New York Jets vs Buffalo Bills Prediction & Picks - NFL

USA - NFL

New York Jets
11/15/26 13:00
Buffalo Bills

Prediction:

 

Buffalo Bills -8.5

−105
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 by Matt Lowrimore | in NFL Picks

The Week 10 NFL Sunday slate will feature 12 games, one of which will be an AFC East matchup between the New York Jets and the Buffalo Bills. Let’s take a look at the match statistics and predictions for this game between the Jets and the Bills.

Buffalo enters this game with a record of 7-1 and is coming off a 23-6 road win against the Minnesota Vikings in Week 9. The Bills have easily been one of the best teams in the league this season, which is partly thanks to the fact that they are a perfect 4-0 straight up on the road this season. Buffalo has particularly been efficient offensively, as they are averaging 32.0 points per game and should continue their success against New York. 

As for New York, they enter this game with a record of 2-7. The Jets are coming off their fourth loss in a row in Week 9, as they fell to the Kansas City Chiefs by a score of 35-12. As they have for most of the season, New York looked toothless offensively and could not stop a superior offense in the Chiefs. The same result looks likely here, as Buffalo surpasses them in nearly every category.

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New York Jets vs Buffalo Bills Form

Table

Teams Pts P W L
1 Buffalo Bills
0.875 8 7 1
28 New York Jets
0.222 9 2 7

New York Jets and Buffalo Bills Latest Matches

New York Jets
New York Jets Latest matches
L W L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Nov 8, 2026 - NFL

Kansas City Chiefs
35 :  12
New York Jets

Nov 1, 2026 - NFL

New York Jets
33 :  38
Las Vegas Raiders

Oct 25, 2026 - NFL

New York Jets
25 :  28
Miami Dolphins

Oct 18, 2026 - NFL

New England Patriots
26 :  19
New York Jets

Oct 11, 2026 - NFL

New York Jets
17 :  12
Cleveland Browns

Oct 4, 2026 - NFL

Chicago Bears
23 :  12
New York Jets
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Nov 1, 2026 - NFL

New York Jets
33 :  38
Las Vegas Raiders

Oct 25, 2026 - NFL

New York Jets
25 :  28
Miami Dolphins

Oct 11, 2026 - NFL

New York Jets
17 :  12
Cleveland Browns

Sep 20, 2026 - NFL

New York Jets
17 :  20
Green Bay Packers

Dec 28, 2025 - NFL

New York Jets
10 :  42
New England Patriots

Dec 7, 2025 - NFL

New York Jets
10 :  34
Miami Dolphins
L W L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Nov 8, 2026 - NFL

Kansas City Chiefs
35 :  12
New York Jets

Oct 18, 2026 - NFL

New England Patriots
26 :  19
New York Jets

Oct 4, 2026 - NFL

Chicago Bears
23 :  12
New York Jets

Sep 27, 2026 - NFL

Detroit Lions
31 :  24
New York Jets

Sep 13, 2026 - NFL

Tennessee Titans
10 :  23
New York Jets

Jan 4, 2026 - NFL

Buffalo Bills
35 :  8
New York Jets
Buffalo Bills
Buffalo Bills Latest matches
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Nov 9, 2026 - NFL

Minnesota Vikings
6 :  23
Buffalo Bills

Nov 1, 2026 - NFL

Buffalo Bills
36 :  10
Baltimore Ravens

Oct 18, 2026 - NFL

Las Vegas Raiders
30 :  33
Buffalo Bills

Oct 12, 2026 - NFL

Los Angeles Rams
34 :  37
Buffalo Bills

Oct 4, 2026 - NFL

Buffalo Bills
26 :  29
New England Patriots

Sep 27, 2026 - NFL

Buffalo Bills
24 :  16
Los Angeles Chargers
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 1, 2026 - NFL

Buffalo Bills
36 :  10
Baltimore Ravens

Oct 4, 2026 - NFL

Buffalo Bills
26 :  29
New England Patriots

Sep 27, 2026 - NFL

Buffalo Bills
24 :  16
Los Angeles Chargers

Sep 17, 2026 - NFL

Buffalo Bills
41 :  31
Detroit Lions

Jan 4, 2026 - NFL

Buffalo Bills
35 :  8
New York Jets

Dec 28, 2025 - NFL

Buffalo Bills
12 :  13
Philadelphia Eagles
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Nov 9, 2026 - NFL

Minnesota Vikings
6 :  23
Buffalo Bills

Oct 18, 2026 - NFL

Las Vegas Raiders
30 :  33
Buffalo Bills

Oct 12, 2026 - NFL

Los Angeles Rams
34 :  37
Buffalo Bills

Sep 13, 2026 - NFL

Houston Texans
31 :  36
Buffalo Bills

Jan 17, 2026 - NFL

Denver Broncos
33 :  30
Buffalo Bills

Jan 11, 2026 - NFL

Jacksonville Jaguars
24 :  27
Buffalo Bills

New York Jets against Buffalo Bills : Head to Head (H2H)

New York Jets

17 %

Buffalo Bills

83 %

Jan 4, 2026 - NFL

Buffalo Bills
35 :  8
New York Jets

Sep 14, 2025 - NFL

New York Jets
10 :  30
Buffalo Bills

Dec 29, 2024 - NFL

Buffalo Bills
40 :  14
New York Jets

Oct 14, 2024 - NFL

New York Jets
20 :  23
Buffalo Bills

Nov 19, 2023 - NFL

Buffalo Bills
32 :  6
New York Jets

Sep 11, 2023 - NFL

New York Jets
22 :  16
Buffalo Bills
New York Jets vs Buffalo Bills Picks

New York Jets - Buffalo Bills Key Points

  1. Buffalo is 6-2 ATS this season
  2. Buffalo is 7-3 ATS vs. New York in the last 10 meetings
  3. New York is 4-5 ATS this season
  4. New York is 2-8 SU vs. Buffalo in the last 10 meetings
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Our New York Jets vs Buffalo Bills Prediction

Buffalo is a significant favorite in this game; however, they still look to be the best betting option. For one, the Bills are 6-2 ATS this season, while the Jets are 4-5 ATS. Further, and as mentioned previously, Buffalo is a perfect 4-0 on the road, while New York is 1-3 at home.

The Bills have also had the Jets' number over the past couple of years, as they are 8-2 SU and 7-3 ATS against them over the last 10 meetings. Facing a high-powered offense has been the biggest struggle for the Jets this season, as we saw when they lost to Kansas City last week. Therefore, because Buffalo has arguably the best offense in the NFL, our New York Jets vs. Buffalo Bills prediction is: Buffalo Bills -8.5.

Prediction:

 

Buffalo Bills -8.5

−105
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.