Los Angeles Lakers vs San Antonio Spurs Prediction & Picks - NBA
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by Paul Tamayo | in NBA Picks
The San Antonio Spurs (16-7) visit the Los Angeles Lakers (17-6) in an NBA Cup quarterfinals game on Wednesday, December 10, at the Crypto.com Arena.
The Lakers look to keep their strong start going when they host the Spurs on Wednesday. They are coming off an impressive 112-108 win over the Philadelphia 76ers, where they erased a seven-point halftime deficit behind LeBron James’ late go-ahead three.
Along with LeBron's heroics, Luka Doncic also came through with a triple-double performance of 31 points, 15 rebounds, and 11 assists.
It has been a lukewarm stretch for the Lakers, as they lost two of their last five games. This recent road win against the Sixers should be a morale booster for the team.
As for the Spurs, they’ve won four of their last five games and are fresh off a wild 135-132 victory over the New Orleans Pelicans. San Antonio built a 20-point halftime lead, then nearly collapsed in the third quarter before rookie Dylan Harper’s go-ahead floater with nine seconds left sealed the win.
Harper finished with 22 markers, reinforcing veteran forward Harrison Barnes, who had a team-high 24.
The Spurs will continue to miss Victor Wembanyama on Wednesday, while the Lakers have Maxi Kleber listed as day-to-day.
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Los Angeles Lakers vs San Antonio Spurs Form
Table
| Teams | % | P | W | L | Series |
|---|---|---|---|---|---|
|
2
|
0.756 | 82 | 62 | 20 | |
|
6
|
0.646 | 82 | 53 | 29 | 3 |
Los Angeles Lakers and San Antonio Spurs Latest Matches
4/6 (67%)
2/6 (33%)
Dec 7, 2025 - NBA
Dec 5, 2025 - NBA
Dec 4, 2025 - NBA
Dec 1, 2025 - NBA
Nov 30, 2025 - NBA
Nov 28, 2025 - NBA
5/6 (83%)
1/6 (17%)
Dec 1, 2025 - NBA
Nov 30, 2025 - NBA
Nov 28, 2025 - NBA
Nov 25, 2025 - NBA
Nov 18, 2025 - NBA
Nov 5, 2025 - NBA
5/6 (83%)
1/6 (17%)
Dec 7, 2025 - NBA
Dec 5, 2025 - NBA
Dec 4, 2025 - NBA
Nov 23, 2025 - NBA
Nov 15, 2025 - NBA
Nov 14, 2025 - NBA
4/6 (67%)
2/6 (33%)
Dec 8, 2025 - NBA
Dec 5, 2025 - NBA
Dec 3, 2025 - NBA
Dec 2, 2025 - NBA
Nov 30, 2025 - NBA
Nov 28, 2025 - NBA
4/6 (67%)
2/6 (33%)
Dec 2, 2025 - NBA
Nov 20, 2025 - NBA
Nov 18, 2025 - NBA
Nov 16, 2025 - NBA
Nov 14, 2025 - NBA
Nov 12, 2025 - NBA
4/6 (67%)
2/6 (33%)
Dec 8, 2025 - NBA
Dec 5, 2025 - NBA
Dec 3, 2025 - NBA
Nov 30, 2025 - NBA
Nov 28, 2025 - NBA
Nov 26, 2025 - NBA
Los Angeles Lakers against San Antonio Spurs : Head to Head (H2H)
83 %
17 %
Nov 5, 2025 - NBA
Jul 8, 2025 - NBA Summer League
Mar 17, 2025 - NBA
Jan 13, 2025 - NBA
Nov 27, 2024 - NBA
Nov 15, 2024 - NBA
Players list
A. Reaves
L. James
R. Hachimura
S. Castle
D. Fox
H. Barnes
Substitutes
G. Vincent
D. Knecht
B. James
M. Smart
J. Laravia
A. Thiero
J. Vanderbilt
J. Champagnie
D. Harper
J. McLaughlin
L. Waters III
J. Sochan
C. Bryant
Los Angeles Lakers - San Antonio Spurs Key Points
- The Lakers are coming off a 112-108 win against the Philadelphia 76ers.
- The Spurs are coming off a 135-132 win over the New Orleans Pelicans.
- The Lakers have a better offensive rating than the Spurs.
- The Spurs have won four of their last five games.
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Our Los Angeles Lakers vs San Antonio Spurs Prediction
After their clutch victory in Philadelphia, the Lakers return home with much-needed momentum. LeBron James played in his best form since his return, and they all have their stars healthy for this NBA Cup quarterfinals match on Wednesday.
Meanwhile, the Spurs have been impressive recently, but they're still missing the services of their dynamic big man Victor Wembanyama. The healthy Lakers have the advantage in this game. Our prediction for the Los Angeles Lakers vs San Antonio Spurs match is: Lakers (-5.5) cover the spread.All tips are fully researched and given in good faith, but profits cannot be guaranteed.
