Milwaukee Bucks vs Detroit Pistons Prediction & Picks - NBA

USA - NBA

Milwaukee Bucks
11/22/25 20:00
Detroit Pistons

Prediction:

 

Pistons (-9.5) cover the spread

-106
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 by Paul Tamayo in NBA Picks

The Detroit Pistons (13-2) visit the Milwaukee Bucks (8-8) in an NBA 2025-26 game on Saturday, November 22, at Fiserv Forum.

Detroit is in the middle of a dream start. The Pistons sit atop the Eastern Conference with a 13-2 record, while riding an 11-game winning streak into this matchup. They're coming off a 120-112 win over the Atlanta Hawks, starting a four-game road trip on a high note.

All five Pistons starters scored in double digits in the win against the Hawks, with Cade Cunningham and Jalen Duren tallying 25 and 24 markers, respectively. 

Along with their offense, the Pistons have also excelled defensively. Through the first 15 games of the season, they rank 2nd in the league in defensive rating (110.6).

As for the Bucks, they return to action after a draining 123-114 overtime loss to the Philadelphia 76ers on Thursday. They were outscored 17-8 in the extra period and simply ran out of gas as Sixers star Tyrese Maxey torched them for a career-high 54 points.

Things aren't going to be easier for the Bucks moving forward, as Giannis Antetokounmpo remains sidelined due to a groin injury. For the Pistons, Jaden Ivey and Tobias Harris are listed out.

Milwaukee Bucks vs Detroit Pistons Form

Table

Teams % P W L Series
2
Detroit Pistons
Detroit Pistons
0.744 39 29 10 1
22
Milwaukee Bucks
Milwaukee Bucks
0.415 41 17 24

Milwaukee Bucks and Detroit Pistons Latest Matches

Milwaukee Bucks
Milwaukee Bucks Latest matches
W L W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 20, 2025 - NBA

Milwaukee Bucks
114 :  123
Philadelphia 76ers

Nov 17, 2025 - NBA

Cleveland Cavaliers
118 :  106
Milwaukee Bucks

Nov 15, 2025 - NBA

Milwaukee Bucks
95 :  119
Los Angeles Lakers

Nov 14, 2025 - NBA

Milwaukee Bucks
147 :  134
Charlotte Hornets

Nov 12, 2025 - NBA

Charlotte Hornets
111 :  100
Milwaukee Bucks

Nov 10, 2025 - NBA

Dallas Mavericks
114 :  116
Milwaukee Bucks
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 20, 2025 - NBA

Milwaukee Bucks
114 :  123
Philadelphia 76ers

Nov 15, 2025 - NBA

Milwaukee Bucks
95 :  119
Los Angeles Lakers

Nov 14, 2025 - NBA

Milwaukee Bucks
147 :  134
Charlotte Hornets

Nov 9, 2025 - NBA

Milwaukee Bucks
115 :  122
Houston Rockets

Nov 7, 2025 - NBA

Milwaukee Bucks
126 :  110
Chicago Bulls

Nov 1, 2025 - NBA

Milwaukee Bucks
133 :  135
Sacramento Kings
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 17, 2025 - NBA

Cleveland Cavaliers
118 :  106
Milwaukee Bucks

Nov 12, 2025 - NBA

Charlotte Hornets
111 :  100
Milwaukee Bucks

Nov 10, 2025 - NBA

Dallas Mavericks
114 :  116
Milwaukee Bucks

Nov 4, 2025 - NBA

Toronto Raptors
128 :  100
Milwaukee Bucks

Nov 3, 2025 - NBA

Indiana Pacers
115 :  117
Milwaukee Bucks

Oct 26, 2025 - NBA

Cleveland Cavaliers
118 :  113
Milwaukee Bucks
Detroit Pistons
Detroit Pistons Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Nov 18, 2025 - NBA

Atlanta Hawks
112 :  120
Detroit Pistons

Nov 17, 2025 - NBA

Detroit Pistons
127 :  112
Indiana Pacers

Nov 14, 2025 - NBA

Detroit Pistons
114 :  105
Philadelphia 76ers

Nov 12, 2025 - NBA

Detroit Pistons
124 :  113
Chicago Bulls

Nov 10, 2025 - NBA

Detroit Pistons
137 :  135
Washington Wizards

Nov 9, 2025 - NBA

Philadelphia 76ers
108 :  111
Detroit Pistons
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Nov 17, 2025 - NBA

Detroit Pistons
127 :  112
Indiana Pacers

Nov 14, 2025 - NBA

Detroit Pistons
114 :  105
Philadelphia 76ers

Nov 12, 2025 - NBA

Detroit Pistons
124 :  113
Chicago Bulls

Nov 10, 2025 - NBA

Detroit Pistons
137 :  135
Washington Wizards

Nov 5, 2025 - NBA

Detroit Pistons
114 :  103
Utah Jazz

Nov 1, 2025 - NBA

Detroit Pistons
122 :  110
Dallas Mavericks
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Nov 18, 2025 - NBA

Atlanta Hawks
112 :  120
Detroit Pistons

Nov 9, 2025 - NBA

Philadelphia 76ers
108 :  111
Detroit Pistons

Nov 7, 2025 - NBA

Brooklyn Nets
107 :  125
Detroit Pistons

Nov 3, 2025 - NBA

Memphis Grizzlies
106 :  114
Detroit Pistons

Oct 24, 2025 - NBA

Houston Rockets
111 :  115
Detroit Pistons

Oct 22, 2025 - NBA

Chicago Bulls
115 :  111
Detroit Pistons

Milwaukee Bucks against Detroit Pistons : Head to Head (H2H)

Milwaukee Bucks

100 %

Detroit Pistons

0 %

Apr 13, 2025 - NBA

Milwaukee Bucks
140 :  133
Detroit Pistons

Apr 11, 2025 - NBA

Detroit Pistons
119 :  125
Milwaukee Bucks

Dec 3, 2024 - NBA

Detroit Pistons
107 :  128
Milwaukee Bucks

Nov 13, 2024 - NBA

Milwaukee Bucks
127 :  120
Detroit Pistons

Jan 22, 2024 - NBA

Detroit Pistons
113 :  122
Milwaukee Bucks

Jan 20, 2024 - NBA

Detroit Pistons
135 :  141
Milwaukee Bucks

Players list

Milwaukee Bucks
Milwaukee Bucks
M. Turner Goalkeeper

R. Rollins

A. Green

Forward

B. Portis

K. Kuzma

Detroit Pistons
Detroit Pistons
J. Duren A. Thompson Goalkeeper

C. Cunningham

Forward

T. Harris

D. Robinson

Substitutes

Milwaukee Bucks
Milwaukee Bucks
A. Jackson Jr. A. Coffey J. Sims G. Trent Jr. Goalkeeper

G. Harris

C. Anthony

M. Sears

Forward

T. Antetokounmpo

P. Nance

Detroit Pistons
Detroit Pistons
I. Stewart J. Green Goalkeeper

D. Jenkins

J. Ivey

C. Lanier

C. LeVert

Forward

P. Reed

R. Holland

Milwaukee Bucks - Detroit Pistons Key Points

  1. The Bucks are coming off a 123-114 overtime loss to the Philadelphia 76ers.
  2. The Pistons are coming off a 120-112 win over the Atlanta Hawks.
  3. The Bucks will miss the services of Giannis Antetokounmpo, Taurean Prince, and Kevin Porter Jr.
  4. The Pistons will miss the services of Jaden Ivey and Tobias Harris.

Our Milwaukee Bucks vs Detroit Pistons Prediction

With Milwaukee shorthanded and struggling late in games, this game against Detroit sets up another difficult challenge for the Bucks. They have to dig deeper in the absence of injured superstar forward Giannis Antetokounmpo.

Meanwhile, the Pistons come in fiery form, having won their last 11 games. Expect Cade Cunningham, Jalen Duren, and the rest of the Pistons to dominate this Giannis-less Bucks. Our prediction for the Milwaukee Bucks vs Detroit Pistons match is: Pistons (-9.5) cover the spread.

Prediction:

 

Pistons (-9.5) cover the spread

-106
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Milwaukee Bucks vs Detroit Pistons Picks