Los Angeles Chargers vs Jacksonville Jaguars Prediction & Picks - NFL

USA - NFL

Los Angeles Chargers
11/16/25 13:00
Jacksonville Jaguars

Prediction:

 

Less than 43.5 goals

-105
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 by Erik Gibbs in NFL Picks

The Week 11 matchup between the Los Angeles Chargers and the Jacksonville Jaguars at EverBank Stadium brings together two teams headed in very different directions. Los Angeles rolls into this game at 7-3 and riding the momentum of a convincing 25-10 win over Pittsburgh, a performance that highlighted their balance on both sides of the ball. Jacksonville, meanwhile, is looking to steady itself after dropping a 36-29 shootout to Houston, a loss that pushed them to 5-4 and exposed lingering defensive issues that have cropped up repeatedly this season.

The Chargers have quietly built one of the more efficient offenses in the league. They rank seventh in passing yards per game, leaning on a consistent aerial attack that complements a top-10 rushing offense. That balance has helped them average 24 points per contest, a number that keeps them competitive even when the pace quickens. Defensively, Los Angeles has also shown real stability. They sit eighth in scoring defense, keeping opponents to just over 20 points per game. That combination of steady quarterback play, a reliable run game, and a defense that rarely breaks makes them one of the more complete teams through ten weeks.

Jacksonville's statistical profile tells a different story. While the Jaguars sit near the league's midpoint in both passing and rushing yardage, they lack the sharp execution that separates contenders from teams still trying to find their rhythm. Their scoring offense is slightly below league average, and their defense has struggled to get off the field in key moments, allowing more than 24 points per game. Last week's collapse against Houston, where they allowed 26 points in the fourth quarter alone, highlights just how volatile this group can be. Injuries to several top receivers also cloud their offensive outlook heading into Sunday.

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Los Angeles Chargers vs Jacksonville Jaguars Form

Table

Teams % P W D L
7
Los Angeles Chargers
Los Angeles Chargers
0.7 10 7 0 3
15
Jacksonville Jaguars
Jacksonville Jaguars
0.556 9 5 0 4

Los Angeles Chargers and Jacksonville Jaguars Latest Matches

Los Angeles Chargers
Los Angeles Chargers Latest matches
L W L W W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 9, 2025 - NFL

Pittsburgh Steelers
10 :  25
Los Angeles Chargers

Nov 2, 2025 - NFL

Los Angeles Chargers
27 :  20
Tennessee Titans

Oct 23, 2025 - NFL

Minnesota Vikings
10 :  37
Los Angeles Chargers

Oct 19, 2025 - NFL

Indianapolis Colts
38 :  24
Los Angeles Chargers

Oct 12, 2025 - NFL

Los Angeles Chargers
29 :  27
Miami Dolphins

Oct 5, 2025 - NFL

Washington Commanders
27 :  10
Los Angeles Chargers
W W L L W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 9, 2025 - NFL

Pittsburgh Steelers
10 :  25
Los Angeles Chargers

Oct 23, 2025 - NFL

Minnesota Vikings
10 :  37
Los Angeles Chargers

Oct 19, 2025 - NFL

Indianapolis Colts
38 :  24
Los Angeles Chargers

Oct 5, 2025 - NFL

Washington Commanders
27 :  10
Los Angeles Chargers

Sep 21, 2025 - NFL

Denver Broncos
20 :  23
Los Angeles Chargers

Sep 5, 2025 - NFL

Kansas City Chiefs
21 :  27
Los Angeles Chargers
W L W L W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 2, 2025 - NFL

Los Angeles Chargers
27 :  20
Tennessee Titans

Oct 12, 2025 - NFL

Los Angeles Chargers
29 :  27
Miami Dolphins

Sep 28, 2025 - NFL

Los Angeles Chargers
18 :  21
New York Giants

Sep 15, 2025 - NFL

Los Angeles Chargers
20 :  9
Las Vegas Raiders

Jan 11, 2025 - NFL

Los Angeles Chargers
12 :  32
Houston Texans

Jan 5, 2025 - NFL

Los Angeles Chargers
34 :  20
Las Vegas Raiders
Jacksonville Jaguars
Jacksonville Jaguars Latest matches
W W L L W L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Nov 9, 2025 - NFL

Jacksonville Jaguars
29 :  36
Houston Texans

Nov 2, 2025 - NFL

Jacksonville Jaguars
30 :  29
Las Vegas Raiders

Oct 19, 2025 - NFL

Los Angeles Rams
35 :  7
Jacksonville Jaguars

Oct 12, 2025 - NFL

Seattle Seahawks
20 :  12
Jacksonville Jaguars

Oct 6, 2025 - NFL

Kansas City Chiefs
28 :  31
Jacksonville Jaguars

Sep 28, 2025 - NFL

Jacksonville Jaguars
26 :  21
San Francisco 49ers
W W W W L L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Oct 19, 2025 - NFL

Los Angeles Rams
35 :  7
Jacksonville Jaguars

Oct 12, 2025 - NFL

Seattle Seahawks
20 :  12
Jacksonville Jaguars

Oct 6, 2025 - NFL

Kansas City Chiefs
28 :  31
Jacksonville Jaguars

Sep 21, 2025 - NFL

Houston Texans
10 :  17
Jacksonville Jaguars

Sep 7, 2025 - NFL

Carolina Panthers
10 :  26
Jacksonville Jaguars

Dec 29, 2024 - NFL

Tennessee Titans
13 :  20
Jacksonville Jaguars
L L L W W L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Nov 9, 2025 - NFL

Jacksonville Jaguars
29 :  36
Houston Texans

Nov 2, 2025 - NFL

Jacksonville Jaguars
30 :  29
Las Vegas Raiders

Sep 28, 2025 - NFL

Jacksonville Jaguars
26 :  21
San Francisco 49ers

Sep 14, 2025 - NFL

Jacksonville Jaguars
27 :  31
Cincinnati Bengals

Jan 5, 2025 - NFL

Jacksonville Jaguars
23 :  26
Indianapolis Colts

Dec 22, 2024 - NFL

Jacksonville Jaguars
14 :  19
Las Vegas Raiders

Los Angeles Chargers against Jacksonville Jaguars : Head to Head (H2H)

Los Angeles Chargers

50 %

Draw

0 %

Jacksonville Jaguars

50 %

Jan 14, 2023 - NFL

Los Angeles Chargers
30 :  31
Jacksonville Jaguars

Oct 25, 2020 - NFL

Jacksonville Jaguars
29 :  39
Los Angeles Chargers

Los Angeles Chargers - Jacksonville Jaguars Key Points

  1. The Over is 0-6 in the Jaguars’ last 6 games as underdogs after a road loss
  2. The Over is 0-4 in the last four Sunday games at EverBank Stadium
  3. The Jaguars are 3-0 in their last 3 November games as home underdogs vs. AFC teams
  4. The Chargers are 1-3 in their last 4 games as road favorites vs. AFC South teams
Up to $500+ to bet on Los Angeles Chargers - Jacksonville Jaguars! 

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Our Los Angeles Chargers vs Jacksonville Jaguars Prediction

The historical matchup favors Los Angeles, holding a 9-4 edge in the regular season series. However, Jacksonville did deliver a dominant 38-10 win the last time these teams met in 2022. The question is whether the Jaguars, as currently constructed and significantly less healthy, can replicate anything close to that performance.

Totals trends point to another interesting layer. The Chargers have split their ten games in relation to the number but have hit the over in four of their last five overall, including each of their last two on the road. Jacksonville's pattern is more split: they have gone over in all four road games but stayed under in four of five at home. Given how leaky their defense has looked and how consistently the Chargers have moved the football, this matchup has the potential to turn into another high-scoring affair, especially if Jacksonville again struggles to contain explosive plays late.

With Los Angeles healthier, more consistent, and better equipped to control the tempo, the Chargers enter Week 11 as the more trustworthy side. Jacksonville will need a cleaner defensive effort and a more stable fourth quarter than they've shown in recent weeks to avoid falling back into the AFC pack. Our prediction for the Jacksonville Jaguars vs. Los Angeles Chargers: Under 43.5 points.

Prediction:

 

Less than 43.5 goals

-105
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Los Angeles Chargers vs Jacksonville Jaguars Picks