Chicago Fire vs Orlando City SC Prediction & Picks - Major League Soccer

USA - Major League Soccer

Chicago Fire
10/22/25 20:30
Orlando City SC

Prediction:

 

Over 3.0 Asian Total

+105
$300 offered for betting!

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 by Bradley Gibbs in Major League Soccer Picks

The 2025 Major League Soccer playoffs are upon us. After a long regular season, it's now all about paving a way to MLS Cup Final. Before we get the best-of-three series underway, we have the shootout games. Kicking things off on Wednesday evening will be Chicago Fire and Orlando City, who'll clash at Soldier Field, where the Fire will be hoping that home advantage helps them to get over the line and into the next stage of the postseason. 

When the regular season was all said and done, there was very little between these two teams, with the Chicagoo Fire finishing eighth in the Eastern Conference, slotting in ahead of Wednesday's visitors on goal difference alone. Will the two teams be as closely matched when they take to the field in Illinois? Time will soon tell. 

Chicago Fire vs Orlando City SC Form

Chicago Fire and Orlando City SC Latest Matches

Chicago Fire
Chicago Fire Latest matches
L W W W D D
Victories

3/6 (50%)

Draw

2/6 (33%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

4.17 Total goals
67% BTTS
2.5 Goals scored
1.67 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 18, 2025 - Major League Soccer

New England Revolution
2 :  2
Chicago Fire

Oct 4, 2025 - Major League Soccer

Chicago Fire
2 :  2
Toronto FC

Sep 30, 2025 - Major League Soccer

Inter Miami
3 :  5
Chicago Fire

Sep 27, 2025 - Major League Soccer

Chicago Fire
2 :  0
Columbus Crew

Sep 20, 2025 - Major League Soccer

Minnesota United
0 :  3
Chicago Fire

Sep 13, 2025 - Major League Soccer

Chicago Fire
1 :  3
New York City
D W W L W D
Victories

3/6 (50%)

Draw

2/6 (33%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

4 Total goals
83% BTTS
2.17 Goals scored
1.83 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 4, 2025 - Major League Soccer

Chicago Fire
2 :  2
Toronto FC

Sep 27, 2025 - Major League Soccer

Chicago Fire
2 :  0
Columbus Crew

Sep 13, 2025 - Major League Soccer

Chicago Fire
1 :  3
New York City

Sep 6, 2025 - Major League Soccer

Chicago Fire
3 :  2
New England Revolution

Aug 16, 2025 - Major League Soccer

Chicago Fire
3 :  2
Saint Louis City SC

Aug 9, 2025 - Major League Soccer

Chicago Fire
2 :  2
Los Angeles FC
D W L W W D
Victories

3/6 (50%)

Draw

2/6 (33%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

4.17 Total goals
50% BTTS
2.33 Goals scored
1.83 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 18, 2025 - Major League Soccer

New England Revolution
2 :  2
Chicago Fire

Sep 30, 2025 - Major League Soccer

Inter Miami
3 :  5
Chicago Fire

Sep 20, 2025 - Major League Soccer

Minnesota United
0 :  3
Chicago Fire

Aug 23, 2025 - Major League Soccer

Philadelphia Union
4 :  0
Chicago Fire

Jul 19, 2025 - Major League Soccer

CF Montreal
0 :  2
Chicago Fire

Jul 16, 2025 - Major League Soccer

Atlanta United Fc
2 :  2
Chicago Fire
Orlando City SC
Orlando City SC Latest matches
D W D D L L
Victories

1/6 (17%)

Draw

3/6 (50%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

3.33 Total goals
100% BTTS
1.5 Goals scored
1.83 Goals conceded
50% Over 2.5
50% Under 2.5

Oct 18, 2025 - Major League Soccer

Toronto FC
4 :  2
Orlando City SC

Oct 11, 2025 - Major League Soccer

Orlando City SC
1 :  2
Vancouver Whitecaps

Oct 4, 2025 - Major League Soccer

Orlando City SC
1 :  1
Columbus Crew

Sep 28, 2025 - Major League Soccer

FC Cincinnati
1 :  1
Orlando City SC

Sep 20, 2025 - Major League Soccer

Orlando City SC
3 :  2
Nashville SC

Sep 13, 2025 - Major League Soccer

DC United
1 :  1
Orlando City SC
W W W W D L
Victories

4/6 (67%)

Draw

1/6 (17%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

4.17 Total goals
100% BTTS
2.83 Goals scored
1.33 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 11, 2025 - Major League Soccer

Orlando City SC
1 :  2
Vancouver Whitecaps

Oct 4, 2025 - Major League Soccer

Orlando City SC
1 :  1
Columbus Crew

Sep 20, 2025 - Major League Soccer

Orlando City SC
3 :  2
Nashville SC

Aug 16, 2025 - Major League Soccer

Orlando City SC
3 :  1
Sporting Kansas City

Aug 10, 2025 - Major League Soccer

Orlando City SC
4 :  1
Inter Miami

Aug 6, 2025 - Leagues Cup

Orlando City SC
5 :  1
Club Necaxa
L L L D D L
Victories

0/6 (0%)

Draw

2/6 (33%)

Defeats

4/6 (67%)

Average stats (Last 6 matchs)

3.83 Total goals
100% BTTS
1.17 Goals scored
2.67 Goals conceded
67% Over 2.5
33% Under 2.5

Oct 18, 2025 - Major League Soccer

Toronto FC
4 :  2
Orlando City SC

Sep 28, 2025 - Major League Soccer

FC Cincinnati
1 :  1
Orlando City SC

Sep 13, 2025 - Major League Soccer

DC United
1 :  1
Orlando City SC

Aug 31, 2025 - Leagues Cup

Los Angeles Galaxy
2 :  1
Orlando City SC

Aug 27, 2025 - Leagues Cup

Inter Miami
3 :  1
Orlando City SC

Aug 23, 2025 - Major League Soccer

Nashville SC
5 :  1
Orlando City SC

Chicago Fire against Orlando City SC : Head to Head (H2H)

Chicago Fire

17 %

Draw

33 %

Orlando City SC

50 %

Average stats (last H2H results)

3.33
Total goals
83%
BTTS
1.33
Goals scored (Team 1)
2
Goals scored (Team 2)
67%
Over 2.5
33%
Under 2.5

May 31, 2025 - Major League Soccer

Orlando City SC
1 :  3
Chicago Fire

May 3, 2025 - Major League Soccer

Chicago Fire
0 :  0
Orlando City SC

Jun 22, 2024 - Major League Soccer

Orlando City SC
4 :  2
Chicago Fire

May 29, 2024 - Major League Soccer

Chicago Fire
1 :  1
Orlando City SC

Aug 20, 2023 - Major League Soccer

Chicago Fire
1 :  3
Orlando City SC

Jul 1, 2023 - Major League Soccer

Orlando City SC
3 :  1
Chicago Fire
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Chicago Fire - Orlando City SC: Form Analysis

It was definitely the hosts who finished the campaign in better style, with the Fire avoiding defeat in each of their final five regular season games. They managed to emerge successful from three of those five, though they now head into this huge game off the back of consecutive ties, tying 2-2 with Toronto FC at home, before finishing the regular season with a 2-2 tie in New England. Such form doesn't exactly suggest that they'll make light work of this tricky assignment. 

Then again, it's not as if the late-season form of the visitors certainly doesn't point towards away-day dominance in Chicago. The Lions fell over the lines as far as finishing in the top nine is concerned, losing each of their last two regular-season games, failing to win any of their last four. They'll definitely need to step on the gas to get it done at Soldier Field.

Chicago Fire against Orlando City SC Lineups: Starting 11

Chicago Fire

Formation : 4 - 3 - 3

1
C. Brady
24
J. Dean
3
J. Elliott
16
J. Waterman
15
A. Gutman
35
S. Oregel
42
D. D'avilla
17
B. Gutierrez
11
P. Zinckernagel
9
H. Cuypers
19
J. Bamba
10
M. Ojeda
13
D. McGuire
77
I. Angulo
5
C. Araujo
20
E. Atuesta
87
M. Pasalic
4
D. Brekalo
6
R. Jansson
15
R. Schlegel
30
A. Freeman
1
P. Gallese

Formation : 4 - 4 - 2

Orlando City SC

Missing players

Chicago Fire
Chicago Fire
Defender

L. Barroso

V. Radojevic

Midfielder

A. Franco

Forward

C. Mueller

Orlando City SC
Orlando City SC
Defender

T. Reid-Brown

Midfielder

J. Gerbet

W. Cartagena

S. Mohammed

Forward

G. Caraballo

Y. Tsukada

Chicago Fire & Orlando City SC Squad Analysis

The hosts will continue to be without the services of Leonardo Barroso, who sustained an injury against the Columbus Crew recently, while Andre France is also out having picked up a knock against Inter Miami. Chris Mueller continues as a long-term absentee, as does Viktor Radojevic. Thankfully, there are no serious injury concerns for head coach for Gregg Berhalter to contend with, leaving the former Stars and Stripes boss to field what is pretty much his best XI. 

The visitors have only one genuinely serious injury right now, with midfielder destroyer Wilder Cartagena out with a achilles tendon problem. Youngster Gustavo Carabello is also out, while Joran Gerbet is another absentee. Oscar Pareja can still pick a strong side, though, so if the visitors lose this, it won't be because of injury issues. 

Most goals and assists

CD Huachipato Chicago Fire
CD Huachipato Orlando City SC
Top Goalscorer
Belgium H. Cuypers (19 Goals)
Top Goalscorer
Argentina M. Ojeda (16 Goals)
Best assists
Denmark P. Zinckernagel (15 Assists)
Best assists
Argentina M. Ojeda (11 Assists)

Chicago Fire - Orlando City SC Key Points

  1. When the pair last met, back in June, four goals were scored.
  2. Each of Chicago's last three games has contained at least four goals.
  3. Four or more goals have been scored in five of Chicago's last six MLS games at Soldier Field.
  4. The visitors have regularly been involved in high-scoring games away from home this season.

Our Chicago Fire vs Orlando City SC Prediction

As far as I'm concerned, the overriding factor here is that neither team can defend sufficiently, and I'm just not sure that the early market is quite factoring in the importance of this enough. Both teams have struggled massively at the back in recent weeks, which means that neither can really afford to rely on any sort of defensive ability to get over the line here.

It's do or die for both, so don't be surprised to see both teams go for it, which could quite easily lead to a high-scoring game, which is exactly what happened when the pair shared four goals back in June. Our Chicago Fire vs Orlando City Pick: Over 3.0 Asian Total. 

Prediction:

 

Over 3.0 Asian Total

+105
$300 offered for betting!

Chicago Fire vs Orlando City SC - Other Interesting Picks

Philip Zinckernagel to Receive a Card

Odds +380
As an secondary betting option, consider taking Fire midfielder Philip Zinckernagel to pick up a card. The Dane has been no stranger to stepping beyond the rules this season, fouling with serious regularity. He was booked in Chicago's most recent home game, while he comes into this huge game having made eight fouls in his last two appearances. Throw in that Zinckernagel averages 1.96 fouls per 90 minutes this season and odds of +380 look very appealing indeed.
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Chicago Fire vs Orlando City SC Picks