Tampa Bay Buccaneers vs Carolina Panthers Prediction & Picks - NFL

USA - NFL

Tampa Bay Buccaneers
12/21/25 13:00
Carolina Panthers

Prediction:

 

The Panthers will win

+124
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 by Lou Aguila in NFL Picks

The Tampa Bay Buccaneers are -146 road favorites ahead of their crucial battle with the Carolina Panthers on Sunday at Bank of America Stadium.

Current Form:

The Buccaneers have now lost five of their last six games following last week’s loss to the Atlanta Falcons, 28-29. As a result, Tampa Bay finds itself in a dogfight with Carolina for the NFC South title. Baker Mayfield passed for 277 yards with two touchdowns and one interception against Atlanta, but again, the Buccaneers’ defense failed to hold a 14-point lead in the fourth quarter. Tampa Bay ranks 24th in the NFL in points allowed per game (25.3).

The Panthers lost their last game to the New Orleans Saints, 20-17, but at least they have won 2 of their last 5 games to remain in the division title race. Quarterback Bryce Young passed for 163 yards with one TD and running back Rico Dowdle ran for 49 yards on 16 carries with one TD in a losing effort. Carolina is the 14th-best defensive team in the NFL, allowing opponents to average 22.6 points per game.

Tampa Bay Buccaneers vs Carolina Panthers Form

Table

Teams % P W D L
16
Carolina Panthers
Carolina Panthers
0.5 14 7 0 7
17
Tampa Bay Buccaneers
Tampa Bay Buccaneers
0.5 14 7 0 7

Tampa Bay Buccaneers and Carolina Panthers Latest Matches

Tampa Bay Buccaneers
Tampa Bay Buccaneers Latest matches
L L L W L L
Victories

1/6 (17%)

Draw

0/6 (0%)

Defeats

5/6 (83%)

Dec 11, 2025 - NFL

Atlanta Falcons
29 :  28
Tampa Bay Buccaneers

Dec 7, 2025 - NFL

New Orleans Saints
24 :  20
Tampa Bay Buccaneers

Nov 30, 2025 - NFL

Arizona Cardinals
17 :  20
Tampa Bay Buccaneers

Nov 23, 2025 - NFL

Tampa Bay Buccaneers
7 :  34
Los Angeles Rams

Nov 16, 2025 - NFL

Tampa Bay Buccaneers
32 :  44
Buffalo Bills

Nov 9, 2025 - NFL

New England Patriots
28 :  23
Tampa Bay Buccaneers
L W L W L L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Dec 11, 2025 - NFL

Atlanta Falcons
29 :  28
Tampa Bay Buccaneers

Dec 7, 2025 - NFL

New Orleans Saints
24 :  20
Tampa Bay Buccaneers

Nov 30, 2025 - NFL

Arizona Cardinals
17 :  20
Tampa Bay Buccaneers

Nov 9, 2025 - NFL

New England Patriots
28 :  23
Tampa Bay Buccaneers

Oct 12, 2025 - NFL

San Francisco 49ers
19 :  30
Tampa Bay Buccaneers

Sep 28, 2025 - NFL

Philadelphia Eagles
31 :  25
Tampa Bay Buccaneers
W W L W L L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Nov 23, 2025 - NFL

Tampa Bay Buccaneers
7 :  34
Los Angeles Rams

Nov 16, 2025 - NFL

Tampa Bay Buccaneers
32 :  44
Buffalo Bills

Oct 26, 2025 - NFL

Tampa Bay Buccaneers
23 :  3
New Orleans Saints

Oct 20, 2025 - NFL

Tampa Bay Buccaneers
9 :  24
Detroit Lions

Oct 5, 2025 - NFL

Tampa Bay Buccaneers
38 :  35
Seattle Seahawks

Sep 15, 2025 - NFL

Tampa Bay Buccaneers
20 :  19
Houston Texans
Carolina Panthers
Carolina Panthers Latest matches
W L W L W L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Dec 14, 2025 - NFL

Carolina Panthers
17 :  20
New Orleans Saints

Nov 30, 2025 - NFL

Los Angeles Rams
28 :  31
Carolina Panthers

Nov 24, 2025 - NFL

Carolina Panthers
9 :  20
San Francisco 49ers

Nov 16, 2025 - NFL

Carolina Panthers
30 :  27
Atlanta Falcons

Nov 9, 2025 - NFL

New Orleans Saints
17 :  7
Carolina Panthers

Nov 2, 2025 - NFL

Carolina Panthers
16 :  13
Green Bay Packers
W W W L L W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 30, 2025 - NFL

Los Angeles Rams
28 :  31
Carolina Panthers

Nov 9, 2025 - NFL

New Orleans Saints
17 :  7
Carolina Panthers

Oct 26, 2025 - NFL

Buffalo Bills
40 :  9
Carolina Panthers

Oct 12, 2025 - NFL

Dallas Cowboys
27 :  30
Carolina Panthers

Oct 5, 2025 - NFL

Miami Dolphins
24 :  27
Carolina Panthers

Sep 21, 2025 - NFL

Atlanta Falcons
0 :  30
Carolina Panthers
L W W W L L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Dec 14, 2025 - NFL

Carolina Panthers
17 :  20
New Orleans Saints

Nov 24, 2025 - NFL

Carolina Panthers
9 :  20
San Francisco 49ers

Nov 16, 2025 - NFL

Carolina Panthers
30 :  27
Atlanta Falcons

Nov 2, 2025 - NFL

Carolina Panthers
16 :  13
Green Bay Packers

Oct 19, 2025 - NFL

Carolina Panthers
13 :  6
New York Jets

Sep 28, 2025 - NFL

Carolina Panthers
13 :  42
New England Patriots

Tampa Bay Buccaneers against Carolina Panthers : Head to Head (H2H)

Tampa Bay Buccaneers

100 %

Draw

0 %

Carolina Panthers

0 %

Dec 29, 2024 - NFL

Carolina Panthers
14 :  48
Tampa Bay Buccaneers

Jan 7, 2024 - NFL

Tampa Bay Buccaneers
9 :  0
Carolina Panthers

Dec 3, 2023 - NFL

Carolina Panthers
18 :  21
Tampa Bay Buccaneers

Tampa Bay Buccaneers - Carolina Panthers Key Points

  1. Carolina is 1-5 SU in its last 6 games when playing at home against Tampa Bay.
  2. Carolina is 12-5 ATS in its last 17 games against an opponent in the National Football Conference conference.
  3. Tampa Bay is 1-5 SU in its last 6 games.
  4. Tampa Bay is 1-4 SU in its last 5 games.

Our Tampa Bay Buccaneers vs Carolina Panthers Prediction

Forecast: Carolina is 1-5 SU in its last 6 games when playing at home against Tampa Bay, while Tampa Bay is 1-5 SU in its last 6 games. This is a tricky game to pick a winner, but I am leaning toward the home team to pull off the win. Carolina is 4-2 on their turf this season. The Buccaneers would not allow their postseason streak to end, but their defence hasn’t performed well in their last six games. Meanwhile, the Panthers showed they can take down elite-level squads when everything is going their way, as they shocked the LA Rams, 31-28, two weeks ago.

Our betting prediction for the Tampa Bay Buccaneers vs. the Carolina Panthers: The Panthers will win.

Prediction:

 

The Panthers will win

+124
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Tampa Bay Buccaneers vs Carolina Panthers Picks