Lorenzo Musetti vs David Goffin Prediction & Picks - ATP US Open

ATP - ATP US Open

ATP 10 Italy
Lorenzo Musetti
8/28/25 11:00
ATP 80 Belgium
David Goffin

Prediction:

 

David Goffin +4.5 Games

+200
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 by Lou Aguila in ATP US Open Picks

Lorenzo Musetti of Italy eyes a place in the third round of the 2025 US Open Championship on Thursday, when he squares off with ATP veteran David Goffin of Belgium in the second round in Flushing Meadows, New York.

Musetti, a two-time Grand Slam semifinalist, will be trying to reach the third round of the US Open for the third time in his career after making it to the round of 32 in 2022 and 2024. Known for being a clay-court expert, the Italian needed 2 hours and 32 minutes to beat the big-serving Giovanni Mpetshi Perricard of France 6-7(3) 6-3 6-4 6-4. Musetti held 100 percent of his serves by winning 59 points behind the first serves and adding 28 points behind his second services. Moreover, he also shattered Perricard’s spirit by breaking his serve three times in the match. The win served as a confidence-booster for Musetti, who had lost four of his last six matches following his semifinal defeat to Carlos Alcaraz in the semifinal of the French Open.

Goffin also survived a grueling four-set tussle with Frenchman Quentin Halys 6-7(2) 6-4 6-3 7-5 to book his spot in the second round of the 2025 US Open. Goffin yielded six service breaks to Halys, but he also got back three more breakpoint conversions on 62 return points to seize the edge in the match. The Belgian is trying to go beyond the fourth round of the 2025 US Open for the first time in his career after coming up a win short of a quarterfinals stint four times. Goffin has been in the round of 16 of the US Open in 2017, 2018, 2019, and 2020.

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Lorenzo Musetti vs David Goffin Form

Lorenzo Musetti and David Goffin Latest Matches

Lorenzo Musetti Latest matches
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 26, 2025 - ATP US Open

Lorenzo Musetti
3 :  1
Giovanni Mpetshi Perricard

Aug 9, 2025 - ATP Cincinnati Open

Benjamin Bonzi
2 :  1
Lorenzo Musetti

Jul 31, 2025 - ATP Toronto

Lorenzo Musetti
1 :  2
Alex Michelsen

Jul 29, 2025 - ATP Toronto

Lorenzo Musetti
2 :  0
James Duckworth

Jul 22, 2025 - ATP Washington Citi Open

Cameron Norrie
2 :  1
Lorenzo Musetti

Jul 1, 2025 - ATP Wimbledon Championships

Nikoloz Basilashvili
3 :  1
Lorenzo Musetti
David Goffin Latest matches
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Aug 26, 2025 - ATP US Open

Quentin Halys
1 :  3
David Goffin

Aug 17, 2025 - ATP Winston-Salem Open

David Goffin
0 :  2
Pedro Martinez

Aug 7, 2025 - ATP Cincinnati Open

Sebastian Baez
2 :  0
David Goffin

Jul 28, 2025 - ATP Toronto

Mackenzie Mcdonald
2 :  0
David Goffin

Jul 22, 2025 - ATP Washington Citi Open

David Goffin
0 :  2
Yunchaokete Bu

Jul 16, 2025 - ATP Swiss Open Gstaad

Juan Manuel Cerundolo
2 :  1
David Goffin

Lorenzo Musetti against David Goffin : Head to Head (H2H)

Lorenzo Musetti

75 %

David Goffin

25 %

Oct 7, 2024 - ATP Shanghai Masters

Lorenzo Musetti
1 :  2
David Goffin

May 17, 2024 - Turin, Italy

Lorenzo Musetti
2 :  0
David Goffin

Aug 30, 2022 - ATP US Open

David Goffin
2 :  3
Lorenzo Musetti

May 31, 2021 - ATP French Open

Lorenzo Musetti
3 :  0
David Goffin
Compare Lorenzo Musetti and David Goffin with our comparison tool.

Lorenzo Musetti - David Goffin Key Points

  1. David Goffin defeated Quentin Halys 6-7(2) 6-4 6-3 7-5 in the first round of the 2025 US Open.
  2. David Goffin has reached the round of 16 of the US Open four times.
  3. Lorenzo Musetti defeated Giovanni Mpetshi Perricard 6-7(3) 6-3 6-4 6-4 in the first round of the 2025 US Open.
  4. Lorenzo Musetti is 3-1 head-to-head against David Goffin.
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Our Lorenzo Musetti vs David Goffin Prediction

I am taking David Goffin to cover +4.5 Games against Lorenzo Musetti in this intriguing second-round battle in Flushing Meadows. Musetti might be 3-1 in their head-to-head series, but two of those wins came on clay courts where Musetti is expected to have a significant edge. Musetti’s other win over Goffin happened in a hard-court match in the first round of the 2022 US Open. Musetti had to dig deep to overcome Goffin in a thrilling five-setter 3-6 7-5 6-4 3-6 7-6(9). Goffin ended his winless run against the Italian by hacking out 1-6 7-6(6) 6-2 win in the second round of the 2024 Shanghai Masters.

Goffin might be turning 35 years old this December, but he’s bringing his vast experience and an impressive hard-court win rate (61 percent) into his fifth career clash with Musetti. Musetti is no doubt a world-class talent and a formidable player, especially on clay, but his sketchy record in hard-court Grand Slams, along with a mediocre 52 percent win rate on the surface, makes him vulnerable even against a vet like Goffin.

Our betting prediction for David Goffin vs. Lorenzo Musetti: David Goffin +4.5 Games

Prediction:

 

David Goffin +4.5 Games

+200
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Lorenzo Musetti vs David Goffin Picks
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