Karen Khachanov vs Alexander Blockx Prediction & Picks - ATP US Open

Prediction published on 9/9/26, 12:15 AM  by Lou Aguila | Modified on 9/9/26 at 12:19 AM in ATP US Open Picks

Alexander Blockx shoots for his place in the semifinal of the 2026 US Open against Karen Khachanov on Wednesday.

Blockx is an attractive underdog pick at +136.

Current Form:

Karen Khachanov hacked out a five-set win over Learner Tien, 7-5, 4-6, 6-7, 6-1, 6-4 to clinch his spot in the quarterfinals of the 2026 US Open. Khachanov, who had not won a single hard-court match before this tournament, has taken out a bunch of prominent names in this tournament. This includes No.3 seed Felix-Auger Aliassime and No.14 seed Tien.

Alexander Blockx punched his ticket to the quarterfinals with another four-set win over Francisco Cerundolo, 6-3, 4-6, 7-5, 7-5. After sweeping Tomas Barrios Vera, 6-3, 6-4, 6-2, in the first round, Blockx has won his last three matches in four sets. He also defeated Marco Trungelliti 6-3, 6-2, 3-6, 6-1, and Flavio Cobolli 6-7, 6-3, 6-0, 6-3.

The Matchup: Khachanov and Blockx will play against each other for the first time. The veteran Khachanov opened the betting lines as the favorite, but Blockx has no doubt made himself a high-value target for big-swing bettors.