Detroit Pistons vs Milwaukee Bucks Prediction & Picks - NBA

USA - NBA

Detroit Pistons
11/22/25 20:00
Milwaukee Bucks

Prediction:

 

Pistons (-9.5) cover the spread

-106
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 by Paul Tamayo in NBA Picks

The Detroit Pistons (13-2) visit the Milwaukee Bucks (8-8) in an NBA 2025-26 game on Saturday, November 22, at Fiserv Forum.

Detroit is in the middle of a dream start. The Pistons sit atop the Eastern Conference with a 13-2 record, while riding an 11-game winning streak into this matchup. They're coming off a 120-112 win over the Atlanta Hawks, starting a four-game road trip on a high note.

All five Pistons starters scored in double digits in the win against the Hawks, with Cade Cunningham and Jalen Duren tallying 25 and 24 markers, respectively. 

Along with their offense, the Pistons have also excelled defensively. Through the first 15 games of the season, they rank 2nd in the league in defensive rating (110.6).

As for the Bucks, they return to action after a draining 123-114 overtime loss to the Philadelphia 76ers on Thursday. They were outscored 17-8 in the extra period and simply ran out of gas as Sixers star Tyrese Maxey torched them for a career-high 54 points.

Things aren't going to be easier for the Bucks moving forward, as Giannis Antetokounmpo remains sidelined due to a groin injury. For the Pistons, Jaden Ivey and Tobias Harris are listed out.

Detroit Pistons vs Milwaukee Bucks Form

Table

Teams % P W L Series
1
Detroit Pistons
Detroit Pistons
0.867 15 13 2 11
10
Milwaukee Bucks
Milwaukee Bucks
0.5 16 8 8 -3

Detroit Pistons and Milwaukee Bucks Latest Matches

Detroit Pistons
Detroit Pistons Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Nov 18, 2025 - NBA

Detroit Pistons
120 :  112
Atlanta Hawks

Nov 17, 2025 - NBA

Indiana Pacers
112 :  127
Detroit Pistons

Nov 14, 2025 - NBA

Philadelphia 76ers
105 :  114
Detroit Pistons

Nov 12, 2025 - NBA

Chicago Bulls
113 :  124
Detroit Pistons

Nov 10, 2025 - NBA

Washington Wizards
135 :  137
Detroit Pistons

Nov 9, 2025 - NBA

Detroit Pistons
111 :  108
Philadelphia 76ers
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Nov 17, 2025 - NBA

Indiana Pacers
112 :  127
Detroit Pistons

Nov 14, 2025 - NBA

Philadelphia 76ers
105 :  114
Detroit Pistons

Nov 12, 2025 - NBA

Chicago Bulls
113 :  124
Detroit Pistons

Nov 10, 2025 - NBA

Washington Wizards
135 :  137
Detroit Pistons

Nov 5, 2025 - NBA

Utah Jazz
103 :  114
Detroit Pistons

Nov 1, 2025 - NBA

Dallas Mavericks
110 :  122
Detroit Pistons
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Nov 18, 2025 - NBA

Detroit Pistons
120 :  112
Atlanta Hawks

Nov 9, 2025 - NBA

Detroit Pistons
111 :  108
Philadelphia 76ers

Nov 7, 2025 - NBA

Detroit Pistons
125 :  107
Brooklyn Nets

Nov 3, 2025 - NBA

Detroit Pistons
114 :  106
Memphis Grizzlies

Oct 24, 2025 - NBA

Detroit Pistons
115 :  111
Houston Rockets

Oct 22, 2025 - NBA

Detroit Pistons
111 :  115
Chicago Bulls
Milwaukee Bucks
Milwaukee Bucks Latest matches
W L W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 20, 2025 - NBA

Philadelphia 76ers
123 :  114
Milwaukee Bucks

Nov 17, 2025 - NBA

Milwaukee Bucks
106 :  118
Cleveland Cavaliers

Nov 15, 2025 - NBA

Los Angeles Lakers
119 :  95
Milwaukee Bucks

Nov 14, 2025 - NBA

Charlotte Hornets
134 :  147
Milwaukee Bucks

Nov 12, 2025 - NBA

Milwaukee Bucks
100 :  111
Charlotte Hornets

Nov 10, 2025 - NBA

Milwaukee Bucks
116 :  114
Dallas Mavericks
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 20, 2025 - NBA

Philadelphia 76ers
123 :  114
Milwaukee Bucks

Nov 15, 2025 - NBA

Los Angeles Lakers
119 :  95
Milwaukee Bucks

Nov 14, 2025 - NBA

Charlotte Hornets
134 :  147
Milwaukee Bucks

Nov 9, 2025 - NBA

Houston Rockets
122 :  115
Milwaukee Bucks

Nov 7, 2025 - NBA

Chicago Bulls
110 :  126
Milwaukee Bucks

Nov 1, 2025 - NBA

Sacramento Kings
135 :  133
Milwaukee Bucks
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 17, 2025 - NBA

Milwaukee Bucks
106 :  118
Cleveland Cavaliers

Nov 12, 2025 - NBA

Milwaukee Bucks
100 :  111
Charlotte Hornets

Nov 10, 2025 - NBA

Milwaukee Bucks
116 :  114
Dallas Mavericks

Nov 4, 2025 - NBA

Milwaukee Bucks
100 :  128
Toronto Raptors

Nov 3, 2025 - NBA

Milwaukee Bucks
117 :  115
Indiana Pacers

Oct 26, 2025 - NBA

Milwaukee Bucks
113 :  118
Cleveland Cavaliers

Detroit Pistons against Milwaukee Bucks : Head to Head (H2H)

Detroit Pistons

0 %

Milwaukee Bucks

100 %

Apr 13, 2025 - NBA

Detroit Pistons
133 :  140
Milwaukee Bucks

Apr 11, 2025 - NBA

Milwaukee Bucks
125 :  119
Detroit Pistons

Dec 3, 2024 - NBA

Milwaukee Bucks
128 :  107
Detroit Pistons

Nov 13, 2024 - NBA

Detroit Pistons
120 :  127
Milwaukee Bucks

Jan 22, 2024 - NBA

Milwaukee Bucks
122 :  113
Detroit Pistons

Jan 20, 2024 - NBA

Milwaukee Bucks
141 :  135
Detroit Pistons

Detroit Pistons - Milwaukee Bucks Key Points

  1. The Bucks are coming off a 123-114 overtime loss to the Philadelphia 76ers.
  2. The Pistons are coming off a 120-112 win over the Atlanta Hawks.
  3. The Bucks will miss the services of Giannis Antetokounmpo, Taurean Prince, and Kevin Porter Jr.
  4. The Pistons will miss the services of Jaden Ivey and Tobias Harris.

Our Detroit Pistons vs Milwaukee Bucks Prediction

With Milwaukee shorthanded and struggling late in games, this game against Detroit sets up another difficult challenge for the Bucks. They have to dig deeper in the absence of injured superstar forward Giannis Antetokounmpo.

Meanwhile, the Pistons come in fiery form, having won their last 11 games. Expect Cade Cunningham, Jalen Duren, and the rest of the Pistons to dominate this Giannis-less Bucks. Our prediction for the Milwaukee Bucks vs Detroit Pistons match is: Pistons (-9.5) cover the spread.

Prediction:

 

Pistons (-9.5) cover the spread

-106
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Detroit Pistons vs Milwaukee Bucks Picks