Seattle Seahawks vs Arizona Cardinals Prediction & Picks - NFL

USA - NFL

Seattle Seahawks
11/8/26 16:25
Arizona Cardinals

Prediction:

 

Over 39.5 points

−110
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 by Carlos Zabala | in NFL Picks

The reigning NFL champions, the Seahawks, have started their new season with a 4-4 record, surpassing all the losses they suffered during their championship run. Even so, the Seahawks, led by quarterback Drew Lock, who will replace the injured Sam Darnold, are -400 favorites to defeat the Cardinals at Lume Field.

The Seahawks are coming off a 34-17 home loss to the Bears; that was the game in which Darnold suffered a rib injury late in the game. His replacement, Drew Lock, is also dealing with an elbow injury, so even the third-string quarterback is being trained for the upcoming game. The offensive line is also dealing with some injuries.

The Cardinals are coming off a thrilling 33-30 road win in Dallas against the Cowboys at AT&T Stadium, a game in which they were listed as 7.5-point underdogs by the sportsbooks. They won in overtime in a game where Gardner Minshew completed 17 of 23 passes.

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Seattle Seahawks vs Arizona Cardinals Form

Table

Teams Pts P W L
15 Seattle Seahawks
0.5 8 4 4
22 Arizona Cardinals
0.375 8 3 5

Seattle Seahawks and Arizona Cardinals Latest Matches

Seattle Seahawks
Seattle Seahawks Latest matches
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 2, 2026 - NFL

Seattle Seahawks
17 :  34
Chicago Bears

Oct 25, 2026 - NFL

Seattle Seahawks
20 :  3
Kansas City Chiefs

Oct 15, 2026 - NFL

Denver Broncos
17 :  14
Seattle Seahawks

Oct 11, 2026 - NFL

Seattle Seahawks
29 :  32
San Francisco 49ers

Oct 4, 2026 - NFL

Seattle Seahawks
30 :  23
Los Angeles Chargers

Sep 27, 2026 - NFL

Washington Commanders
33 :  31
Seattle Seahawks
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 2, 2026 - NFL

Seattle Seahawks
17 :  34
Chicago Bears

Oct 25, 2026 - NFL

Seattle Seahawks
20 :  3
Kansas City Chiefs

Oct 11, 2026 - NFL

Seattle Seahawks
29 :  32
San Francisco 49ers

Oct 4, 2026 - NFL

Seattle Seahawks
30 :  23
Los Angeles Chargers

Sep 9, 2026 - NFL

Seattle Seahawks
13 :  10
New England Patriots

Jan 25, 2026 - NFL

Seattle Seahawks
31 :  27
Los Angeles Rams
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Oct 15, 2026 - NFL

Denver Broncos
17 :  14
Seattle Seahawks

Sep 27, 2026 - NFL

Washington Commanders
33 :  31
Seattle Seahawks

Sep 20, 2026 - NFL

Arizona Cardinals
7 :  31
Seattle Seahawks

Feb 8, 2026 - NFL

New England Patriots
13 :  29
Seattle Seahawks

Jan 3, 2026 - NFL

San Francisco 49ers
3 :  13
Seattle Seahawks

Dec 28, 2025 - NFL

Carolina Panthers
10 :  27
Seattle Seahawks
Arizona Cardinals
Arizona Cardinals Latest matches
L L L W L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 1, 2026 - NFL

Dallas Cowboys
30 :  33
Arizona Cardinals

Oct 25, 2026 - NFL

Arizona Cardinals
16 :  30
Denver Broncos

Oct 18, 2026 - NFL

Los Angeles Rams
16 :  18
Arizona Cardinals

Oct 11, 2026 - NFL

Arizona Cardinals
21 :  45
Detroit Lions

Oct 4, 2026 - NFL

New York Giants
36 :  24
Arizona Cardinals

Sep 27, 2026 - NFL

San Francisco 49ers
36 :  30
Arizona Cardinals
L L L L L L
Victories

0/6 (0%)

Defeats

6/6 (100%)

Oct 25, 2026 - NFL

Arizona Cardinals
16 :  30
Denver Broncos

Oct 11, 2026 - NFL

Arizona Cardinals
21 :  45
Detroit Lions

Sep 20, 2026 - NFL

Arizona Cardinals
7 :  31
Seattle Seahawks

Dec 21, 2025 - NFL

Arizona Cardinals
19 :  26
Atlanta Falcons

Dec 7, 2025 - NFL

Arizona Cardinals
17 :  45
Los Angeles Rams

Nov 23, 2025 - NFL

Arizona Cardinals
24 :  27
Jacksonville Jaguars
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 1, 2026 - NFL

Dallas Cowboys
30 :  33
Arizona Cardinals

Oct 18, 2026 - NFL

Los Angeles Rams
16 :  18
Arizona Cardinals

Oct 4, 2026 - NFL

New York Giants
36 :  24
Arizona Cardinals

Sep 27, 2026 - NFL

San Francisco 49ers
36 :  30
Arizona Cardinals

Sep 13, 2026 - NFL

Los Angeles Chargers
14 :  26
Arizona Cardinals

Jan 4, 2026 - NFL

Los Angeles Rams
37 :  20
Arizona Cardinals

Seattle Seahawks against Arizona Cardinals : Head to Head (H2H)

Seattle Seahawks

100 %

Arizona Cardinals

0 %

Sep 20, 2026 - NFL

Arizona Cardinals
7 :  31
Seattle Seahawks

Nov 9, 2025 - NFL

Seattle Seahawks
44 :  22
Arizona Cardinals

Sep 25, 2025 - NFL

Arizona Cardinals
20 :  23
Seattle Seahawks

Dec 8, 2024 - NFL

Arizona Cardinals
18 :  30
Seattle Seahawks

Nov 24, 2024 - NFL

Seattle Seahawks
16 :  6
Arizona Cardinals

Jan 7, 2024 - NFL

Arizona Cardinals
20 :  21
Seattle Seahawks
Seattle Seahawks vs Arizona Cardinals Picks

Seattle Seahawks - Arizona Cardinals Key Points

  1. The Seahawks have won their last 10 games against the Cardinals since 2022
  2. The Seahawks lead the NFL in points per game this season with 236.1
  3. The Seahawks' defense has the third-best 3-down percentage in the NFL
  4. The Cardinals' defense is the worst in the NFL, allowing 29.8 points per game

Our Seattle Seahawks vs Arizona Cardinals Prediction

The Cardinals will also be without their first-choice quarterback; Minshew will get the chance to start after his epic performance against the Cowboys, where he completed 17 passes for 188 yards in just two quarters.

In 3 of the Cardinals' 5 games this season, they have exceeded the total over bet, and last year, when Seattle hosted Arizona, they produced a 66-point game; aiming for a high-scoring game looks like the best option.

Our prediction for Seahawks vs Cardinals is: Over 39.5.

Prediction:

 

Over 39.5 points

−110
$200 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.