Arizona Cardinals vs Houston Texans Prediction & Picks - NFL

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Arizona Cardinals
12/14/25 13:00
Houston Texans

Prediction:

 

Cardinals (+9.5) to win

-111
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 by Simon Day in NFL Picks

The surging 8-5 Houston Texans host the 3-10 Arizona Cardinals on Sunday, knowing that a victory will move them a big step closer to securing a place in the AFC playoffs. 

After starting the campaign 0-3, things were looking bleak in Houston. However, a dramatic turnaround in form has seen them win eight of their last ten games, including victories over all three of their AFC South rivals. In reality, 10 wins should be enough to earn a postseason berth, so if the Texnas can win on Sunday, plus defeat the 2-11 Raiders next week, they will be virtually assured of their playoff place. 

In stark contrast to the Texans, Arizona started the season 2-0, but have subsequently fallen apart and are already eliminated from playoff contention. Last week's 17-45 thrashing at the hands of the Rams was the Cards' worst display of the campaign and huge offseason changes are needed if HC Jonathan Gannon wants to turn Arizona into 2026 playoff contenders. 

Arizona Cardinals vs Houston Texans Form

Table

Teams % P W D L
11
Houston Texans
Houston Texans
0.615 13 8 0 5
26
Arizona Cardinals
Arizona Cardinals
0.231 13 3 0 10

Arizona Cardinals and Houston Texans Latest Matches

Arizona Cardinals
Arizona Cardinals Latest matches
W L L L L L
Victories

1/6 (17%)

Draw

0/6 (0%)

Defeats

5/6 (83%)

Dec 7, 2025 - NFL

Los Angeles Rams
45 :  17
Arizona Cardinals

Nov 30, 2025 - NFL

Arizona Cardinals
17 :  20
Tampa Bay Buccaneers

Nov 23, 2025 - NFL

Jacksonville Jaguars
27 :  24
Arizona Cardinals

Nov 16, 2025 - NFL

San Francisco 49ers
41 :  22
Arizona Cardinals

Nov 9, 2025 - NFL

Arizona Cardinals
22 :  44
Seattle Seahawks

Nov 3, 2025 - NFL

Arizona Cardinals
27 :  17
Dallas Cowboys
L L L L L L
Victories

0/6 (0%)

Draw

0/6 (0%)

Defeats

6/6 (100%)

Dec 7, 2025 - NFL

Los Angeles Rams
45 :  17
Arizona Cardinals

Nov 23, 2025 - NFL

Jacksonville Jaguars
27 :  24
Arizona Cardinals

Nov 16, 2025 - NFL

San Francisco 49ers
41 :  22
Arizona Cardinals

Oct 19, 2025 - NFL

Green Bay Packers
27 :  23
Arizona Cardinals

Oct 5, 2025 - NFL

Tennessee Titans
22 :  21
Arizona Cardinals

Sep 25, 2025 - NFL

Seattle Seahawks
23 :  20
Arizona Cardinals
W L L W L L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Nov 30, 2025 - NFL

Arizona Cardinals
17 :  20
Tampa Bay Buccaneers

Nov 9, 2025 - NFL

Arizona Cardinals
22 :  44
Seattle Seahawks

Nov 3, 2025 - NFL

Arizona Cardinals
27 :  17
Dallas Cowboys

Oct 12, 2025 - NFL

Arizona Cardinals
27 :  31
Indianapolis Colts

Sep 21, 2025 - NFL

Arizona Cardinals
15 :  16
San Francisco 49ers

Sep 7, 2025 - NFL

Arizona Cardinals
20 :  13
New Orleans Saints
Houston Texans
Houston Texans Latest matches
L W W W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Dec 7, 2025 - NFL

Houston Texans
20 :  10
Kansas City Chiefs

Nov 30, 2025 - NFL

Houston Texans
20 :  16
Indianapolis Colts

Nov 20, 2025 - NFL

Buffalo Bills
19 :  23
Houston Texans

Nov 16, 2025 - NFL

Houston Texans
16 :  13
Tennessee Titans

Nov 9, 2025 - NFL

Jacksonville Jaguars
29 :  36
Houston Texans

Nov 2, 2025 - NFL

Denver Broncos
18 :  15
Houston Texans
L W W L W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 20, 2025 - NFL

Buffalo Bills
19 :  23
Houston Texans

Nov 9, 2025 - NFL

Jacksonville Jaguars
29 :  36
Houston Texans

Nov 2, 2025 - NFL

Denver Broncos
18 :  15
Houston Texans

Oct 26, 2025 - NFL

San Francisco 49ers
15 :  26
Houston Texans

Sep 28, 2025 - NFL

Tennessee Titans
0 :  26
Houston Texans

Sep 15, 2025 - NFL

Tampa Bay Buccaneers
20 :  19
Houston Texans
L W L W W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Dec 7, 2025 - NFL

Houston Texans
20 :  10
Kansas City Chiefs

Nov 30, 2025 - NFL

Houston Texans
20 :  16
Indianapolis Colts

Nov 16, 2025 - NFL

Houston Texans
16 :  13
Tennessee Titans

Oct 20, 2025 - NFL

Houston Texans
19 :  27
Seattle Seahawks

Oct 5, 2025 - NFL

Houston Texans
44 :  10
Baltimore Ravens

Sep 21, 2025 - NFL

Houston Texans
10 :  17
Jacksonville Jaguars

Arizona Cardinals against Houston Texans : Head to Head (H2H)

Nov 19, 2023 - NFL

Arizona Cardinals
16 :  21
Houston Texans

Arizona Cardinals - Houston Texans Key Points

  1. The Texans are on a 5 game winning run
  2. The Cardinals are on a 5 game losing run
  3. Houston's last 5 wins have all been by 10 points or less
  4. 7 of Arizona's 10 losses this seaosn have been 1 score games

Our Arizona Cardinals vs Houston Texans Prediction

Houston are on fire at the moment, and given the open nature of the AFC playoff field, they will fancy their chances of making a deep postseason run. 

The Cardinals' 3-10 record does not tell the full story of their season. Arizona have been competitive in the majority of their losses, and their overall performances have been a lot better than their record suggests. 

So whilst we think the Texans will have too much for Arizona on Sunday, we would not be surprised to see the Cards keep this tight. 

Our prediction for Houston Texans vs Arizona Cardinals is: Cardinals (+9.5) to win. 

Prediction:

 

Cardinals (+9.5) to win

-111
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Arizona Cardinals vs Houston Texans Picks