Oregon Ducks vs UCLA Bruins Prediction & Picks - NCAA

USA - NCAA

Oregon Ducks
10/10/26 15:30
UCLA Bruins

Prediction:

 

UCLA Bruins +11.5

-110
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 by Matt Lowrimore | in NCAA Picks

Another huge game on the Week 6 College Football Saturday slate will feature a Big Ten matchup between the #21-ranked UCLA Bruins and the #13-ranked Oregon Ducks. Let’s take a look at the match statistics and predictions for this game between the Bruins and the Ducks.

UCLA enters this game with a record of 4-0 and 2-0 in the Big Ten. The Bruins are coming off their bye week and most recently beat Maryland in Week 4 by a score of 54-3. In this game, UCLA produced 475 yards of offense, while allowing 181 yards. Despite not having been tested, the Bruins’ offense has been more than efficient this season, which suggests they could have success against an Oregon defense that has been vulnerable at times this season.

As for Oregon, they enter this game with a record of 3-1 and 1-0 in the Big Ten. The Ducks are also coming off their bye week and most recently beat USC in Week 4 by a score of 41-27. Oregon had 504 yards of offense in this game, but allowed 446 yards. One issue that remains for the Ducks is the status of their quarterback, Dante Moore. He is a game-time decision for this matchup, so if he cannot play, Oregon could be in trouble.

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Oregon Ducks vs UCLA Bruins Form

Table

Oregon Ducks and UCLA Bruins Latest Matches

Oregon Ducks
Oregon Ducks Latest matches
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 26, 2026 - NCAA

USC Trojans
27 :  41
Oregon Ducks

Sep 18, 2026 - NCAA

Oregon Ducks
84 :  0
Portland State Vikings

Sep 12, 2026 - NCAA

Oklahoma State Cowboys
39 :  31
Oregon Ducks

Sep 5, 2026 - NCAA

Oregon Ducks
34 :  27
Boise State Broncos

Jan 9, 2026 - NCAA

Indiana Hoosiers
56 :  22
Oregon Ducks

Jan 1, 2026 - NCAA

Texas Tech Red Raiders
0 :  23
Oregon Ducks
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Sep 18, 2026 - NCAA

Oregon Ducks
84 :  0
Portland State Vikings

Sep 5, 2026 - NCAA

Oregon Ducks
34 :  27
Boise State Broncos

Dec 20, 2025 - NCAA

Oregon Ducks
51 :  34
James Madison Dukes

Nov 22, 2025 - NCAA

Oregon Ducks
42 :  27
USC Trojans

Nov 14, 2025 - NCAA

Oregon Ducks
42 :  13
Minnesota Golden Gophers

Oct 25, 2025 - NCAA

Oregon Ducks
21 :  7
Wisconsin Badgers
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 26, 2026 - NCAA

USC Trojans
27 :  41
Oregon Ducks

Sep 12, 2026 - NCAA

Oklahoma State Cowboys
39 :  31
Oregon Ducks

Jan 9, 2026 - NCAA

Indiana Hoosiers
56 :  22
Oregon Ducks

Jan 1, 2026 - NCAA

Texas Tech Red Raiders
0 :  23
Oregon Ducks

Nov 29, 2025 - NCAA

Washington Huskies
14 :  26
Oregon Ducks

Nov 8, 2025 - NCAA

Iowa Hawkeyes
16 :  18
Oregon Ducks
UCLA Bruins
UCLA Bruins Latest matches
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 26, 2026 - NCAA

Maryland Terrapins
3 :  54
UCLA Bruins

Sep 19, 2026 - NCAA

UCLA Bruins
52 :  38
Purdue Boilermakers

Sep 12, 2026 - NCAA

UCLA Bruins
28 :  10
San Diego State Aztecs

Sep 5, 2026 - NCAA

California Golden Bears
24 :  45
UCLA Bruins

Nov 29, 2025 - NCAA

USC Trojans
29 :  10
UCLA Bruins

Nov 22, 2025 - NCAA

UCLA Bruins
14 :  48
Washington Huskies
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 19, 2026 - NCAA

UCLA Bruins
52 :  38
Purdue Boilermakers

Sep 12, 2026 - NCAA

UCLA Bruins
28 :  10
San Diego State Aztecs

Nov 22, 2025 - NCAA

UCLA Bruins
14 :  48
Washington Huskies

Nov 8, 2025 - NCAA

UCLA Bruins
21 :  28
Nebraska Cornhuskers

Oct 18, 2025 - NCAA

UCLA Bruins
20 :  17
Maryland Terrapins

Sep 12, 2025 - NCAA

UCLA Bruins
10 :  35
New Mexico Lobos
W L L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 26, 2026 - NCAA

Maryland Terrapins
3 :  54
UCLA Bruins

Sep 5, 2026 - NCAA

California Golden Bears
24 :  45
UCLA Bruins

Nov 29, 2025 - NCAA

USC Trojans
29 :  10
UCLA Bruins

Nov 15, 2025 - NCAA

Ohio State Buckeyes
48 :  10
UCLA Bruins

Oct 25, 2025 - NCAA

Indiana Hoosiers
56 :  6
UCLA Bruins

Oct 11, 2025 - NCAA

Michigan State Spartans
13 :  38
UCLA Bruins

Oregon Ducks against UCLA Bruins : Head to Head (H2H)

Oregon Ducks

100 %

UCLA Bruins

0 %

Sep 28, 2024 - NCAA

UCLA Bruins
13 :  34
Oregon Ducks
Oregon Ducks vs UCLA Bruins Picks

Oregon Ducks - UCLA Bruins Key Points

  1. UCLA is 4-0 ATS this season
  2. UCLA is averaging 44.8 points per game this season
  3. Oregon is 2-2 ATS this season
  4. Oregon is averaging 47.5 points per game this season
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Our Oregon Ducks vs UCLA Bruins Prediction

Oregon is the heavy favorite in this game; however, UCLA looks to be the best betting option. Most notably, UCLA is 4-0 against the spread this season. While most of these games saw them as the favorite, it still tells us they have been able to take care of their business without issue. 

Of course, playing at Oregon will be a completely different test, but with Oregon just 2-2 against the spread this season and with the status of their quarterback still a huge question mark, it suggests this game will be much more competitive than expected. Because of this, our UCLA Bruins vs. Oregon Ducks prediction is: UCLA Bruins +11.5.

Prediction:

 

UCLA Bruins +11.5

-110
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.