Mississippi State Bulldogs vs Missouri Tigers Prediction & Picks - NCAA

USA - NCAA

Mississippi State Bulldogs
9/26/26 19:45
Missouri Tigers

Prediction:

 

Missouri Tigers +7.5 Alternate Spread

-153
$150 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Matt Lowrimore | in NCAA Picks

Week 4 of the College Football season continues on Saturday with a full slate of games, one of which will include an SEC matchup between the 19th-ranked Missouri Tigers and the 24th-ranked Mississippi State Bulldogs. Let's take a look at the match statistics and predictions for this game between the Tigers and the Bulldogs.

Missouri enters this game with a record of 3-0, but will be facing their first SEC opponent. The Tigers came off a 27-17 win against the Troy Trojans. The issue is that Missouri had just 230 yards of offense; however, they should have more success against the Bulldogs, with this being their first SEC game of the season. 

As for Mississippi State, they also enter this game with a record of 3-0, and they are 1-0 in the SEC. The Bulldogs came off a 41-34 win over the South Carolina Gamecocks in Week 3, where they produced 393 yards of offense while allowing 431 yards. It has been a strong start for Mississippi State; however, they have Alabama looming in Week 5, so this has the potential to be a lookahead game for them.

Mississippi State Bulldogs vs Missouri Tigers Form

Table

Mississippi State Bulldogs and Missouri Tigers Latest Matches

Mississippi State Bulldogs
Mississippi State Bulldogs Latest matches
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 19, 2026 - NCAA

South Carolina Gamecocks
34 :  41
Mississippi State Bulldogs

Sep 12, 2026 - NCAA

Minnesota Golden Gophers
13 :  38
Mississippi State Bulldogs

Sep 5, 2026 - NCAA

Mississippi State Bulldogs
62 :  13
Louisiana-Monroe Warhawks

Jan 2, 2026 - NCAA Division I, FBS, Playoffs

Mississippi State Bulldogs
29 :  43
Wake Forest Demon Deacons

Nov 28, 2025 - NCAA

Mississippi State Bulldogs
19 :  38
Ole Miss Rebels

Nov 15, 2025 - NCAA

Missouri Tigers
49 :  27
Mississippi State Bulldogs
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Sep 5, 2026 - NCAA

Mississippi State Bulldogs
62 :  13
Louisiana-Monroe Warhawks

Jan 2, 2026 - NCAA Division I, FBS, Playoffs

Mississippi State Bulldogs
29 :  43
Wake Forest Demon Deacons

Nov 28, 2025 - NCAA

Mississippi State Bulldogs
19 :  38
Ole Miss Rebels

Nov 8, 2025 - NCAA

Mississippi State Bulldogs
21 :  41
Georgia Bulldogs

Oct 25, 2025 - NCAA

Mississippi State Bulldogs
38 :  45
Texas Longhorns

Sep 27, 2025 - NCAA

Mississippi State Bulldogs
34 :  41
Tennessee Volunteers
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 19, 2026 - NCAA

South Carolina Gamecocks
34 :  41
Mississippi State Bulldogs

Sep 12, 2026 - NCAA

Minnesota Golden Gophers
13 :  38
Mississippi State Bulldogs

Nov 15, 2025 - NCAA

Missouri Tigers
49 :  27
Mississippi State Bulldogs

Nov 1, 2025 - NCAA

Arkansas Razorbacks
35 :  38
Mississippi State Bulldogs

Oct 18, 2025 - NCAA

Florida Gators
23 :  21
Mississippi State Bulldogs

Oct 4, 2025 - NCAA

Texas A&M Aggies
31 :  9
Mississippi State Bulldogs
Missouri Tigers
Missouri Tigers Latest matches
L W L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 19, 2026 - NCAA

Missouri Tigers
27 :  17
Troy Trojans

Sep 11, 2026 - NCAA

Kansas Jayhawks
21 :  38
Missouri Tigers

Sep 3, 2026 - NCAA

Missouri Tigers
54 :  14
Arkansas-Pine Bluff Golden Lions

Dec 27, 2025 - NCAA Division I, FBS, Playoffs

Missouri Tigers
7 :  13
Virginia Cavaliers

Nov 29, 2025 - NCAA

Arkansas Razorbacks
17 :  31
Missouri Tigers

Nov 22, 2025 - NCAA

Oklahoma Sooners
17 :  6
Missouri Tigers
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 19, 2026 - NCAA

Missouri Tigers
27 :  17
Troy Trojans

Sep 3, 2026 - NCAA

Missouri Tigers
54 :  14
Arkansas-Pine Bluff Golden Lions

Dec 27, 2025 - NCAA Division I, FBS, Playoffs

Missouri Tigers
7 :  13
Virginia Cavaliers

Nov 15, 2025 - NCAA

Missouri Tigers
49 :  27
Mississippi State Bulldogs

Nov 8, 2025 - NCAA

Missouri Tigers
17 :  38
Texas A&M Aggies

Oct 11, 2025 - NCAA

Missouri Tigers
24 :  27
Alabama Crimson Tide
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 11, 2026 - NCAA

Kansas Jayhawks
21 :  38
Missouri Tigers

Nov 29, 2025 - NCAA

Arkansas Razorbacks
17 :  31
Missouri Tigers

Nov 22, 2025 - NCAA

Oklahoma Sooners
17 :  6
Missouri Tigers

Oct 25, 2025 - NCAA

Vanderbilt Commodores
17 :  10
Missouri Tigers

Oct 18, 2025 - NCAA

Auburn Tigers
17 :  23
Missouri Tigers

Oct 5, 2024 - NCAA

Texas A&M Aggies
41 :  10
Missouri Tigers

Mississippi State Bulldogs against Missouri Tigers : Head to Head (H2H)

Mississippi State Bulldogs

0 %

Missouri Tigers

100 %

Nov 15, 2025 - NCAA

Missouri Tigers
49 :  27
Mississippi State Bulldogs
Mississippi State Bulldogs vs Missouri Tigers Picks

Mississippi State Bulldogs - Missouri Tigers Key Points

  1. Missouri is 1-0 SU on the road this season
  2. Missouri is 1-0 ATS on the road this season
  3. Mississippi State is 3-0 ATS this season
  4. Mississippi State is 1-0 SU at home this season

Our Mississippi State Bulldogs vs Missouri Tigers Prediction

Mississippi State is a touchdown favorite in this game; however, Missouri looks to be the best betting option. As mentioned, the Bulldogs have Alabama waiting for them in Week 5, and while this should not affect them too much, there is still likely to be some lookahead aspect.

There is also the fact that while Mississippi State has yet to lose, their defense has still not been the most reliable. The same goes for Missouri's offense, which struggled for large stretches of their game with Troy. 

Despite that, this game still looks as if it will be competitive, with two improving SEC teams going against each other. For that reason, our Missouri Tigers vs. Mississippi State Bulldogs prediction is: Missouri Tigers +7.5 Alternate Spread.

Prediction:

 

Missouri Tigers +7.5 Alternate Spread

-153
$150 offered for betting!

A Welcome Bonus for Mississippi State Bulldogs vs Missouri Tigers!

DraftKings Welcome Bonus 150

Looking to place a bet on Mississippi State Bulldogs vs Missouri Tigers? For this NCAA match, DraftKings will treat you to an exclusive offer: $150 in bonus bets, no promo code needed! Take advantage while you still can!

$150 in bonus bets for Mississippi State Bulldogs vs Missouri Tigers!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.