Manchester United vs Lyon Prediction & Picks - Europa League

Europe - Europa League

Manchester United
4/17/25 15:00
Lyon

Prediction:

 

Manuel Ugarte to Get a Card

+280
$1500 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Bradley Gibbs in Europa League Picks

One of Thursday's four Europa League clashes will see Man United and Lyon conclude their quarter-final business at Old Trafford, where the Red Devils will be hoping to make home advantge pay having tied away from home in France last week. 

It looked for all to see that Ruben Amorim's men had picked up a smash-and-grab win in Lyon last week, scoring late in the day through Joshua Zirkee, who despite being a forward, seemed an unlikely scorer. However, the hosts, who had the better of the game for the most part, had other ideas, tying the game at 2-2 through Rayan Cherki, who pounced on a rebound in the 95th minute. 

After taking a beating at the weekend, the hosts need to steady themselves for what is clearly their biggest game of the season. This is also huge for the visitors, but they'll go to Manchester off the back of a confidence-boosting win. 

Up to $1500 to bet on Manchester United - Lyon! 

Limited Offer. Currently at BetMGM

Manchester United vs Lyon Form

Manchester United and Lyon Latest Matches

Manchester United
Manchester United Latest matches
W W L D D L
Victories

2/6 (33%)

Draw

2/6 (33%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

3 Total goals
50% BTTS
1.67 Goals scored
1.33 Goals conceded
67% Over 2.5
33% Under 2.5

Apr 13, 2025 - Premier League

Newcastle
4 :  1
Manchester United

Apr 10, 2025 - Europa League

Lyon
2 :  2
Manchester United

Apr 6, 2025 - Premier League

Manchester United
0 :  0
Manchester City

Apr 1, 2025 - Premier League

Nottingham Forest
1 :  0
Manchester United

Mar 16, 2025 - Premier League

Leicester
0 :  3
Manchester United

Mar 13, 2025 - Europa League

Manchester United
4 :  1
Real Sociedad
W W D D W D
Victories

3/6 (50%)

Draw

3/6 (50%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

2.83 Total goals
83% BTTS
1.83 Goals scored
1 Goals conceded
50% Over 2.5
50% Under 2.5

Apr 6, 2025 - Premier League

Manchester United
0 :  0
Manchester City

Mar 13, 2025 - Europa League

Manchester United
4 :  1
Real Sociedad

Mar 9, 2025 - Premier League

Manchester United
1 :  1
Arsenal

Mar 2, 2025 - FA Cup

Manchester United
1 :  1
Fulham

Feb 26, 2025 - Premier League

Manchester United
3 :  2
Ipswich Town

Feb 7, 2025 - FA Cup

Manchester United
2 :  1
Leicester
D D W L D L
Victories

1/6 (17%)

Draw

3/6 (50%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

3.17 Total goals
67% BTTS
1.5 Goals scored
1.67 Goals conceded
67% Over 2.5
33% Under 2.5

Apr 13, 2025 - Premier League

Newcastle
4 :  1
Manchester United

Apr 10, 2025 - Europa League

Lyon
2 :  2
Manchester United

Apr 1, 2025 - Premier League

Nottingham Forest
1 :  0
Manchester United

Mar 16, 2025 - Premier League

Leicester
0 :  3
Manchester United

Mar 6, 2025 - Europa League

Real Sociedad
1 :  1
Manchester United

Feb 22, 2025 - Premier League

Everton
2 :  2
Manchester United
Lyon
Lyon Latest matches
W W L W D W
Victories

4/6 (67%)

Draw

1/6 (17%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

4.5 Total goals
83% BTTS
2.83 Goals scored
1.67 Goals conceded
100% Over 2.5
0% Under 2.5

Apr 13, 2025 - Ligue 1

Auxerre
1 :  3
Lyon

Apr 10, 2025 - Europa League

Lyon
2 :  2
Manchester United

Apr 5, 2025 - Ligue 1

Lyon
2 :  1
Lille

Mar 28, 2025 - Ligue 1

Strasbourg
4 :  2
Lyon

Mar 16, 2025 - Ligue 1

Lyon
4 :  2
Le Havre

Mar 13, 2025 - Europa League

Lyon
4 :  0
Fotbal Club Fcsb
L W W W W D
Victories

4/6 (67%)

Draw

1/6 (17%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

4.17 Total goals
83% BTTS
2.67 Goals scored
1.5 Goals conceded
100% Over 2.5
0% Under 2.5

Apr 10, 2025 - Europa League

Lyon
2 :  2
Manchester United

Apr 5, 2025 - Ligue 1

Lyon
2 :  1
Lille

Mar 16, 2025 - Ligue 1

Lyon
4 :  2
Le Havre

Mar 13, 2025 - Europa League

Lyon
4 :  0
Fotbal Club Fcsb

Mar 2, 2025 - Ligue 1

Lyon
2 :  1
Brest

Feb 23, 2025 - Ligue 1

Lyon
2 :  3
PSG
L W W W L W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

4.33 Total goals
83% BTTS
2.67 Goals scored
1.67 Goals conceded
83% Over 2.5
17% Under 2.5

Apr 13, 2025 - Ligue 1

Auxerre
1 :  3
Lyon

Mar 28, 2025 - Ligue 1

Strasbourg
4 :  2
Lyon

Mar 9, 2025 - Ligue 1

Nice
0 :  2
Lyon

Mar 6, 2025 - Europa League

Fotbal Club Fcsb
1 :  3
Lyon

Feb 16, 2025 - Ligue 1

Montpellier Hsc
1 :  4
Lyon

Feb 2, 2025 - Ligue 1

Marseille
3 :  2
Lyon

Manchester United against Lyon : Head to Head (H2H)

Apr 10, 2025 - Europa League

Lyon
2 :  2
Manchester United

Manchester United - Lyon: Form Analysis

On the domestic front, Manchester United have not been brilliant this season. Having exited the Carabao Cup and FA Cup early on, the Mancunian club is also not playing a leading role in the Premier League. They have taken just one point from their previous 3 matches and are only 14th in the English league. Last weekend, the team coached by Ruben Amorim suffered a heavy defeat at the hands of Newcastle United (4-1). The Red Devils are better off in the Europa League. After finishing 3rd in the Europa League, league phase, Manchester United overcame Real Sociedad in the Round of 16 (aggregate score: 5-2). Despite a far from convincing performance, United were confident of victory in the first leg of their quarter-final on the Lyon pitch. However, they conceded the equaliser in the dying moments (2-2).

Lyon snatched a last-gasp draw in the first leg of their Europa League quarter-final (2-2).

Lyon are therefore still alive ahead of the second leg of their Europa League quarter-final. The Rhône-Alpes club has been on top form since the start of this Europa League campaign. They finished in 6th place in the league phase, before not shaking against FCSB in the Round of 8 (aggregate score: 7-1). Lyon's Ligue 1 rivals have returned to top form since the arrival of Paulo Fonseca on the bench. They have won 5 of their last 6 league matches. A fine run of form that has seen them move up to 4th place in the table. Having just beaten AJ Auxerre at the Stade de l'Abbé-Deschamps (1-3), Lyon are full of confidence ahead of their trip to Old Trafford.

Up to $1500 to bet on Manchester United - Lyon! 

Limited Offer. Currently at BetMGM

Manchester United against Lyon Lineups: Starting 11

Manchester United

Formation : 3 - 4 - 3

24
A. Onana
3
N. Mazraoui
5
H. Maguire
15
L. Yoro
20
D. Dalot
25
M. Ugarte
18
Casemiro
13
P. Dorgu
17
A. Garnacho
9
R. Hojlund
8
B. Fernandes
32
T. Almada
69
G. Mikautadze
18
R. Cherki
7
J. Veretout
4
P. Akouokou
8
C. Tolisso
3
N. Tagliafico
19
M. Niakhate
22
C. Mata
98
A. Maitland-Niles
23
L. Perri

Formation : 4 - 3 - 3

Lyon

Missing players

Manchester United
Manchester United
Defender

J. Evans

L. Martinez

Midfielder

A. Diallo

Lyon
Lyon
Midfielder

E. Nuamah

Manchester United & Lyon Squad Analysis

Manchester United will have to make do with a number of absentees for this second leg of their Europa League quarter-final. Ruben Amorim will be without Matthijs de Ligt, Lisandro Martinez, Jonny Evans, Amad Diallo and Joshua Zirkzee. Far from being blameless in the 2 goals he conceded in the first leg, André Onana did not play last weekend. It remains to be seen whether he will regain his starting place for this second leg. Bruno Fernandes will be one of the players to watch during this match. He boasts 16 goals and 18 assists in all competitions. He also provided an assist last week at Groupama Stadium.

Rayan Cherki is the man in great form in the Lyon ranks.

As for Lyon, Ernest Nuamah is absent. On the good news front, Paulo Fonseca should see Malick Fofana return to the squad. The Rhône-Alpes club will be able to count on several players in fine form. Corentin Tolisso is one of them. The French midfielder is back at the top of his game this season. And what about Rayan Cherki's performance? Scorer of the equalising goal in the first leg, the young Rhône-Alpes talent has 11 goals and 18 assists to his name in all competitions. Georges Mikautadze is another player to keep an eye on. He has been decisive in 5 of Les Gones' last 6 matches.

Most goals and assists

CD Huachipato Manchester United
CD Huachipato Lyon
Top Goalscorer
Portugal B. Fernandes (15 Goals)
Top Goalscorer
France A. Lacazette (17 Goals)
Best assists
Portugal B. Fernandes (15 Assists)
Best assists
France R. Cherki (17 Assists)

Manchester United - Lyon Key Points

  1. This season, in all competitions, Manuel Ugarte has picked up an average of 0.49 cards per 90 minutes.
  2. In all competitions, per 90 minutes, Manuel Ugarte averages 2.24 fouls per 90 minutes.
  3. In the Europa League, Manuel Ugarte averages 2.29 fouls per 90 minutes.
  4. Manuel Ugarte has been booked in three of his last five appearances for club and country.
Up to $1500 to bet on Manchester United - Lyon! 

Limited Offer. Currently at BetMGM

Our Manchester United vs Lyon Prediction

Frequent fouler Manuel Ugarte has become quite a useful player for Man United this season. His high-intensity presence can be helpful for the Red Devils, but he's certainly no stanger to getting booked, that's for sure. On average, he gets booked a little less often than once every other game.

 Frankly, Ugarte should not be available at such generous odds to go in the book. Odds of +280 should definitely be taken by those looking for value. Our Man United vs Lyon Pick: Manuel Ugarte to Get a Card.

Prediction:

 

Manuel Ugarte to Get a Card

+280
$1500 offered for betting!

Manchester United vs Lyon - Other Interesting Picks

Kobbie Mainoo to Get a Card

Odds +290
Kobbie Mainoo is another player who looks a little generously priced to go in the book on Thursday evening. The midfielder has had his season hindered by injury, but he's still managed to pick up seven yellows in all competitions, averaging 0.38 cards per 90 minutes. He came on to be booked almost instantly in the first leg and having recently regained full fitness, his energy in midfield could be key, so don't be surprised if he starts here. If he does start, don't be surprised if he gets himself in trouble.
$1500 offered for betting!

Don't miss out on a your rewards for the Manchester United vs Lyon matchup.

BetMGM Rewards

Looking to bet on Manchester United vs Lyon? For this Europa League matchup, BetMGM is offering rewards for every dollar you spend on match wagers. Win or lose, your wager goes further with BetMGM rewards. 

Signing up for BetMGM couldn't be easier, click here to get started today!

Rewards for the Manchester United vs Lyon match!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Manchester United vs Lyon Picks
Up to $1500 to bet on Manchester United - Lyon! 

Limited Offer. Currently at BetMGM