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by Travis Pulver in NFL Picks
Thursday Night Football will feature an NFC West battle with the Arizona Cardinals hosting the Seattle Seahawks at State Farm Stadium in Glendale. Kickoff is scheduled for 8:15 p.m. EST on Thursday, Sept. 25.
Arizona got off to a hot start with a win in Week 1 over the New Orleans Saints, 20-13. They followed that with another win, this time over the Carolina Panthers 27-22. But the good times were not meant to last, and they lost to the 49ers in Week 3, 16-15. The offense has been methodical and efficient this season, not explosive. Luckily, the defense has been up to the task. It ranks towards the bottom of the league in total yards allowed per game (340.7, No. 23), but towards the top in scoring (17 ppg, No. 5). As for the Seahawks, after a disappointing performance in the season opener, a 17-13 loss to the 49ers, they have bounced back with two solid wins, one vs. the Steelers (31-17) and the other vs. the Saints (44-13). Sam Darnold had an incredibly efficient game against the Saints, completing 14 of 18 passes for 218 yards and a pair of touchdowns. He is one of ten quarterbacks with a 100+ rating for the season through three weeks (104.
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Seattle Seahawks vs Arizona Cardinals Form
Table
| Teams | % | P | W | D | L |
|---|---|---|---|---|---|
|
11
|
0.667 | 3 | 2 | 0 | 1 |
|
15
|
0.667 | 3 | 2 | 0 | 1 |
Seattle Seahawks and Arizona Cardinals Latest Matches
4/6 (67%)
0/6 (0%)
2/6 (33%)
Sep 21, 2025 - NFL
Sep 14, 2025 - NFL
Sep 7, 2025 - NFL
Jan 5, 2025 - NFL
Dec 26, 2024 - NFL
Dec 22, 2024 - NFL
2/6 (33%)
0/6 (0%)
4/6 (67%)
Sep 21, 2025 - NFL
Sep 7, 2025 - NFL
Dec 22, 2024 - NFL
Dec 15, 2024 - NFL
Nov 24, 2024 - NFL
Nov 3, 2024 - NFL
6/6 (100%)
0/6 (0%)
0/6 (0%)
Sep 14, 2025 - NFL
Jan 5, 2025 - NFL
Dec 26, 2024 - NFL
Dec 8, 2024 - NFL
Dec 1, 2024 - NFL
Nov 17, 2024 - NFL
3/6 (50%)
0/6 (0%)
3/6 (50%)
Sep 21, 2025 - NFL
Sep 14, 2025 - NFL
Sep 7, 2025 - NFL
Jan 5, 2025 - NFL
Dec 28, 2024 - NFL
Dec 22, 2024 - NFL
5/6 (83%)
0/6 (0%)
1/6 (17%)
Sep 14, 2025 - NFL
Jan 5, 2025 - NFL
Dec 15, 2024 - NFL
Dec 8, 2024 - NFL
Nov 10, 2024 - NFL
Nov 3, 2024 - NFL
1/6 (17%)
0/6 (0%)
5/6 (83%)
Sep 21, 2025 - NFL
Sep 7, 2025 - NFL
Dec 28, 2024 - NFL
Dec 22, 2024 - NFL
Dec 1, 2024 - NFL
Nov 24, 2024 - NFL
Seattle Seahawks against Arizona Cardinals : Head to Head (H2H)
80 %
0 %
20 %
Dec 8, 2024 - NFL
Nov 24, 2024 - NFL
Jan 7, 2024 - NFL
Nov 6, 2022 - NFL
Oct 25, 2020 - NFL
Seattle Seahawks - Arizona Cardinals Key Points
- Seattle leads the all-time series vs. Arizona 29-22-1 and has won eight of the last ten meetings.
- The OVER is 16-16 in division games for Arizona since 2020; the OVER is 13-20 for Seattle in division games since 2020.
- Arizona is 13-19 ATS in division games since 2020; Seattle is 14-19 ATS in division games since 2020.
- Betting Public: In early returns, 59% of moneyline tickets are on Arizona, but 91% of the handle is on Seattle.
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Our Seattle Seahawks vs Arizona Cardinals Prediction
It is hard to know just what to think about either team heading into this game. The Arizona defense played well vs. the Saints and Panthers in their two wins. But the offense was only sufficient, and it's not like either team is very good. Seattle beat up a poor Sanits team but played well overall against a decent Steelers team. I have to go with the Seahawks. Both defenses appear to be solid, but the Seattle offense has shown more signs of life. In the end, I think they’ll find a way to win.
Our Seahawks vs. Cardinals: Seattle ML
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
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