Mississippi State Bulldogs vs Missouri Tigers Prediction & Picks - NCAA
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by Matt Lowrimore | in NCAA Picks
Week 4 of the College Football season continues on Saturday with a full slate of games, one of which will include an SEC matchup between the 19th-ranked Missouri Tigers and the 24th-ranked Mississippi State Bulldogs. Let's take a look at the match statistics and predictions for this game between the Tigers and the Bulldogs.
Missouri enters this game with a record of 3-0, but will be facing their first SEC opponent. The Tigers came off a 27-17 win against the Troy Trojans. The issue is that Missouri had just 230 yards of offense; however, they should have more success against the Bulldogs, with this being their first SEC game of the season.
As for Mississippi State, they also enter this game with a record of 3-0, and they are 1-0 in the SEC. The Bulldogs came off a 41-34 win over the South Carolina Gamecocks in Week 3, where they produced 393 yards of offense while allowing 431 yards. It has been a strong start for Mississippi State; however, they have Alabama looming in Week 5, so this has the potential to be a lookahead game for them.
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Mississippi State Bulldogs vs Missouri Tigers Form
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Mississippi State Bulldogs and Missouri Tigers Latest Matches
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3/6 (50%)
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4/6 (67%)
2/6 (33%)
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3/6 (50%)
3/6 (50%)
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3/6 (50%)
3/6 (50%)
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Mississippi State Bulldogs against Missouri Tigers : Head to Head (H2H)
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Nov 15, 2025 - NCAA
Mississippi State Bulldogs - Missouri Tigers Key Points
- Missouri is 1-0 SU on the road this season
- Missouri is 1-0 ATS on the road this season
- Mississippi State is 3-0 ATS this season
- Mississippi State is 1-0 SU at home this season
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Our Mississippi State Bulldogs vs Missouri Tigers Prediction
Mississippi State is a touchdown favorite in this game; however, Missouri looks to be the best betting option. As mentioned, the Bulldogs have Alabama waiting for them in Week 5, and while this should not affect them too much, there is still likely to be some lookahead aspect.
There is also the fact that while Mississippi State has yet to lose, their defense has still not been the most reliable. The same goes for Missouri's offense, which struggled for large stretches of their game with Troy.
Despite that, this game still looks as if it will be competitive, with two improving SEC teams going against each other. For that reason, our Missouri Tigers vs. Mississippi State Bulldogs prediction is: Missouri Tigers +7.5 Alternate Spread.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.