Jacksonville Jaguars vs Indianapolis Colts Prediction & Picks - NFL

USA - NFL

Jacksonville Jaguars
11/1/26 13:00
Indianapolis Colts

Prediction:

 

Jaguars -10.5

−102
$350 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Carlos Zabala in NFL Picks

The Colts have a 2-5 record after losing their last three games, all by a margin of no more than six points. They close out October against the Vikings with a 10-16 loss, and Indianapolis is facing changes that may not inspire immediate optimism, having traded Buckner and Nelson and fired longtime general manager Chris Ballard. This is how they will approach Sunday at EverBank Stadium to face the Jaguars, who have a 3-1-0 record.

This season, Daniel Jones has more interceptions than touchdown passes. Looking at the big picture, these Colts have lost 12 of their last 14 games. The Colts are hoping that rushing Jonathan Taylor can pull them out of this slump; despite everything, he has had a decent season, with 140 carries for 8 touchdowns, averaging 4.19 points per carry.

After spending two weeks at their alternate home in London, the Jaguars defeated the Eagles by two points but lost by three to the Texans to close out the month. That loss included a close game with Lawrence completing 24 of 41 passes and throwing for 4 touchdowns.

Jacksonville Jaguars vs Indianapolis Colts Form

Table

Teams Pts P W L
9 Jacksonville Jaguars
0.667 6 4 2
26 Indianapolis Colts
0.286 7 2 5

Jacksonville Jaguars and Indianapolis Colts Latest Matches

Jacksonville Jaguars
Jacksonville Jaguars Latest matches
W L W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Oct 18, 2026 - NFL

Jacksonville Jaguars
31 :  34
Houston Texans

Oct 11, 2026 - NFL

Jacksonville Jaguars
19 :  17
Philadelphia Eagles

Oct 4, 2026 - NFL

Cincinnati Bengals
17 :  22
Jacksonville Jaguars

Sep 27, 2026 - NFL

Jacksonville Jaguars
35 :  6
New England Patriots

Sep 20, 2026 - NFL

Denver Broncos
20 :  13
Jacksonville Jaguars

Sep 13, 2026 - NFL

Jacksonville Jaguars
34 :  10
Cleveland Browns
W L W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Oct 18, 2026 - NFL

Jacksonville Jaguars
31 :  34
Houston Texans

Oct 11, 2026 - NFL

Jacksonville Jaguars
19 :  17
Philadelphia Eagles

Sep 27, 2026 - NFL

Jacksonville Jaguars
35 :  6
New England Patriots

Sep 13, 2026 - NFL

Jacksonville Jaguars
34 :  10
Cleveland Browns

Jan 11, 2026 - NFL

Jacksonville Jaguars
24 :  27
Buffalo Bills

Jan 4, 2026 - NFL

Jacksonville Jaguars
41 :  7
Tennessee Titans
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Oct 4, 2026 - NFL

Cincinnati Bengals
17 :  22
Jacksonville Jaguars

Sep 20, 2026 - NFL

Denver Broncos
20 :  13
Jacksonville Jaguars

Dec 28, 2025 - NFL

Indianapolis Colts
17 :  23
Jacksonville Jaguars

Dec 21, 2025 - NFL

Denver Broncos
20 :  34
Jacksonville Jaguars

Nov 30, 2025 - NFL

Tennessee Titans
3 :  25
Jacksonville Jaguars

Nov 23, 2025 - NFL

Arizona Cardinals
24 :  27
Jacksonville Jaguars
Indianapolis Colts
Indianapolis Colts Latest matches
L W W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Oct 25, 2026 - NFL

Minnesota Vikings
16 :  10
Indianapolis Colts

Oct 18, 2026 - NFL

Indianapolis Colts
20 :  26
Tennessee Titans

Oct 11, 2026 - NFL

Pittsburgh Steelers
34 :  22
Indianapolis Colts

Oct 4, 2026 - NFL

Washington Commanders
13 :  30
Indianapolis Colts

Sep 27, 2026 - NFL

Indianapolis Colts
19 :  17
Houston Texans

Sep 20, 2026 - NFL

Kansas City Chiefs
33 :  30
Indianapolis Colts
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Oct 18, 2026 - NFL

Indianapolis Colts
20 :  26
Tennessee Titans

Sep 27, 2026 - NFL

Indianapolis Colts
19 :  17
Houston Texans

Sep 13, 2026 - NFL

Indianapolis Colts
23 :  41
Baltimore Ravens

Dec 28, 2025 - NFL

Indianapolis Colts
17 :  23
Jacksonville Jaguars

Dec 22, 2025 - NFL

Indianapolis Colts
27 :  48
San Francisco 49ers

Nov 30, 2025 - NFL

Indianapolis Colts
16 :  20
Houston Texans
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Oct 25, 2026 - NFL

Minnesota Vikings
16 :  10
Indianapolis Colts

Oct 11, 2026 - NFL

Pittsburgh Steelers
34 :  22
Indianapolis Colts

Oct 4, 2026 - NFL

Washington Commanders
13 :  30
Indianapolis Colts

Sep 20, 2026 - NFL

Kansas City Chiefs
33 :  30
Indianapolis Colts

Jan 4, 2026 - NFL

Houston Texans
38 :  30
Indianapolis Colts

Dec 14, 2025 - NFL

Seattle Seahawks
18 :  16
Indianapolis Colts

Jacksonville Jaguars against Indianapolis Colts : Head to Head (H2H)

Jacksonville Jaguars

75 %

Indianapolis Colts

25 %

Dec 28, 2025 - NFL

Indianapolis Colts
17 :  23
Jacksonville Jaguars

Dec 7, 2025 - NFL

Jacksonville Jaguars
36 :  19
Indianapolis Colts

Jan 5, 2025 - NFL

Indianapolis Colts
26 :  23
Jacksonville Jaguars

Oct 6, 2024 - NFL

Jacksonville Jaguars
37 :  34
Indianapolis Colts
Jacksonville Jaguars vs Indianapolis Colts Picks

Jacksonville Jaguars - Indianapolis Colts Key Points

  1. Jaguars rank fourth in the NFL in 3rd down conversions with 47.9
  2. Jaguars defense allows the fewest rushing yards per game this season
  3. Jaguars have won 5 of their last 6 games against the Colts
  4. Jaguars wide receiver Parker Washington has scored 4 touchdowns this season

Our Jacksonville Jaguars vs Indianapolis Colts Prediction

While the Colts appear to be dismantling their roster, the Jaguars, both in England and upon their return to the USA, continue to look like a highly competitive team with few weaknesses.

Jacksonville also had a long bye-week, so they will start a very busy November with fresh legs, ready to battle this wounded divisional rival whom they will face twice this season.

Our prediction for Jaguars vs Colts is: Jaguars -10.5.

Prediction:

 

Jaguars -10.5

−102
$350 offered for betting!

Welcome Bonus for the Jacksonville Jaguars vs Indianapolis Colts match!

FanDuel Bonus $350

FanDuel is offering some great promos for the beginning of football season, including their welcome offer of $350, which can be activated for this Jacksonville Jaguars vs Indianapolis Colts match! Simply sign up and place a first bet of at least $5. You can do this during your first 7 days with FanDuel, earning a total of $350 in bet reset tokens!

Remember, the offer is only open to new sign-ups!

$350 in bonus bets for Jacksonville Jaguars vs Indianapolis Colts!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.