CF America vs Club Santos Laguna Prediction & Picks - Liga MX

Mexico - Liga MX

CF America
10/4/25 23:05
Club Santos Laguna

Prediction:

 

América -2.5.

+135
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 by Carlos Zabala in Liga MX Picks

For Matchday 12 of the Liga MX, no team will be as much of a betting favorite as América when they face Santos Laguna. The last time this matchup took place in the Mexican capital was in October 2024, when América won 3-0, albeit with all the goals scored after the 78th minute; that was a match in which Ismael Govea was sent off.

Santos Laguna, in a way, has finally shaken off the worst sporting and institutional crisis the team endured throughout the previous Clausura tournament, in which they finished last in the table, losing each of their last six matches to close out that tournament. Victories have not been a constant for the Torreón team in the new Apertura tournament, but they did at least score 1-0 wins against Chivas and Tijuana at Estadio Corona. However, on the road, Santos only collected one of a possible 15 points in this Apertura tournament. They are coming off a 1-0 loss to Monterrey at the Bancomer Stadium, although it was a narrower result than the sportsbooks had expected.

América doesn't want to concede any more ground to Toluca as the dominant force in Mexican soccer and made a significant impact by outperforming Pumas in every aspect in the previous match, which América won 4-1.

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CF America vs Club Santos Laguna Form

Table

Teams Pts P W D L GD
3
CF America
CF America
24 11 7 3 1 12
13
Club Santos Laguna
Club Santos Laguna
10 11 3 1 7 -5

CF America and Club Santos Laguna Latest Matches

CF America
CF America Latest matches
W W L D W W
Victories

4/6 (67%)

Draw

1/6 (17%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

3.5 Total goals
67% BTTS
2.33 Goals scored
1.17 Goals conceded
67% Over 2.5
33% Under 2.5

Sep 27, 2025 - Liga MX

CF America
4 :  1
Pumas UNAM

Sep 24, 2025 - Liga MX

Atletico San Luis
0 :  1
CF America

Sep 20, 2025 - Liga MX

Monterrey
2 :  2
CF America

Sep 13, 2025 - Liga MX

CF America
1 :  2
Chivas

Aug 30, 2025 - Liga MX

CF America
2 :  0
CF Pachuca

Aug 24, 2025 - Liga MX

Atlas FC
2 :  4
CF America
D D W W L W
Victories

3/6 (50%)

Draw

2/6 (33%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

3.17 Total goals
67% BTTS
2 Goals scored
1.17 Goals conceded
50% Over 2.5
50% Under 2.5

Sep 27, 2025 - Liga MX

CF America
4 :  1
Pumas UNAM

Sep 13, 2025 - Liga MX

CF America
1 :  2
Chivas

Aug 30, 2025 - Liga MX

CF America
2 :  0
CF Pachuca

Aug 9, 2025 - Liga MX

CF America
1 :  0
Queretaro

Aug 6, 2025 - Leagues Cup

CF America
1 :  1
Portland Timbers

Aug 2, 2025 - Leagues Cup

CF America
3 :  3
Minnesota United
D D W W D W
Victories

3/6 (50%)

Draw

3/6 (50%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

3.17 Total goals
83% BTTS
2 Goals scored
1.17 Goals conceded
50% Over 2.5
50% Under 2.5

Sep 24, 2025 - Liga MX

Atletico San Luis
0 :  1
CF America

Sep 20, 2025 - Liga MX

Monterrey
2 :  2
CF America

Aug 24, 2025 - Liga MX

Atlas FC
2 :  4
CF America

Aug 16, 2025 - Liga MX

Tigres UANL
1 :  3
CF America

Jul 26, 2025 - Liga MX

Club Necaxa
1 :  1
CF America

Jul 11, 2025 - Liga MX

FC Juarez
1 :  1
CF America
Club Santos Laguna
Club Santos Laguna Latest matches
L L D L W L
Victories

1/6 (17%)

Draw

1/6 (17%)

Defeats

4/6 (67%)

Average stats (Last 6 matchs)

2.5 Total goals
50% BTTS
0.83 Goals scored
1.67 Goals conceded
50% Over 2.5
50% Under 2.5

Sep 27, 2025 - Liga MX

Monterrey
1 :  0
Club Santos Laguna

Sep 24, 2025 - Liga MX

Club Santos Laguna
1 :  0
Tijuana

Sep 21, 2025 - Liga MX

Club Santos Laguna
1 :  4
Atletico San Luis

Sep 13, 2025 - Liga MX

Atlas FC
2 :  2
Club Santos Laguna

Aug 30, 2025 - Liga MX

Club Santos Laguna
0 :  1
Tigres UANL

Aug 22, 2025 - Liga MX

FC Juarez
2 :  1
Club Santos Laguna
W L W L L W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

2.83 Total goals
33% BTTS
1.33 Goals scored
1.5 Goals conceded
50% Over 2.5
50% Under 2.5

Sep 24, 2025 - Liga MX

Club Santos Laguna
1 :  0
Tijuana

Sep 21, 2025 - Liga MX

Club Santos Laguna
1 :  4
Atletico San Luis

Aug 30, 2025 - Liga MX

Club Santos Laguna
0 :  1
Tigres UANL

Aug 10, 2025 - Liga MX

Club Santos Laguna
1 :  0
Chivas

Jul 16, 2025 - Liga MX

Club Santos Laguna
2 :  4
Deportivo Toluca FC

Jul 12, 2025 - Liga MX

Club Santos Laguna
3 :  0
Pumas UNAM
L L L L D L
Victories

0/6 (0%)

Draw

1/6 (17%)

Defeats

5/6 (83%)

Average stats (Last 6 matchs)

3.33 Total goals
67% BTTS
1 Goals scored
2.33 Goals conceded
83% Over 2.5
17% Under 2.5

Sep 27, 2025 - Liga MX

Monterrey
1 :  0
Club Santos Laguna

Sep 13, 2025 - Liga MX

Atlas FC
2 :  2
Club Santos Laguna

Aug 22, 2025 - Liga MX

FC Juarez
2 :  1
Club Santos Laguna

Aug 16, 2025 - Liga MX

CF Cruz Azul
3 :  2
Club Santos Laguna

Aug 7, 2025 - Leagues Cup

Los Angeles Galaxy
4 :  0
Club Santos Laguna

Aug 3, 2025 - Leagues Cup

Seattle Sounders
2 :  1
Club Santos Laguna

CF America against Club Santos Laguna : Head to Head (H2H)

CF America

60 %

Draw

40 %

Club Santos Laguna

0 %

Average stats (last H2H results)

4.2
Total goals
80%
BTTS
2.8
Goals scored (Team 1)
1.4
Goals scored (Team 2)
80%
Over 2.5
20%
Under 2.5

Jan 25, 2025 - Liga MX

Club Santos Laguna
1 :  4
CF America

Oct 19, 2024 - Liga MX

CF America
3 :  0
Club Santos Laguna

Apr 6, 2024 - Liga MX

Club Santos Laguna
1 :  1
CF America

Oct 21, 2023 - Liga MX

CF America
4 :  3
Club Santos Laguna

Feb 4, 2023 - Liga MX

Club Santos Laguna
2 :  2
CF America

Club Santos Laguna v CF America last Lineups

CF America

Formation : 4 - 2 - 3 - 1

1
L. Malagon
3
I. Reyes
26
C. Borja
29
R. Juarez
4
S. Caceres
5
K. Alvarez
8
A. Fidalgo
20
A. Gutierrez
10
A. Zendejas
19
J. Zuniga
97
A. Saint-Maximin
8
S. Mariscal
26
R. Sordo
13
J. Ocejo
7
C. Dajome
35
K. Balanta
6
J. Guemez
4
J. Abella
5
A. Lopez
188
J. Perez
2
B. Amione
1
C. Acevedo

Formation : 4 - 4 - 2

Club Santos Laguna

Missing players

CF America
CF America
Midfielder

J. Dos Santos

D. Espinoza

Club Santos Laguna
Club Santos Laguna
Forward

F. Fagundez

Most goals and assists

CD Huachipato CF America
CD Huachipato Club Santos Laguna
Top Goalscorer
USA A. Zendejas (14 Goals)
Top Goalscorer
Chile B. Barticciotto (8 Goals)
Best assists
USA A. Zendejas (9 Assists)
Best assists
Spain F. Villalba (4 Assists)

CF America and Club Santos Laguna Stats in Liga MX

CF America
CF America
Club Santos Laguna
Club Santos Laguna
64%
Victories
27%
27%
Draw
9%
9%
Defeats
64%
3.09
Total goals per match
2.82
2.09
Goals scored per match
1.18
1
Goals conceded per match
1.64
55%
Over 2.5
55%
45%
Under 2.5
45%
73%
BTTS
45%
27%
No goals conceded
27%

CF America - Club Santos Laguna Key Points

  1. América generated an xG of 3.48 in the match against Pumas
  2. Monterrey completed 91% of their attempted passes in the win against Santos Laguna
  3. Santos Laguna hasn't beaten América since 2018
  4. Zendejas leads América in goals this Liga MX season with five, in addition to two assists
Up to $200 to bet on CF America - Club Santos Laguna! 

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Our CF America vs Club Santos Laguna Prediction

A highly unlikely Santos Laguna victory would pay odds at betting sites as high as +1050, but given the Torreón team's repeated defensive issues, a rout seems more likely than Santos' first win over América in seven years.

Santos has become a highly undisciplined team, committing simple fouls, so much so that in four of their last seven matches, they've received a red card; Choco Lozano's in the last, meaning the Honduran will not play against América.

Zendejas has been América's welcome revelation this year; his market value has risen to almost €10 million, following outstanding performances like the last two against Atlético San Luis and Pumas, where he scored goals and was the best player on the pitch.

Our prediction for Santos Laguna vs Club América is: América -2.5.

Prediction:

 

América -2.5.

+135
$200 offered for betting!

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CF America vs Club Santos Laguna Picks
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