Los Angeles Rams vs Detroit Lions Prediction & Picks - NFL

Prediction published on 12/14/25, 1:06 PM  by Lou Aguila | Modified on 12/15/25 at 1:14 AM in NFL Picks

Matthew Stafford and the Los Angeles Rams will host Jared Goff and the Detroit Lions in a crucial match-up on Sunday at SoFi Stadium.

The Rams are -270 favorites against the Lions, who are 11-3 in their last 14 games on the road.

Current Form:

The 10-3 Rams are in a two-way tie with the Seahawks for the No.1 spot in the NFC West. Los Angeles has won 7 of its last 8 games, including a 45-17 rout of the Arizona Cardinals. For the third consecutive time and fifth in the last six games, Stafford threw over 200 passing yards as he passed for 281 yards with three touchdowns to spearhead the Rams’ offense. LA also flexed its lockdown defense, hounding the Cardinals to 314 total yards and 17 points.

The Lions are 8-5 in the NFC North, two games behind the division-leading Green Bay Packers (9-3) and a game below the Chicago Bears (9-4). Detroit shot down the Dallas Cowboys, 44-33, last week behind a suffocating defense and dynamic performance from the rushing crew. Jahmyr Gibbs ran for 43 yards on 12 carries with three scores, while David Montgomery covered 60 passing yards with one TD.