Kentucky Wildcats vs Vanderbilt Commodores Prediction & Picks - NCAA

USA - NCAA

Kentucky Wildcats
11/22/25 15:30
Vanderbilt Commodores

Prediction:

 

Kentucky +9.5

-105
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 by Travis Pulver in NCAA Picks

The No. 14 Vanderbilt Commodores will try to keep their CFP hopes alive when they host the Kentucky Wildcats Saturday afternoon at FirstBank Stadium in Nashville, TN. Kickoff for this important SEC clash is scheduled for 3:30 p.m. EST on ESPN.

After a disappointing loss to Texas a couple of weeks ago, the Commodores bounced back last week with a solid 45-38 win over Auburn. Diego Pavia was up to his usual tricks, throwing for 377 yards and three touchdowns while adding another 112 yards and a score on the ground. He’ll have his work cut out for him against a Kentucky defense that has been playing better lately than their stats would indicate. For the Wildcats, it’s really been a tale of two seasons as they started conference play with four losses but have bounced back with three straight wins (including two SEC victories). The secret? Kentucky has been playing solid defense and running the ball really well. It will not be easy against Vany’s 24th-ranked run defense, but if they can establish the run, they’ll have a real shot at an upset

The stakes are certainly higher for Vanderbilt in this game, but Kentucky needs a win to become bowl-eligible.

Kentucky Wildcats vs Vanderbilt Commodores Form

Table

Teams % P W D L
7
Vanderbilt Commodores
Vanderbilt Commodores
0.667 6 4 0 2
12
Kentucky Wildcats
Kentucky Wildcats
0.286 7 2 0 5

Kentucky Wildcats and Vanderbilt Commodores Latest Matches

Kentucky Wildcats
Kentucky Wildcats Latest matches
L L L W W W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Nov 15, 2025 - NCAA

Tennessee Tech Golden Eagles
10 :  42
Kentucky Wildcats

Nov 8, 2025 - NCAA

Florida Gators
7 :  38
Kentucky Wildcats

Nov 1, 2025 - NCAA

Kentucky Wildcats
10 :  3
Auburn Tigers

Oct 25, 2025 - NCAA

Tennessee Volunteers
56 :  34
Kentucky Wildcats

Oct 18, 2025 - NCAA

Texas Longhorns
16 :  13
Kentucky Wildcats

Oct 4, 2025 - NCAA

Kentucky Wildcats
14 :  35
Georgia Bulldogs
L W L L W W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Nov 15, 2025 - NCAA

Tennessee Tech Golden Eagles
10 :  42
Kentucky Wildcats

Nov 8, 2025 - NCAA

Florida Gators
7 :  38
Kentucky Wildcats

Oct 25, 2025 - NCAA

Tennessee Volunteers
56 :  34
Kentucky Wildcats

Oct 18, 2025 - NCAA

Texas Longhorns
16 :  13
Kentucky Wildcats

Sep 13, 2025 - NCAA

Eastern Michigan Eagles
23 :  48
Kentucky Wildcats

Sep 6, 2025 - NCAA

Ole Miss Rebels
30 :  23
Kentucky Wildcats
W L L L W
Victories

2/5 (40%)

Draw

0/5 (0%)

Defeats

3/5 (60%)

Nov 1, 2025 - NCAA

Kentucky Wildcats
10 :  3
Auburn Tigers

Oct 4, 2025 - NCAA

Kentucky Wildcats
14 :  35
Georgia Bulldogs

Sep 27, 2025 - NCAA

Kentucky Wildcats
13 :  35
South Carolina Gamecocks

Nov 23, 2024 - NCAA

Kentucky Wildcats
14 :  31
Texas Longhorns

Sep 28, 2024 - NCAA

Kentucky Wildcats
20 :  17
Ole Miss Rebels
Vanderbilt Commodores
Vanderbilt Commodores Latest matches
W L W W L W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 8, 2025 - NCAA

Auburn Tigers
38 :  45
Vanderbilt Commodores

Nov 1, 2025 - NCAA

Vanderbilt Commodores
31 :  34
Texas Longhorns

Oct 25, 2025 - NCAA

Missouri Tigers
10 :  17
Vanderbilt Commodores

Oct 18, 2025 - NCAA

LSU Tigers
24 :  31
Vanderbilt Commodores

Oct 4, 2025 - NCAA

Vanderbilt Commodores
14 :  30
Alabama Crimson Tide

Sep 27, 2025 - NCAA

Utah State Aggies
35 :  55
Vanderbilt Commodores
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Nov 8, 2025 - NCAA

Auburn Tigers
38 :  45
Vanderbilt Commodores

Oct 25, 2025 - NCAA

Missouri Tigers
10 :  17
Vanderbilt Commodores

Oct 18, 2025 - NCAA

LSU Tigers
24 :  31
Vanderbilt Commodores

Sep 27, 2025 - NCAA

Utah State Aggies
35 :  55
Vanderbilt Commodores

Sep 20, 2025 - NCAA

Georgia State Panthers
21 :  70
Vanderbilt Commodores

Aug 30, 2025 - NCAA

Charleston Southern Buccaneers
3 :  45
Vanderbilt Commodores
L L W W L L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Nov 1, 2025 - NCAA

Vanderbilt Commodores
31 :  34
Texas Longhorns

Oct 4, 2025 - NCAA

Vanderbilt Commodores
14 :  30
Alabama Crimson Tide

Sep 13, 2025 - NCAA

Vanderbilt Commodores
31 :  7
South Carolina Gamecocks

Sep 6, 2025 - NCAA

Vanderbilt Commodores
44 :  20
Virginia Tech Hokies

Nov 23, 2024 - NCAA

Vanderbilt Commodores
17 :  24
LSU Tigers

Sep 21, 2024 - NCAA

Vanderbilt Commodores
27 :  30
Missouri Tigers

Kentucky Wildcats - Vanderbilt Commodores Key Points

  1. Kentucky leads the all-time series vs. Vanderbilt, 48-44-4, but Vanderbilt has won two of the last three.
  2. Vanderbilt is 7-2-1 ATS this season while Kentucky is 5-5.
  3. The OVER is 7-3 for both teams this season.
  4. Betting Public: 35% of spread tickets and 40% of the handle are on Kentucky.

Our Kentucky Wildcats vs Vanderbilt Commodores Prediction

Matchups like this can be confusing: do you go with the team that has played better all season long or the hot hand? Vanderbilt is definitely the better of the two teams this season, but the Wildcats are on a roll with three wins in a row. Kentucky’s run game has been getting the job done, and the defense has been stingy. As great as Vanderbilt has been, three of their four SEC wins were by a touchdown.

Our Kentucky vs. Tennessee Pick: Kentucky +9.5

Prediction:

 

Kentucky +9.5

-105
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Kentucky Wildcats vs Vanderbilt Commodores Picks