneers
20 :  24
New Orleans Saints

Nov 30, 2025 - NFL

Tampa Bay Buccaneers
20 :  17
Arizona Cardinals

Nov 9, 2025 - NFL

Tampa Bay Buccaneers
23 :  28
New England Patriots

Oct 12, 2025 - NFL

Tampa Bay Buccaneers
30 :  19
San Francisco 49ers

Sep 28, 2025 - NFL

Tampa Bay Buccaneers
25 :  31
Philadelphia Eagles
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 23, 2025 - NFL

Los Angeles Rams
34 :  7
Tampa Bay Buccaneers

Nov 16, 2025 - NFL

Buffalo Bills
44 :  32
Tampa Bay Buccaneers

Oct 26, 2025 - NFL

New Orleans Saints
3 :  23
Tampa Bay Buccaneers

Oct 20, 2025 - NFL

Detroit Lions
24 :  9
Tampa Bay Buccaneers

Oct 5, 2025 - NFL

Seattle Seahawks
35 :  38
Tampa Bay Buccaneers

Sep 15, 2025 - NFL

Houston Texans
19 :  20
Tampa Bay Buccaneers

Carolina Panthers against Tampa Bay Buccaneers : Head to Head (H2H)

Carolina Panthers

0 %

Tampa Bay Buccaneers

100 %

Dec 29, 2024 - NFL

Tampa Bay Buccaneers
48 :  14
Carolina Panthers

Jan 7, 2024 - NFL

Carolina Panthers
0 :  9
Tampa Bay Buccaneers

Dec 3, 2023 - NFL

Tampa Bay Buccaneers
21 :  18
Carolina Panthers

Carolina Panthers - Tampa Bay Buccaneers Key Points

  1. Carolina is 1-5 SU in its last 6 games when playing at home against Tampa Bay.
  2. Carolina is 12-5 ATS in its last 17 games against an opponent in the National Football Conference conference.
  3. Tampa Bay is 1-5 SU in its last 6 games.
  4. Tampa Bay is 1-4 SU in its last 5 games.

Our Carolina Panthers vs Tampa Bay Buccaneers Prediction

Forecast: Carolina is 1-5 SU in its last 6 games when playing at home against Tampa Bay, while Tampa Bay is 1-5 SU in its last 6 games. This is a tricky game to pick a winner, but I am leaning toward the home team to pull off the win. Carolina is 4-2 on their turf this season. The Buccaneers would not allow their postseason streak to end, but their defence hasn’t performed well in their last six games. Meanwhile, the Panthers showed they can take down elite-level squads when everything is going their way, as they shocked the LA Rams, 31-28, two weeks ago.

Our betting prediction for the Tampa Bay Buccaneers vs. the Carolina Panthers: The Panthers will win.

Prediction:

 

The Panthers will win

+124
$350 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Carolina Panthers vs Tampa Bay Buccaneers Picks