Houston Texans vs Jacksonville Jaguars Prediction & Picks - NFL

USA - NFL

Houston Texans
9/21/25 13:00
Jacksonville Jaguars

Prediction:

 

Under 43.5

-105
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 by Erik Gibbs in NFL Picks

The Jacksonville Jaguars meet the Houston Texans in an early divisional matchup that could highlight contrasting trajectories. Jacksonville comes into the game at 1–1, having opened their campaign with a comfortable win before dropping a narrow, high-scoring battle against a tougher opponent. Their defense impressed in the opener, holding the opposing attack to minimal points, while their offense produced balance through both the passing and rushing games.

The second outing was more challenging, with their defense conceding more, but the Jaguars still moved the ball effectively and kept themselves competitive until the final drive. Their ability to adapt to different styles of play suggests promise. Houston, on the other hand, has had a tough beginning at 0–2. They lost their opener in a low-scoring contest that exposed offensive inefficiency, followed by a home defeat where they narrowly missed out despite holding a late lead.

The Texans' defense has worked hard, but the unit has often been forced into extended stretches on the field due to offensive stagnation. As a result, they find themselves chasing in the standings, desperate for a turnaround.

Houston Texans vs Jacksonville Jaguars Form

Table

Teams % P W D L
17
Jacksonville Jaguars
Jacksonville Jaguars
0.5 2 1 0 1
31
Houston Texans
Houston Texans
0 2 0 0 2

Houston Texans and Jacksonville Jaguars Latest Matches

Houston Texans
Houston Texans Latest matches
L W W L L L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Sep 15, 2025 - NFL

Tampa Bay Buccaneers
20 :  19
Houston Texans

Sep 7, 2025 - NFL

Houston Texans
9 :  14
Los Angeles Rams

Jan 18, 2025 - NFL

Houston Texans
14 :  23
Kansas City Chiefs

Jan 11, 2025 - NFL

Los Angeles Chargers
12 :  32
Houston Texans

Jan 5, 2025 - NFL

Houston Texans
23 :  14
Tennessee Titans

Dec 25, 2024 - NFL

Baltimore Ravens
31 :  2
Houston Texans
L L W L W L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Sep 15, 2025 - NFL

Tampa Bay Buccaneers
20 :  19
Houston Texans

Jan 11, 2025 - NFL

Los Angeles Chargers
12 :  32
Houston Texans

Dec 25, 2024 - NFL

Baltimore Ravens
31 :  2
Houston Texans

Dec 15, 2024 - NFL

Miami Dolphins
12 :  20
Houston Texans

Nov 24, 2024 - NFL

Tennessee Titans
32 :  27
Houston Texans

Nov 10, 2024 - NFL

Detroit Lions
26 :  23
Houston Texans
W W L W L L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Sep 7, 2025 - NFL

Houston Texans
9 :  14
Los Angeles Rams

Jan 18, 2025 - NFL

Houston Texans
14 :  23
Kansas City Chiefs

Jan 5, 2025 - NFL

Houston Texans
23 :  14
Tennessee Titans

Dec 21, 2024 - NFL

Houston Texans
19 :  27
Kansas City Chiefs

Dec 1, 2024 - NFL

Houston Texans
23 :  20
Jacksonville Jaguars

Nov 18, 2024 - NFL

Houston Texans
34 :  10
Dallas Cowboys
Jacksonville Jaguars
Jacksonville Jaguars Latest matches
L L W L W L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Sep 14, 2025 - NFL

Jacksonville Jaguars
27 :  31
Cincinnati Bengals

Sep 7, 2025 - NFL

Carolina Panthers
10 :  26
Jacksonville Jaguars

Jan 5, 2025 - NFL

Jacksonville Jaguars
23 :  26
Indianapolis Colts

Dec 29, 2024 - NFL

Tennessee Titans
13 :  20
Jacksonville Jaguars

Dec 22, 2024 - NFL

Jacksonville Jaguars
14 :  19
Las Vegas Raiders

Dec 15, 2024 - NFL

New York Jets
32 :  25
Jacksonville Jaguars
L L L L W W
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Sep 7, 2025 - NFL

Carolina Panthers
10 :  26
Jacksonville Jaguars

Dec 29, 2024 - NFL

Tennessee Titans
13 :  20
Jacksonville Jaguars

Dec 15, 2024 - NFL

New York Jets
32 :  25
Jacksonville Jaguars

Dec 1, 2024 - NFL

Houston Texans
23 :  20
Jacksonville Jaguars

Nov 10, 2024 - NFL

Minnesota Vikings
12 :  7
Jacksonville Jaguars

Oct 27, 2024 - NFL

Green Bay Packers
30 :  27
Jacksonville Jaguars
L L W L L L
Victories

1/6 (17%)

Draw

0/6 (0%)

Defeats

5/6 (83%)

Sep 14, 2025 - NFL

Jacksonville Jaguars
27 :  31
Cincinnati Bengals

Jan 5, 2025 - NFL

Jacksonville Jaguars
23 :  26
Indianapolis Colts

Dec 22, 2024 - NFL

Jacksonville Jaguars
14 :  19
Las Vegas Raiders

Dec 8, 2024 - NFL

Jacksonville Jaguars
10 :  6
Tennessee Titans

Nov 17, 2024 - NFL

Jacksonville Jaguars
6 :  52
Detroit Lions

Nov 3, 2024 - NFL

Jacksonville Jaguars
23 :  28
Philadelphia Eagles

Houston Texans against Jacksonville Jaguars : Head to Head (H2H)

Houston Texans

83 %

Draw

0 %

Jacksonville Jaguars

17 %

Dec 1, 2024 - NFL

Houston Texans
23 :  20
Jacksonville Jaguars

Sep 29, 2024 - NFL

Jacksonville Jaguars
20 :  24
Houston Texans

Nov 26, 2023 - NFL

Jacksonville Jaguars
24 :  21
Houston Texans

Dec 19, 2021 - NFL

Houston Texans
30 :  16
Jacksonville Jaguars

Sep 15, 2019 - NFL

Jacksonville Jaguars
12 :  13
Houston Texans

Dec 30, 2018 - NFL

Jacksonville Jaguars
3 :  20
Houston Texans

Houston Texans - Jacksonville Jaguars Key Points

  1. The Over is 1-7 in the Jaguars’ last 8 games at EverBank Stadium after a loss
  2. The Jaguars are 4-0 ATS in their last 4 games vs. AFC South teams
  3. The Texans are 0-10 ATS in their last 10 games when playing with a rest disadvantage
  4. The home team is 5-0 in the Jaguars’ last five games

Our Houston Texans vs Jacksonville Jaguars Prediction

Jacksonville looks more settled. Their quarterback has already thrown multiple touchdowns in each of the first two games, showing composure in big moments even if turnovers remain an occasional issue. His ability to keep drives alive has been complemented by their featured running back, who has accumulated over 200 yards at an excellent per-carry average. This ground threat gives Jacksonville valuable balance and makes their passing attack harder to predict.

Houston's rookie quarterback has displayed glimpses of talent, moving the ball between the 20s with solid yardage totals, but his ability to finish drives has been limited. He has one touchdown and one interception to date, and the lack of an established rushing attack has left him carrying too much of the offensive burden. The Texans' wideouts have yet to make a significant impact, leaving their rookie signal caller with fewer reliable targets.

Defensively, Houston struggles with giving up big plays, while Jacksonville's top weapons are capable of producing them. On paper, the Jaguars' established balance and more productive individuals give them a clear edge. Our prediction for Jacksonville Jaguars vs. Houston Texans: Under 43.5 points.

Prediction:

 

Under 43.5

-105
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Houston Texans vs Jacksonville Jaguars Picks